Efficacy of aerobic exercise for HIV-associated neurocognitive disorders receiving ART: An RCT by Martins Nweke, Nombeko Mshunqane

Subjects: “…aerobic exercise, randomised controlled trial…”
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Effect of environmental enrichment on relapse rates in patients with severe alcohol use disorder: protocol for a randomised controlled trial by Lila Barillot, Claudia Chauvet, Marc Besnier, Nematollah Jaafari, Marcello Solinas, Armand Chatard

“…Our EE will allow an enhancement of the standard intervention, and will combine several promising enrichment factors identified in the literature—physical activity, cognitive stimulation, mindfulness and virtual reality (VR).Methods and analysis A randomised controlled trial involving 135 participants receiving treatment for severe AUD will be conducted. …”
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Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine by Philip M Bath, Alan A Montgomery, Lisa J Woodhouse, Polly Scutt

“…The leading researchers for eligible trials were approached and asked to share IPD including trial characteristics, patient demographics, baseline clinical data and outcome measures.Participants Participants in eligible randomised controlled trials included patients with or at risk of cognitive decline/vascular events.Primary and secondary outcome measures Numbers (%) of trials where the leading researcher responded favourably/negatively or did not respond. …”
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Efficacy of Topical Corticosteroid vs PUVAsol Following Split Thickness Grafting in Stable Vitiligo: A Randomised Control Trial by Prafull Mehta, Chinmai Yadav, Ramesh Kumar, Suresh Jain

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A Randomised Controlled Trial Comparing Chemomechanical (Carie-Care™) Versus Conventional Caries Removal for Atraumatic Restorative Treatment by Saloni Gupta, Kalyana Chakravarthy Pentapati, Shashidhar Acharya

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Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

“…Introduction Steroids In caRdiac Surgery trial (SIRS) is a large international randomised controlled trial of methylprednisolone or placebo in patients undergoing cardiac surgery with the use of a cardiopulmonary bypass pump. …”
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Digital cognitive training in children with attention-deficit/hyperactivity disorder: a study protocol of a randomised controlled trial by Sally Richmond, Hannah Kirk, Kim Cornish, Mark A Bellgrove, Tori Gaunson, Meg Bennett

“…This study aims to assess the immediate and long-term efficacy of an attention training intervention in children with ADHD.Methods and analysis This study is a preregistered, parallel, double blind, randomised controlled trial. Participants will comprise 104 children with a diagnosis of ADHD aged 5–8 years 11 months. …”
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Cost-effectiveness of metacognitive therapy for cardiac rehabilitation participants with symptoms of anxiety and/or depression: analysis of a randomised controlled trial by David Reeves, Calvin Heal, Patrick Joseph Doherty, Gemma E Shields, Adrian Wells, Lora Capobianco, Anthony Heagerty, Deborah Buck, Linda M Davies, Elizabeth Camacho

“…The objective of this within-trial economic evaluation was to compare the cost-effectiveness of metacognitive therapy (MCT) plus usual care (UC) to UC, from a health and social care perspective in the UK.Methods A multicentre, single-blind, randomised controlled trial (ISRCTN74643496) was conducted in the UK involving 332 patients with CR with elevated symptoms of anxiety and/or depression and compared group-based MCT with UC. …”
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Nurse-led counselling programme on the adherence to eye patch application among children with amblyopia: a randomised control trial by Srishti Raj, Savleen Kaur, Mona Duggal, Shivani ­, Sushma Kumari Saini

“…Objective To assess the impact of the nurse-led counselling programme on eye patch application for improvement of adherence to eye patch application and vision among children with amblyopia.Material and methods A randomised control trial was done at the paediatric clinic in the eye outpatient department of a tertiary care institute in North India. …”
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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…This systematic review and meta-analysis evaluated the effectiveness and safety of these agents in preventing ROP.Methods and Analysis A systematic search was conducted in Embase, MEDLINE and CENTRAL databases. Eight randomised controlled trials involving 1101 preterm infants were included. …”
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What is the evidence for efficacy of advance care planning in improving patient outcomes? A systematic review of randomised controlled trials by Chetna Malhotra, Mahham Shafiq, Ada Portia Macarubbo Batcagan-Abueg

