Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy in Sub-Saharan Africa: A scoping review. by Naa A Buxton-Tetteh, Shakti Pillay, Gugulabatembunamahlubi T J Kali, Alan R Horn

“…There were five studies recruiting at follow-up, five pilot studies, one randomised controlled trial, one case series, and 10 birth cohorts. …”
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Challenges for funders in monitoring compliance with policies on clinical trials registration and reporting: analysis of funding and registry data in the UK by Rachel L Knowles, Frances Rawle, Kam Pou Ha, Julia Mueller, Rosa Parker

“…Objectives To evaluate compliance by researchers with funder requirements on clinical trial transparency, including identifying key areas for improvement; to assess the completeness, accuracy and suitability for annual compliance monitoring of the data routinely collected by a research funding body.Design Descriptive analysis of clinical trials funded between February 2011 and January 2017 against funder policy requirements.Setting Public medical research funding body in the UK.Data sources Relevant clinical trials were identified from grant application details, post-award grant monitoring systems and the International Standard Randomised Controlled Trial Number (ISRCTN) registry.Main outcome measure The proportion of all Medical Research Council (MRC)-funded clinical trials that were (a) registered in a clinical trial registry and (b) publicly reported summary results within 2 years of completion.Results There were 175 grants awarded that included a clinical trial and all trials were registered in a public trials registry. …”
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Comparison of Goal Achievement during an Early, Intensive Nutrition Intervention Delivered to People with Upper Gastrointestinal Cancer by Telephone Compared with Mobile Applicatio... by Kate Furness, Catherine E. Huggins, Lauren Hanna, Daniel Croagh, Mitchell Sarkies, Terry P. Haines

“…This study is aimed at exploring whether the mode of nutrition intervention delivery affected participant goal achievement in a three-arm randomised controlled trial of early and intensive nutrition intervention delivered to upper gastrointestinal cancer patients. …”
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Long-term Double-J stenting is superior to short-term Single-J stenting in kidney transplantation. by Christiaan A J Oudmaijer, Kelly Muller, Erika van Straalen, Robert C Minnee, Diederik J A N Kimenai, Marlies E J Reinders, Jacqueline van de Wetering, Jan N M IJzermans, Turkan Terkivatan

“…<h4>Methods</h4>We performed a non-blinded single-centre randomised controlled trial in an academic hospital. Kidney transplant recipients were randomised to either a Single-J stent or a Double-J stent, removed according to respective protocols. …”
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Effectiveness of a resilience, gender equity and mental health group intervention for young people living in informal urban communities in North India: a cluster randomized control... by Varadharajan Srinivasan, Miguel San Sebastián, Samson Rana, Pooja Bhatt, Greg Armstrong, Smita Deshpande, Kaaren Mathias

“…Methods This cluster randomised controlled trial used an analytic sample of 476 adolescents and young adults aged 11–25 years from randomised clusters in urban Dehradun, India. …”
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Measuring the duration of kangaroo mother care for neonates: a scoping review by Moffat Nyirenda, Cally J Tann, Melissa M Medvedev, Joy Lawn, Eva Loucaides, Victor Spector Tumukunde

“…We conducted a scoping review of KMC duration measurement methods and assessed their validation.Design Scoping review in accordance with Joanna Briggs Institute guidance for conducting scoping review.Data sources MEDLINE, Embase, Cochrane Library, PsycINFO, African Index Medicus, Latin American and Caribbean Health Sciences Literature, ClinicalTrials.gov, International Clinical Trials Registry Platform, International Standard Randomised Controlled Trial Number Registry, Medrxiv and OpenGrey were searched through November 2022.Eligibility criteria for selecting studies Publications with primary data on KMC duration were included. …”
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Development and feasibility of an mHealth intervention for psychoeducational support of Nigerian women diagnosed with breast cancer undergoing chemotherapy: A pilot randomized cont... by Oluwadamilare Akingbade, Ka Yi Hong, Oluwabukola Sharon Ayo, Adetutu Sefinat Alade, Moshood Akinwumi Lawal, Ibironke Elizabeth Somoye, Victoria Adediran, Olamide Sado, Ka Ming Chow

