Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota by Lianglan Li, Qiufen Mo, Yi Wan, Yuanhao Zhou, Weiqin Li, Weifen Li

“…Abstract Background Endogenous antimicrobial peptides and proteins are essential for shaping and maintaining a healthy gut microbiota, contributing to anti-inflammatory responses and resistance to pathogen colonization. …”
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The effect of drought stress on Pinellia ternata in terms of physiology and aquaporin genes after Arbuscular mycorrhizal fungal inoculation by Shuang Li, Yajun Liu, Han He, Yike Xu, Xiaochun Sun, Wenjing Huang

“…Under drought stress, P. ternata adapted to drought by accumulating osmotic regulatory substances such as proline and soluble proteins and increasing chlorophyll content. In addition, Mycorrhizal P. ternata also exhibited high activities of peroxidase, superoxide dismutase, and catalase under drought conditions, improving the response of the antioxidant system. …”
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Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response by Sophie C. van der Horst, Leonie Kollenstart, Amandine Batté, Sander Keizer, Kees Vreeken, Praveen Pandey, Andrei Chabes, Haico van Attikum

“…While several factors are known to act in this response, the full repertoire of proteins involved remains largely elusive. Here, we develop Replication-IDentifier (Repli-ID), which allows for genome-wide identification of regulators of DNA replication in Saccharomyces cerevisiae. …”
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Foreword—Breaking barriers in chemical biology: the innovative tour de force of the ChemBio GDR by Lopez, Marie, Mileo, Elisabetta, Defrancq, Eric, Delmas, Agnès,  Vauzeilles, Boris, Guianvarc’h, Dominique, Biot, Christophe

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PyBootNet: a python package for bootstrapping and network construction by Shayan R. Akhavan, Scott T. Kelley

“…Background Network analysis has emerged as a tool for investigating interactions among species in a community, interactions among genes or proteins within cells, or interactions across different types of data (e.g., genes and metabolites). …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…When these compounds were docked on to Bax, Caspase-3 Caspase-9 and Cox-2, the proteins integral to the mitochondrial apoptotic pathway, using PyRX software, the docking score was in the range from − 4 to -6.9 kcal/mol. …”
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Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. by Danelle S Eto, Tiffani A Jones, Jamie L Sundsbak, Matthew A Mulvey

“…Uropathogenic Escherichia coli (UPEC), the primary causative agent of urinary tract infections, typically express filamentous adhesive organelles called type 1 pili that mediate both bacterial attachment to and invasion of bladder urothelial cells. Several host proteins have previously been identified as receptors for type 1 pili, but none have been conclusively shown to promote UPEC entry into host bladder cells. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…MAGEA4 interacts with proteins including Miz-1, p53, and RAD18, participating in gene transcription regulation and DNA damage repair. …”
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Advances in antiviral strategies targeting mosquito-borne viruses: cellular, viral, and immune-related approaches by Ayyaz Khan, Zakirullah, Shahid Wahab, Seong-Tshool Hong

“…It also highlights recent advances in antiviral strategies targeting host factors such as lipid metabolism, ion channels, and proteasomes, as well as viral targets like NS2B-NS3 proteases and nonstructural proteins. Additionally, it explores immunomodulatory therapies to enhance antiviral responses and emphasizes the potential of drug repurposing, bioinformatics, artificial intelligence, and deep learning in identifying novel antiviral candidates. …”
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Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis by Juan Hu, Qiao Li, Shiqiu Jiang, Yingying Deng, Lan Yang, Mengyu Du, Shuxuan He, Fuxing Xu, Chaoying Yan, Wei Gao, Yansong Li, Yaomin Zhu

“…In this research, the study delved into the expression levels of cuproptosis-associated proteins FDX1, LIAS, and DLAT, as well as the copper content in both type 2 diabetes mellitus (T2DM) mice and primary neuronal cells exposed to high glucose and palmitic acid (HG/Pal). …”
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Unraveling the function of TSC1-TSC2 complex: implications for stem cell fate by Shuang Wang, Ruishuang Ma, Chong Gao, Yu-Nong Tian, Rong-Gui Hu, Han Zhang, Lan Li, Yue Li