“…Objectives To conduct an up-to-date systematic review of all randomised controlled trials assessing efficacy of advance care planning (ACP) in improving patient outcomes, healthcare use/costs and documentation.Design Narrative synthesis conducted for randomised controlled trials. …”
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East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol by Michael Doherty, Roshan das Nair, Ana Valdes, Reuben Ogollah, Paul Greenhaff, Bonnie Millar, Michelle Hall, Amy Fuller, Polykarpos Angelos Nomikos, David A Walsh, A Abhishek

“…The feasibility and acceptability of the intervention, and feasibility of undertaking a future cohort randomised controlled trial (RCT) will be explored.Methods and analysis In phase 1, we will develop a training programme for nurses and evaluate the fidelity and acceptability of the non-pharmacological element of the intervention. …”
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Research on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial by Mengpei Xu, Ying Wu, Yaqing Zhou, Zhongmei Lv, Wei Chen, Jingjing Fan

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Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch in context by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

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Frameworks for the design and reporting of anaesthesia interventions in perioperative clinical trials by Karen D. Coulman, Lucy Elliott, Natalie S. Blencowe, Joyce Yeung, Leila Rooshenas, Robert J. Hinchliffe, Ronelle Mouton, Eric Albrecht, David Bosanquet, Kariem El-Boghdadly, Gudrun Kunst, Mandeep Phull, Helen Galley, Ben Gibbison, Suzanne Harrogate, Anna Simpson, Jasmeet Soar, Michael Gillies, Mr James Glasbey, Sina Grape, David Hewson, Simon Howell, Louise Savic, Alan MacFarlane, Brendan McGrath, Ciara O'Donnell, Jon Silversides, Katrina Pirie, Andrew Toner

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Comment on “A Better Way to Decrease Knee Swelling in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial” by Max Broere, Yoshka van der Tuijn, Ingrid A. Szilagyi, Erin M. Macri

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Examining physical training versus physical and mental training programmes in Swimrun semi-professional athletes: A randomised, controlled, trial by Francesco Chirico, Giuseppe Ferrari, Giuseppina Rasà

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Traditional Chinese medicine injections for heart failure: a protocol for systematic review and network meta-analysis of randomised controlled trials by Shanshan Lin, Qingyang Shi, Fengwen Yang, Xianliang Wang, Jingyuan Mao

“…The purpose of this study is to assess and compare the effect of different TCMIs for HF using network meta-analysis (NMA) and further provide references for clinical decision-making.Methods and analysis The clinical randomised controlled trials (RCTs) and meta-analyses of TCMIs for treating HF will be searched in the relevant database, including PubMed, EMBASE, Cochrane Library (No. 2 of 2020), Chinese BioMedical Literature Database, China National Knowledge Infrastructure, Wan Fang Database and Chinese Scientific Journal Database from inception to 29 February 2020. …”
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Role of Platelet-rich Plasma in Unexplained Recurrent Implantation Failure – A Systematic Review and Meta-analysis of Randomised Control Trials by Harpreet Kaur, Meenakshi Meenu, Shivam Pandey, Anil Chauhan, Mishu Mangla

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Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial by David Evans, Francesco Negro, Michail Arvanitidis, Eduardo Martinez-Valdes, Ragul Selvamoorthy, Patricio Pincheira

“…Newly developed training protocols that employ visual feedback with specialised devices offer controlled management of loads, speeds and forces across the full range of motion, potentially providing greater benefits.Objective This protocol outlines a randomised controlled trial designed to compare the effects of a visuomotor torque feedback (TF) protocol with a traditional EE protocol on the rehabilitation of PT over a 6-week period. …”
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