Methodological insights into intervention and outcomes in randomised controlled trials of herbal medicine for obesity: a scoping review by Janice Sue Wen Chan, Mei Siu Lau, Siti Hajar Muhamad Rosli, Siti Khadijah Mustapha Kamal, Wan Nurul Nadia Wan Seman, Nurul Hidayah Ali, Terence Yew Chin Tan, Ida Farah Ahmad, Puspawathy Krishnan, Marisa Khatijah Borhan, Ami Fazlin Syed Mohamed, Xin Yi Lim

“…Objectives: This scoping review aimed to gather information from herbal medicine anti-obesity randomised controlled trials (RCTs), analyse the methodologies and assess their alignment with international guidelines. …”
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Feasibility study of a randomised controlled trial of preoperative and postoperative nutritional supplementation in major lung surgery by Amelia Swift, Sebastian T Lugg, Babu Naidu, Nikolaos Efstathiou, Amy Kerr, Hazem Fallouh, Maninder Kalkat, Richard Steyn, Salma Kadiri, Ehab Bishay, Krishna Kholia, Venessa Rogers

“…Patients felt the questionnaires captured their experience of recovery from surgery well.Conclusion A large multicentre randomised controlled trial of nutritional intervention in major lung surgery is feasible and required to test clinical efficacy in improving outcomes after surgery.Trial registration number ISRCTN16535341.…”
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Cluster randomised controlled trial to examine medical mask use as source control for people with respiratory illness by Abrar Ahmad Chughtai, Chandini Raina MacIntyre, Yi Zhang, Quanyi Wang, Bayzidur Rahman, Haiyan Zhang, Holly Seale, Daitao Zhang, Yanhui Chu

