The engagement of healthcare providers in implementing the selfBACK randomised controlled trial – A mixed-methods process evaluation by Mette Jensen Stochkendahl, Barbara I Nicholl, Karen Wood, Frances S Mair, Paul Jarle Mork, Karen Søgaard, Charlotte DN Rasmussen

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Transplant Trial Watch by John M. O’Callaghan, John M. O’Callaghan, Simon R. Knight, Simon R. Knight

Subjects: “…randomised controlled trial…”
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Effect of environmental enrichment on relapse rates in patients with severe alcohol use disorder: protocol for a randomised controlled trial by Lila Barillot, Claudia Chauvet, Marc Besnier, Nematollah Jaafari, Marcello Solinas, Armand Chatard

“…Our EE will allow an enhancement of the standard intervention, and will combine several promising enrichment factors identified in the literature—physical activity, cognitive stimulation, mindfulness and virtual reality (VR).Methods and analysis A randomised controlled trial involving 135 participants receiving treatment for severe AUD will be conducted. …”
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A Randomised Controlled Trial Comparing Chemomechanical (Carie-Care™) Versus Conventional Caries Removal for Atraumatic Restorative Treatment by Saloni Gupta, Kalyana Chakravarthy Pentapati, Shashidhar Acharya

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Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

“…Introduction Steroids In caRdiac Surgery trial (SIRS) is a large international randomised controlled trial of methylprednisolone or placebo in patients undergoing cardiac surgery with the use of a cardiopulmonary bypass pump. …”
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Digital cognitive training in children with attention-deficit/hyperactivity disorder: a study protocol of a randomised controlled trial by Sally Richmond, Hannah Kirk, Kim Cornish, Mark A Bellgrove, Tori Gaunson, Meg Bennett

“…This study aims to assess the immediate and long-term efficacy of an attention training intervention in children with ADHD.Methods and analysis This study is a preregistered, parallel, double blind, randomised controlled trial. Participants will comprise 104 children with a diagnosis of ADHD aged 5–8 years 11 months. …”
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Nurse-led counselling programme on the adherence to eye patch application among children with amblyopia: a randomised control trial by Srishti Raj, Savleen Kaur, Mona Duggal, Shivani ­, Sushma Kumari Saini

“…Objective To assess the impact of the nurse-led counselling programme on eye patch application for improvement of adherence to eye patch application and vision among children with amblyopia.Material and methods A randomised control trial was done at the paediatric clinic in the eye outpatient department of a tertiary care institute in North India. …”
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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…This systematic review and meta-analysis evaluated the effectiveness and safety of these agents in preventing ROP.Methods and Analysis A systematic search was conducted in Embase, MEDLINE and CENTRAL databases. Eight randomised controlled trials involving 1101 preterm infants were included. …”
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What is the evidence for efficacy of advance care planning in improving patient outcomes? A systematic review of randomised controlled trials by Chetna Malhotra, Mahham Shafiq, Ada Portia Macarubbo Batcagan-Abueg

“…Objectives To conduct an up-to-date systematic review of all randomised controlled trials assessing efficacy of advance care planning (ACP) in improving patient outcomes, healthcare use/costs and documentation.Design Narrative synthesis conducted for randomised controlled trials. …”
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Research on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial by Mengpei Xu, Ying Wu, Yaqing Zhou, Zhongmei Lv, Wei Chen, Jingjing Fan

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Frameworks for the design and reporting of anaesthesia interventions in perioperative clinical trials by Karen D. Coulman, Lucy Elliott, Natalie S. Blencowe, Joyce Yeung, Leila Rooshenas, Robert J. Hinchliffe, Ronelle Mouton, Eric Albrecht, David Bosanquet, Kariem El-Boghdadly, Gudrun Kunst, Mandeep Phull, Helen Galley, Ben Gibbison, Suzanne Harrogate, Anna Simpson, Jasmeet Soar, Michael Gillies, Mr James Glasbey, Sina Grape, David Hewson, Simon Howell, Louise Savic, Alan MacFarlane, Brendan McGrath, Ciara O'Donnell, Jon Silversides, Katrina Pirie, Andrew Toner

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Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch in context by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

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Comment on “A Better Way to Decrease Knee Swelling in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial” by Max Broere, Yoshka van der Tuijn, Ingrid A. Szilagyi, Erin M. Macri

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Examining physical training versus physical and mental training programmes in Swimrun semi-professional athletes: A randomised, controlled, trial by Francesco Chirico, Giuseppe Ferrari, Giuseppina Rasà

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Role of Platelet-rich Plasma in Unexplained Recurrent Implantation Failure – A Systematic Review and Meta-analysis of Randomised Control Trials by Harpreet Kaur, Meenakshi Meenu, Shivam Pandey, Anil Chauhan, Mishu Mangla

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Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial by David Evans, Francesco Negro, Michail Arvanitidis, Eduardo Martinez-Valdes, Ragul Selvamoorthy, Patricio Pincheira

“…Newly developed training protocols that employ visual feedback with specialised devices offer controlled management of loads, speeds and forces across the full range of motion, potentially providing greater benefits.Objective This protocol outlines a randomised controlled trial designed to compare the effects of a visuomotor torque feedback (TF) protocol with a traditional EE protocol on the rehabilitation of PT over a 6-week period. …”
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Application of probiotics, prebiotics and synbiotics in patients with breast cancer: a systematic review and meta-analysis protocol for randomised controlled trials by Wenjie Liu, Wenyao Cui, Xinrong Chen, Dan Duan, Maojun Chen

“…This protocol aims to explore the effectiveness and safety of probiotics, prebiotics and synbiotics in patients with breast cancer.Methods and analysis We will search the following electronic databases for relevant randomised controlled trials: PubMed, EMBASE, Cochrane Library and Web of Science. …”
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Baricitinib for the Management of SARS-CoV-2-Infected Patients: A Systematic Review and Meta-Analysis of Randomised Controlled Trials by Sivananthan Manoharan, Lee Ying Ying

“…To answer these questions, three databases known as ScienceDirect, PubMed/MEDLINE, and Scopus and other sources, such as preprint (medRxiv) and reference lists, were thoroughly searched. Four randomised controlled trials (RCTs) were included. Based on the meta-analysis, baricitinib statistically significantly reduced mortality with the risk ratio (RR) of RR = 0.74 [95% CI: 0.58 to 0.94; p=0.01] and moderately high heterogeneity, where I2 = 62% and p=0.05. …”
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Protocol for process evaluation of SMART Mental Health cluster randomised control trial: an intervention for management of common mental disorders in India by Anushka Patel, David Peiris, Pallab K Maulik, Graham Thornicroft, Shekhar Saxena, Sudha Kallakuri, Amanpreet Kaur, Siddhardha Devarapalli, Mercian Daniel, Beverley M Essue, Shashi Kant, D Praveen, Usha Raman, Rajesh Sagar, Ankita Mukherjee

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Time to intubation with McGrath™ videolaryngoscope versus direct laryngoscope in powered air-purifying respirator: a randomised controlled trial by Qing Yuan Goh, Sui An Lie, Zihui Tan, Pei Yi Brenda Tan, Shin Yi Ng, Hairil Rizal Abdullah

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