“…<h4>Methods</h4>A multi-centre, assessor-blinded, parallel-group pilot randomised controlled trial (RCT) was conducted at Lagos State University Teaching Hospital (LASUTH) and Lagos University Teaching Hospital (LUTH). …”
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Early childhood constraint therapy for sensory/motor impairment in cerebral palsy: a randomised clinical trial protocol by Garey Noritz, Olena Chorna, Jill Heathcock, Alexandra Key, Helen Carey, Ellyn Hamm, Mary Ann Nelin, Micah Murray, Amy Needham, James C Slaughter, Nathalie L Maitre

“…Constraint-induced movement therapy (CIMT) is one of the few effective neurorehabilitative strategies shown to improve upper extremity motor function in adults and older children with CP, potentially overcoming developmental disregard.Methods and analysis This study is a randomised controlled trial of children 12–24 months corrected age studying the effectiveness of CIMT combined with motor and sensory-motor interventions. …”
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Sleep duration in adolescence buffers the impact of childhood trauma on anxiety and depressive symptoms by Toni Coote, Emma Barrett, Lucinda Grummitt

“…Methods Data were drawn from the baseline assessment of a randomised controlled trial of a mental health prevention program. …”
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Pilot Trial of the Reboot Online Program: An Internet-Delivered, Multidisciplinary Pain Management Program for Chronic Pain by Regina Schultz, Jessica Smith, Jill M. Newby, Tania Gardner, Christine T. Shiner, Gavin Andrews, Steven G. Faux

“…Future investigations will focus on conducting a randomised controlled trial of this innovative and promising treatment for chronic pain. …”
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Medication following bariatric surgery for type 2 diabetes mellitus (BY-PLUS) study: rationale and design of a randomised controlled study by Alexander Dimitri Miras, Carel le Roux, Alexis Sudlow, Ricardo Vitor Cohen, Hassan Kahal, Dimitri J Pournaras, Jill Townley, Helen Heneghan

“…Long-term studies suggest that although glycaemic control remains good, only 20%–40% of patients will maintain remission according to the American Diabetes Association criteria.Purpose This trial aims to examine the safety and efficacy of combining Roux-en-Y gastric bypass or sleeve gastrectomy with goal-directed medical therapy to improve long-term glycaemic control of T2DM.Methods and analysis This prospective, open-label multicentre randomised controlled trial (RCT) will recruit 150 patients with obesity and T2DM from tertiary care obesity centres. …”
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A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT) by Rebecca Watson, Kim A Wright, Nigel Reed, Barney Dunn, Emily Widnall, Kalliopi Demetriou, Laura Warbrick, Katie Marchant, Nicole Geschwind, Isabella Magner-Parsons, Rachel Barter

“…Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A semi-structured qualitative interview design was used, with data analysed using the framework approach.Participants 20 participants with anhedonic depression who had received up to 20 sessions of ADepT, sampled from a pilot randomised controlled trial of ADepT versus Cognitive Behavioural Therapy (CBT).Setting A primary care psychological therapy clinic in Devon, UK, with interviews occurring between May 2018 and February 2020.Results Participants found the wellbeing focus of ADepT acceptable. …”
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Misuse of Statistical Methods in 10 Leading Chinese Medical Journals in 1998 and 2008 by Shunquan Wu, Zhichao Jin, Xin Wei, Qingbin Gao, Jian Lu, Xiuqiang Ma, Cheng Wu, Qian He, Meijing Wu, Rui Wang, Jinfang Xu, Jia He