“…These genes produce proteins that regulate mTORC1 activity, essential for cell function and metabolism. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Case studies highlight the application of computational techniques in AD therapeutics, including the suppression of crucial proteins implicated in disease progression and the repurposing of existing drugs for AD management. …”
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Nanofertilizers benefited maize to cope oxidative stress under saline environment by Abbas Shoukat, Zulfiqar Ahmad Saqib, Allah Nawaz, Kashif Zulfiqar Amir, Ilyas Ahmad, Ali Hamza, Karl Hermann Mühling

“…Higher proline content, proteins, relative water and chlorophyll content in plants treated with nano fertilizers demonstrated improved osmoregulation, metabolic homeostasis as well as maintaining water balance and photosynthetic efficiency under stress conditions. …”
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Development of an analytical method for the simultaneous determination of 22 Polycyclic Aromatic Hydrocarbons (PAHs) in maternal and umbilical cord blood by Swiha, Stéphanie, Pichon, Valérie, Fournier, Thierry, Gil, Sophie, Delaunay, Nathalie

“…Then, to break any interactions between PAHs and serum proteins, a precipitation step prior to solid-phase extraction was optimized using a design of experiments. …”
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Differential expression and localization of expansins in Arabidopsis shoots: implications for cell wall dynamics and drought tolerance by Darina Balkova, Katerina Mala, Jan Hejatko, Jan Hejatko, Klara Panzarova, Lamis Abdelhakim, Barbora Pleskacova, Marketa Samalova, Marketa Samalova

“…Expansins are cell wall-modifying proteins implicated in plant growth and stress responses. …”
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Advances in growth factor-containing 3D printed scaffolds in orthopedics by Longwen Zhan, Yigui Zhou, Ruitang Liu, Ruilong Sun, Yunfei Li, Yongzheng Tian, Bo Fan

“…This paper aims to summarize the research progress of 3D printed scaffolds containing growth factors in orthopedics in recent years and summarize the use of different growth factors in 3D scaffolds, including bone morphogenetic proteins, platelet-derived growth factors, transforming growth factors, vascular endothelial growth factors, etc. …”
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Platycodon grandiflorum-derived extracellular vesicles suppress triple-negative breast cancer growth by reversing the immunosuppressive tumor microenvironment and modulating the gu... by Min Yang, Jia Guo, Jinxian Li, Shuyue Wang, Yuan Sun, Ying Liu, Yinghua Peng

“…The PGEVs were isolated by ultracentrifugation and sucrose gradient centrifugation method and contained adequate functional components such as proteins, lipids, RNAs and active molecules. PGEVs exhibited remarkable stability, tolerating acidic digestion and undergoing minimal changes in simulated gastrointestinal fluid. …”
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Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities by Thunchanok Yaikhan, Monwadee Wonglapsuwan, Nuntiya Pahumunto, Natakorn Nokchan, Rawee Teanpaisan, Komwit Surachat

“…Among the 12,598 orthologous proteins, we identified 910 core genes and 10,169 accessory genes. …”
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Comprehensive genome-wide analysis of ARF transcription factors in orchardgrass (Dactylis glomerata): the positive regulatory role of DgARF7 in drought resistance by Miaoli Wang, Wen Liu, Guangyan Feng, Gang Nie, Zhongfu Yang, Feixiang Hao, Linkai Huang, Xinquan Zhang

“…Phylogenetic analysis with multispecies of ARF proteins indicated that the ARFs exhibit a relatively conserved evolutionary path. …”
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Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions by Walrant, Astrid, Tazi, Farah, Khemaissa, Sonia, Sagan, Sandrine

“…It separates the external environment from the cell interior and is composed of thousands of different lipids, proteins, and sulfated carbohydrates, all arranged in a complex and dynamic manner and at various length scales. …”
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