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381
Nutrigenomics: Definitions and Advances of This New Science
Published 2014-01-01“…Hence, Nutrigenomics corresponds to the use of biochemistry, physiology, nutrition, genomics, proteomics, metabolomics, transcriptomics, and epigenomics to seek and explain the existing reciprocal interactions between genes and nutrients at a molecular level. …”
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382
Characterizing the omics landscape based on 10,000+ datasets
Published 2025-01-01“…In this study, we investigate over ten thousand datasets to understand how proteomics, metabolomics, lipidomics, transcriptomics, and microbiome data vary in specific data characteristics. …”
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383
The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases
Published 2015-01-01“…However recent insights in the proteomics of diverse tissular cells have revealed that under stressful conditions they have a significant potential to initiate, coordinate, and perpetuate autoimmune processes, in many cases, ruling over the adaptive immune response cells; this ruling potential can also be confirmed by observations in several genetically manipulated animal models. …”
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384
Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus
Published 2017-01-01“…This review summarizes the various sources, proteomics, biological roles, adverse effects, and medical applications of melittin and its mechanism of action in combating DM.…”
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385
Role of New Biomarkers: Functional and Structural Damage
Published 2013-01-01“…Innovative technologies such as genomics and proteomics have contributed to the discovery of new biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys C), kidney injury molecule-1 (KIM-1), interleukin-18 (IL-18), and liver-type fatty acid binding protein (L-FABP). …”
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386
Application of Metabolomics in Thyroid Cancer Research
Published 2015-01-01“…Beside genomics, transcriptomics, and proteomics, metabolomic approach emerges as the most downstream attitude reflecting phenotypic changes and alterations in pathophysiological states of biological systems. …”
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387
Machine learning and multi-omics in precision medicine for ME/CFS
Published 2025-01-01“…In this review, we explore how machine learning and multi-omics (genomics, transcriptomics, proteomics, and metabolomics) can transform precision medicine in ME/CFS research and healthcare. …”
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388
How energy determines spatial localisation and copy number of molecules in neurons
Published 2025-02-01“…We combined our own data and experimental reports from five other large-scale mRNA and proteomics screens, comprising more than ten thousand molecular species to reveal the underlying computational principles of molecular localisation. …”
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389
Antimicrobial proteins from oyster hemolymph improve the efficacy of conventional antibiotics.
Published 2025-01-01“…Effective HPE concentrations are comparable to AMPPs currently approved for use or in clinical trials pipelines. Proteomics analysis of HPE identified a number of proteins including abundant known AMPPs. …”
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390
Results from an Australopithecus africanus dental enamel fragment confirm the potential of palaeoproteomics for South African Plio-Pleistocene fossil sites
Published 2025-02-01“…Palaeoproteomics can help improve our understanding of taxonomic variation, as demonstrated by the recently generated proteome of Paranthropus specimens from Swartkrans. …”
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391
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology
Published 2025-01-01“…We used immunohistochemical and biochemical analysis along with single-cell spatial omics and bulk proteomics to explore the impact of the ApoeCh variant on AD pathological development and the brain’s response to plaques and tau. …”
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392
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393
Multi-omics approach in tea polyphenol research regarding tea plant growth, development and tea processing: current technologies and perspectives
Published 2022-05-01“…These new technologies combining genomics, metagenomics, transcriptomics, proteomics and/or metabolomics can pave a new avenue to address fundamental questions regarding polyphenol formation and changes in tea plants and products. …”
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394
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395
Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity?
Published 2016-01-01“…Collective findings demonstrated that exosomes from HIV-infected subjects share many commonalities with Human Immunodeficiency Virus Type I (HIV-1) particles in terms of proteomics and lipid profiles. These observations postulated that HIV-resembled exosomes may contribute to HIV pathogenesis. …”
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396
Histopathological characterization of skin and muscle lesions induced by lionfish (Pterois volitans) venom in a murine experimental model
Published 2025-01-01“…Methods: In this study, we characterized the 24-hour histopathological effects of lionfish venom in a mouse experimental model by testing the main fractions obtained by size exclusion-HPLC. By partial proteomics analysis, we also correlated these in vivo effects with the presence of some potentially toxic venom components. …”
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397
Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
Published 2015-01-01Get full text
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398
Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma
Published 2025-01-01“…Through in vitro and in vivo experiments, we confirmed that CDKN3 silencing significantly inhibited the proliferative capacity of LGG cells. Proteomics revealed that CDKN3 can bind ARG1 and inhibite the intracellular arginase activity. …”
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399
Growth Differentiation Factor 15 and Risk of Death in Haemodialysis Patients
Published 2023-01-01“…Measurements were performed using the Proseek Multiplex Cardiovascular disease panels (Olink Proteomics AB) and validated using the Elecsys GDF-15 electrochemiluminescence immunoassay on a Cobas E801 analyzer (Roche Diagnostics). …”
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400
Propionate metabolism in Desulfurella acetivorans
Published 2025-02-01“…However, activities of the methylcitrate cycle enzymes could not be detected in extracts of propionate-grown cells, and experiments with [U-13C3]propionate and comparative proteomic analysis of acetate- and propionate-grown cells suggested that the methylcitrate cycle is not active during propionate growth. …”
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