Prevention Of Breast and Endometrial cancer using Total Diet Replacement (PROBE-TDR) trial: protocol for a randomised controlled trial by Robert Clarke, Emma J Crosbie, Basil G Issa, John Belcher, Helen Clarke, Anthony Howell, Michelle Harvie, Hannah Harrison, Cheryl Lombardelli, Suzanne Krizak, Katharine Sellers, Yit Y Lim, Caroline Parkin, Shruthi Patel, Anthony J Maxwell, Julie Wisely, Sacha J Howell

“…Results will be published in peer-reviewed journals, presented at conferences and shared with trial participants.Trial registration number International Standard Randomised Controlled Trial Number Registry (ISRCTN15358157).…”
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Effects of a 16-week dance intervention on loneliness and self-esteem in left behind children: a randomised controlled trial by Xiaolin Li, Qian Yang, Jiayi Long, Linghui Zhou, Chunxia Lu, Zhenqian Zhou, Ming Zeng, Weixin Dong

“…Therefore, this study validated the effectiveness of a dance intervention on loneliness and self-esteem in left-behind children through a 16-week randomised controlled trial. Stratified sampling was used to select one primary school from each of the 14 cities in Hunan Province, with a maximum of 100 children recruited from each primary school. …”
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Effect of traditional Chinese exercise on abnormal lipid metabolism in patients with atherosclerosis: a protocol for meta-analysis of randomised controlled trials by Chen Wang, Peizhen Zhang, Yuting Yang

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Does improving sleep lead to better mental health? A protocol for a meta-analytic review of randomised controlled trials by Georgina Rowse, Alexander J Scott, Thomas L Webb

“…One way to evaluate this assertion is to examine the extent to which interventions that improve sleep also improve mental health.Method and analysis Randomised controlled trials (RCTs) describing the effects of interventions designed to improve sleep on mental health will be identified via a systematic search of four bibliographic databases (in addition to a search for unpublished literature). …”
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Evaluation on the effectiveness on the implementation of WHO caregiver skills training (CST) programme in Hong Kong: a randomised controlled trial protocol by Wai-Ching Paul Wong, Siu-Lun Chow

“…The WHO-CST aims to enhance the caregiver skills of parents of children with potential autism spectrum disorders (ASD) and/or developmental delays.Methods and analysis In this study, 130 eligible caregiver–child dyads were recruited and randomly assigned to the experimental and wait-list-control groups. A randomised controlled trial design was adopted to compare the changes between the two groups regarding caregivers’ skills, knowledge and practices when interacting with their children with impairments due to ASD. …”
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The efficacy of acupuncture in relieving postoperative pain in patients with low simple anal fistula: Protocol of a prospective, randomised, controlled trial. by Min Yang, De Zheng, Xingtao Jin, Huili Tang, Weiwei Cao, Qianqian Ye, Yin Qu, Zubing Mei

“…<h4>Methods</h4>This single-centre, patient-blinded, assessor-blinded, placebo-controlled randomised controlled trial (RCT) will be conducted at a tertiary referral hospital. …”
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Controlled ovarian hyperstimulation with or without letrozole for fertility preservation in breast cancer patients: study protocol for a randomised controlled trial by Ping Li, Kun Wang, Qi Fan, Peng Sun, Yuhua Shi, Yanqiu Xie, Weifen Deng, Jiajing Kang

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The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials by Sogand Tavakoli, Mohammad Reza Amini, Reyhaneh Rabiee, Marieh Salavatizadeh, Mostafa Afsharianfar, Moein Askarpour, Azita Hekmatdoost

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Effect of a multispecies probiotic on reducing the incidence of antibiotic-associated diarrhoea in children: a protocol for a randomised controlled trial by Hania Szajewska, Jan Łukasik

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Effectiveness of progesterone supplementation in women presenting low progesterone levels on the day of frozen embryo transfer: a randomised controlled trial by Quang Thanh Le, Thi Minh Chau Le, Khue Tu Duong, Quoc Anh Nguyen, Phuc Thinh Ong, Thi Hong Nhung Nguyen, Thi Cam Thu Thai, Matheus Roque, Carlo Alviggi

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Using systems mapping within the process evaluation of a randomised controlled trial of the ACE active ageing programme in England and Wales by Helen Hawley-Hague, Colin Greaves, Diane Crone, Afroditi Stathi, Nick Cavill, Amy Davies, Katie E Chatwin, Zsofia Szekeres, Janet Withall, Janice Thompson

“…In this paper, we describe an innovative approach to using system mapping as part of the process evaluation of a randomised controlled trial of the Active, Connected, Engaged (ACE) community-based active ageing programme.Method Ten participatory workshops were held across three of the ACE sites (Cardiff, Stoke-on-Trent and Manchester, UK). …”
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Effects of message framing on self-management behaviour among patients with type 2 diabetes: a randomised controlled trial protocol by Xin Zhang, Feng Li, Hui Guo, Yue Pang, Yandi Liu, Ruitong Gao, Xiaoqian Lian, Tianyue Yu, Lanyu Zhu

“…The purpose of our research is to potentially explore the effectiveness of diabetes education based on message framing on the self-management behaviour.Methods and analysis A single-blind, three-arm randomised controlled trial involving 84 participants will be conducted. …”
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Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5).Discussion This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. …”
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Public and patient involvement (PPI) in the design, execution and dissemination of a trial: the BISTRO trial by David Coyle, Paula Ormandy, Nancy Fernandes da Silva, Simon Davies

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Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta... by Leiling Liu, Zhiqi Li, Wenrui Ye, Pu Peng, Yurong Wang, Luqing Wan, Jiangnan Li, Mei Zhang, Yihua Wang, Runqi Liu, Danyan Xu, Jingjing Zhang

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Are school-based violence prevention interventions inclusive and effective for children with disabilities? A systematic review of global evidenceResearch in context by Emily Eldred, Karen Devries, Anja Zinke-Allmang, Rizwana Mallick, Waliyah Mughis, Lena Morgon Banks, Amiya Bhatia

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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled trial by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…Therefore, exploring strategies to minimise laxative volume and improve patient tolerance and adherence is imperative to ensure optimal bowel preparation quality.Methods and analysis This study is a two-arm, single-blinded, parallel-group randomised controlled trial designed to compare the efficacy of 2 L polyethylene glycol (PEG) combined with linaclotide with 4 L PEG in bowel cleansing. …”
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Effect of 12 weeks of selective cardiorespiratory endurance and plyometrics training on 800-meter rural collegiate athletes: a randomised controlled trial by Neeraj Kumar, Anand N. Badwe

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Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

“…Publicly funded randomised controlled trials (RCTs) often recruit participants at a slower than anticipated rate. …”
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Efficacy and safety of ciprofol versus propofol for induction of general anaesthesia or sedation: A systematic review and meta-analysis of randomised controlled trials by Abdallah Saeed, Mariam Elewidi, Ahmad Nawlo, Amr Elzahaby, Asmaa Khaled, Abdalla Othman, Mohamed Abuelazm, Basel Abdelazeem

“…Results: Nineteen randomised controlled trials were included in our analysis, with 2841 participants. …”
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