“…Rationale Medical masks are commonly used by sick individuals with influenza-like illness (ILI) to prevent spread of infections to others, but clinical efficacy data are absent.Objective Determine whether medical mask use by sick individuals with ILI protects well contacts from related respiratory infections.Setting 6 major hospitals in 2 districts of Beijing, China.Design Cluster randomised controlled trial.Participants 245 index cases with ILI.Intervention Index cases with ILI were randomly allocated to medical mask (n=123) and control arms (n=122). …”
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Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial by Nick Shortt, Alex Semprini, Mark Weatherall, Richard Beasley, Irene Braithwaite, Angela Liu, Melanie McConnell, Joseph Singer, Darmiga Thayabaran, Abbie Copinga, Abigail Cadwallader, Ahmad Zareh, Aidan Kortegast, Al-Sheibani Saif, Alaina van Zyl, Alex Graham, Alice Liu, Alice Manch, Alison van Wyke, Amanda Barkley, Amy Zhuang, Andrew Mcglashen, Androulla Kotrotsos, Angela Blackwood, Angeline Day-Mesuré, Annabel Turley, Anne Lim, Anne Marie-Nimmo, Anstey Harsant, Anthony Roberts, Ashley Cronin, Barbara Mcrae, Blair Finlayson, Bob Kim, Brandon, Brendon Mcintosh, Brian Johnston, Carina Soeteman, Carla Mcinness, Carrol Newman, Cassie Butler, Catherine Hosler, Cathy Hight, Chantel Kissick, Charlotte Schimanski, Chau Ly, Cheryl Mabbett, Chris Wrapson, Christy Biju, Chuck Varghese, Claire Livingston, Corry Bezems, Danielle Stewart, Daryl Sayer, David Postlewaight, Deb Lawrence, Debora Ngny, Deborah Ellison, Debra Clutterback, Delphine Destrez, Diana Montelli, Dipika Parmar, Dixie Howard, Donnie Loh, Eddie See, Elda Lubbe, Eric Li, Evan Tan, Fiona Mclachlan, Fiona Srush, Fran Chen, Garth Mitchinson, Gina Azer-Iskander, Glenn Summerville, Grace O’conner, Grant Bell, Hayley Garvin, Helen Jarvie, Henriette Meyer, Ingrid Nickson, Ingrid Reed, Irene Nicks, Jackie Jamieson, Jacqui Brus, Jacqui Craw, James Westbury, Jan Green, Janet Downing, Jayne Lewis, Jenna Ludlow, Jenni Puckley, Jennifer Gerbes, Jenny Sparks, Jenny Wu, Jess Barton, Jessica Ensor, Jilly Alexander, Jim Sherborne, Joanna Topliss, Jordan Jeffray, Jordon Hinton, Joseph Tsou, Joy Birch, Julia Mcdonald, Julie Earwaker, Julie Lamb, Julie Summers, Kadyn Lowe, Kaleigh Mackel, Karen Rich, Karen Chen, Karen Wainman, Karena Hall, Kate Adams, Kate Griffin, Kayleigh Mackel, Kelly Burgess, Kelly Harvey, Kelly Shearer, Kelsi Burns, Kerry Dean, Kerry Oxenham, Kritika Singh, Lara Blaikie, Leanne Hall, Leanne Herbert, Leanne Hosking, Leanne Steele, Leigh Vaughan, Lesley Robertson, Levi Bian, Linda Herman, Linda Joe, Linda Southby, Lisa Josephs, Lisa Mitchell, Lorina Lu, Lorraine Brunton, Lucy Armstrong, Lynda Bell, Malinda Ouk, Malli Kotali, Marcus Liddle, Margaret Helms, Marion Gray, Mark Arundel, Mark Webster, Martin Boyle, Maryanne Smyth, Mate Hegedus-Gaspar, Matthew Grey, Maureen Raju, Melanie Wong, Michelle Hwang, Michelle Nawisielski, Michelle Speirs, Natascha Roughton, Navjot Kaw, Neha Chand, Nehad Kamel, Neville Puckey, Nicholas Tee, Nimmi Gnanasekaran, Nolan Mcrae, Noor Al-Rawe, Oliver Rew, Olivia Haslam, Outi Kolju, Palak Mehta, Patrick Lim, Peter Neal, Rachael Gerretzen, Rachael Munns, Rachel Yang, Rachelle Smith, Raksha Goundar, Rav Singh, Ravniel Singh, Rebecca Coley, Rebecca Hesom, Rebekah Beard, Reece Olsen, Renee Belling, Robyn Morrison, Roseanna Mcdonald, Ruby Willing, Saif Al-Sherbeni, Sally Purdie, Sam Betty, Sam Appleford, Samantha Fordham, Samit Patel, Sara Preston, Sarah Wallace, Sascha Ion, Shahlaa Al Salih, Sharon Sullivan, Shazeel Rauf, Sheryl Montgomerie, Shilpa Narain, Shirin Namjou, Shuji Zhang, Simerjeet Singh, Sjaani Stanley, Sonia Schwaum, Steve Jo, Sultana Zannat, Tanya Baker, Tyler Pornchaisuksiri, Utsav Sharma, Vicki Douglas, Victoria Rameke, Vincent Ho, Vioky Usher, Violet Harley, Vishwatej Gangapuri, Warren Greene, Wendy Parkes, William Gia, Wilma Gordon, Yalun Weng, Yasmin Razoki, Yolanda Savage, Zheng Li

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Efficacy and Adverse Effects of Atropine for Myopia Control in Children: A Meta-Analysis of Randomised Controlled Trials by ChunWen Chen, JingYan Yao

“…We selected randomised controlled trials (RCTs) that evaluated the efficacy of atropine for controlling myopia progression in children. …”
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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

“…The purpose is to identify the utility and efficacy of fMRI-guided microsurgery of AVMs in a large randomised controlled trial.Methods and analysis The study is a prospective, randomised controlled clinical trial. …”
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ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

“…We describe the protocol for the first ever randomised control trial of IVIG treatment for children with all-cause encephalitis.Methods and analysis 308 children (6 months to 16 years) with a diagnosis of acute/subacute encephalitis will be recruited in ∼30 UK hospitals and randomised to receive 2 doses (1 g/kg/dose) of either IVIG or matching placebo, in addition to standard treatment. …”
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Effectiveness of a pain science education programme in middle school students: a randomised controlled trial by Laura Menés Fernández, Isabel Salvat, Cristina Adillón