“…Many mistakes were found in the randomised controlled trial (56.3% in 1998; 67.9% in 2008), non- randomised clinical trial (57.3%; 58.6%), basic science study (72.9%; 65.5%), case study or case series study (48.4%; 47.2%), and cross-sectional study (57.1%; 44.2%). …”
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Economic evaluation of Maternal Depression Treatment in HIV (M-DEPTH) for perinatal depression among women living with HIV in Uganda: a cost-effectiveness analysis by Ryan McBain, Adeyemi Okunogbe, Rhoda K Wanyenze, Violet Gwokyalya, Glenn Wagner

“…Objective We conducted a cost-effectiveness analysis of an evidence-based collaborative care model for treatment of perinatal depression among women living with HIV in Uganda.Design Maternal Depression Treatment in HIV (M-DEPTH) is a cluster randomised controlled trial implemented from July 2019 to August 2023, during which 391 pregnant women with mild-to-severe depressive symptoms were randomised to receive stepped care for depression (M-DEPTH: behavioural and pharmacological treatments) or care as usual (CAU: hospital referral for severe cases), at one of eight public health facilities in Uganda.Methods We implemented time-driven, activity-based costing to determine the economic cost of M-DEPTH from a societal perspective, compared with CAU. …”
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Adapting and Implementing a Blended Collaborative Care Intervention for Older Adults with Multimorbidity: Quantitative and Qualitative Results from the ESCAPE Pilot Study by Josefine Schulze, Dagmar Lühmann, Jonas Nagel, Cornelia Regner, Christine Zelenak, Kristina Bersch, Christoph Herrmann-Lingen, Matthew M. Burg, Birgit Herbeck-Belnap

“…Next steps include launching the ESCAPE trial, a large randomised-controlled trial across different European healthcare systems and developing strategies to facilitate PCP involvement.…”
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The PainSMART project: Protocol for a research program on effectiveness, mechanisms of effect and patient-practitioner experiences of the PainSMART-strategy as an adjunct to usual... by Richard Thompson, Maria Fors, Ann-Sofi Kammerlind, Pia Tingström, Allan Abbott, Kajsa Johansson

“…<h4>Methods</h4>The PainSMART-project is a research program with a collective suite of studies utilising mixed methods, centred around a randomised controlled trial (ClinicalTrials.gov NCT06187428). …”
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Retention in the Bukhali trial in Soweto, South Africa: a qualitative analysis using self-determination theory by Shane A Norris, Stephen Lye, Catherine E Draper, Nosibusiso Tshetu, Nokuthula Nkosi

“…To address this gap, this study aimed to qualitatively examine retention in the Bukhali randomised controlled trial, from the perspective of trial participants and staff, through the lens of self-determination theory (SDT). …”
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Challenges of Assessing Maltreated Children Coming into Foster Care by Rachel Pritchett, Harriet Hockaday, Beatrice Anderson, Claire Davidson, Christopher Gillberg, Helen Minnis

“…An ongoing randomised controlled trial in Glasgow, Scotland, recruiting infants entering foster care, provides a unique opportunity to explore some of the issues which need to be considered when assessing these children. …”
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Protocol for a feasibility study evaluating a supported self-management intervention for stroke survivors with aphasia (StarStep study) by Faye Wray, Madeline Cruice, Ian Kellar, Anne Forster

“…Feasibility data will inform decision-making regarding progression to a future definitive cluster randomised controlled trial to evaluate the effectiveness of the intervention. …”
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Implementing injury prevention training in youth handball (I-PROTECT) in Sweden: study protocol for a cluster randomised trial by Per Nilsen, Alex Donaldson, Eva Ageberg, Sofia Bunke, Jennie Linnéll, Karin Moesch, Karolina Lucander, Axel Ström, Robert Wedberg, Per Ekberg

“…Within the I-PROTECT research project, the specific aim of this study is to investigate the implementation of the end-user-targeted I-PROTECT programme.Methods and analysis This pragmatic two-armed cluster randomised controlled trial is conducted collaboratively with the Swedish Handball Federation that has overall responsibility for handball in Sweden. …”
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