“…The primary aim of this study is to assess the effectiveness of the Pain Science Education programme called “Learning Pain” in improving the conceptualization of pain amongst 11–13-year-old children enrolled in their first year of middle school.Materials and methodsA randomised controlled trial with single-blind parallel groups was conducted. …”
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Preovulatory uterine flushing with saline as a treatment for unexplained infertility: a randomised controlled trial protocol by Lynne Moore, Jessica Lefebvre, Sarah Maheux-Lacroix, Marie-Ève Bergeron, Emmanuel Bujold, Sylvie Dodin

“…Our objective is to assess the efficacy of preovulatory uterine flushing with physiological saline for the treatment of unexplained infertility.Methods and analysis We will perform a randomised controlled trial based on consecutive women aged between 18 and 37 years consulting for unexplained infertility for at least 1 year. …”
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Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

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Chinese Herbal Medicine for Weight Management: A Systematic Review and Meta-Analyses of Randomised Controlled Trials by Ann Rann Wong, Angela Wei Hong Yang, Kangxiao Li, Harsharn Gill, Mingdi Li, George Binh Lenon

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Effect of breathing exercises with biofeedback on blood pressure in pre-hypertensive women: a randomised controlled trial by Afaf M. Botla, Reham S. Ebrahim, Soheir M. Elkosery, Ahmed M. Darwesh, Dina M.A. Mohamed

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Analysis of the Modified Rankin Scale in Randomised Controlled Trials of Acute Ischaemic Stroke: A Systematic Review by Aimie Nunn, Philip M. Bath, Laura J. Gray

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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

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Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol by Zhihong Fan, Shenghong Jia, Xin Zhou, Chao Li, Jiahao Shao, Xiaofeng Liu, Yitao Liao, Yenan Xu, Dandan He, Shixiang Wu, Xian Zhang

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The effect of a community-based health behaviour intervention on healthcare services use among people with type 2 diabetes in Nepal by Grish Paudel, Corneel Vandelanotte, M Mamun Huda, Padam Kanta Dahal, Lal Rawal

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Assessing the impact of educational methods on influenza vaccine uptake and patient knowledge and attitudes: a randomised controlled trial by Pei Lin Hu, Eileen Yi Ling Koh, Jolene Shi Han Tay, Valerie Xin-Bei Chan, Shermin Shi Min Goh, Sinead Zhen Wang

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Internet-based cognitive behavioural therapy for adults with tinnitus in the UK: study protocol for a randomised controlled trial by Peter M Allen, David M Baguley, Gerhard Andersson, Eldré W Beukes, Vinaya Manchaiah

“…It, furthermore, aims to establish whether there are subgroups of tinnitus sufferers for whom this iCBT intervention may be more suitable.Methods and analysis A two-armed randomised control trial—with a 1-year follow-up design—will be used to evaluate the effectiveness of iCBT on tinnitus distress. …”
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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…The trial aim is to determine whether parental touch prior to a painful clinical procedure provides effective pain relief in neonates.Methods and analysis This is a multicentre randomised controlled trial. A total of 112 neonates born at 35 weeks’ gestation or more requiring a blood test in the first week of life will be recruited and randomised to receive parental stroking either preprocedure or postprocedure. …”
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Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials by Jia Chen, Juan Liu, Yuan-yuan Ye, Ni-ka Chen, Ling Lin, Ya-zhen Liu, Ying Lang, Xun-jun Li, Xin-ju Yang, Xiao-jiang Jiang

“…Objective To evaluate the effectiveness of internet-based cognitive–behavioural therapy for insomnia (ICBT-i) in adults.Design A meta-analysis of ICBT-i.Data sources Systematic searches of randomised controlled trials of ICBT-i were performed in the PubMed, EMBASE, PsycINFO and Cochrane Library databases up to 19 June 2016.Review method 2 reviewers independently performed study selection, quality assessment and data extraction. …”
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