PPIH is a novel diagnostic biomarker associated with immune infiltration in cholangiocarcinoma by Jun Ye, Zhitao Chen, Chuan Zhang, Rui Xie, Haini Chen, Peng Ren

“…Results Our findings indicate that overexpression of PPIH mRNA in CHOL is associated with poor prognosis, with increased PPIH protein levels observed in CHOL tissues. Furthermore, PPIH expression showed a positive correlation with TP53 mutations. …”
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Integrated analysis of dermatomyositis reveals heterogeneous immune infiltration and interstitial lung disease-associated endotype by Xinzhi Xu, Tianwen Qiu, Kexin Sun, Xue Han, Junxia Huang, Xiuyuan Wang, Jianchao Ge, Ji Yang

“…Transcriptomic data from skin samples was utilized to assess immune infiltration and investigate the correlation between protein and mRNA levels of biomarkers. Additionally, the prognostic value and clinical significance of identified biomarkers were validated through follow-up studies of DM patients and immunofluorescence analysis of skin tissues. …”
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Optimized production and antiviral activity evaluation of recombinant chicken interferon-alpha using an improved Baculovirus expression system by Yuxia Zhang, Wenwen Dong, Feng Li, Kai Meng, Guiming Li, Xiaoyuan Yuan

“…A recombinant bacmid carrying two copies of the chIFN-α gene was successfully constructed. The chIFN-α protein was obtained using the modified baculovirus expression system, and exhibited anti-vesicular stomatitis virus (VSV) activity of up to 5.0 × 106 IU/ml. …”
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Insights into selection and application of carbohydrate-based carriers for microencapsulation: Stability and functional properties of maltodextrin, gum Arabic, and β-cyclodextrin i... by Pegah Mehrali, Seyed Hadi Peighambardoust, Amir Akbarmehr, Khashayar Sarabandi

“…Protein from tea flower pollen (TFP) was extracted and hydrolyzed to achieve polypeptides. …”
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Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis by Feng Si, Qian Wang, Fei Chen, Xiangdong Lu

“…CCK-8 was applied to analyze cell toxicity and proliferation. qRT-PCR and western blot were used to measure RNA and protein expressions, respectively. Cell cycle and cell apoptosis were determined by flow cytometry assay. …”
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Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing fact... by Ilkay Celik Gulsoy, Terrens N V Saaki, Michaela Wenzel, Simon Syvertsson, Taku Morimoto, Tjalling K Siersma, Leendert W Hamoen

“…Bacterial cytokinesis begins with polymerization of the tubulin homologue FtsZ into a ring-like structure at midcell, the Z-ring, which recruits the late cell division proteins that synthesize the division septum. Assembly of FtsZ is carefully regulated and supported by a dozen conserved cell division proteins. …”
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Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity by Yongxing Zhang, Junlei Xie, Ying Feng, Abdul Qadeer, Shanni Li, Xu Deng, Lipeng Zhu, Bo Kong, Zanxian Xia, Zanxian Xia

“…Throughout its prolonged interaction with the host, HSV-1 evades the innate immune system by encoding its own proteins. Post-translational modifications (PTMs) of these proteins play crucial roles in their function, activity, and interactions with other factors by modifying specific amino acids, thereby enabling a diverse range of protein functions. …”
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Functional study on the regulation of adventitious root formation by PpSAT4 gene in peach rootstock ‘GF 677’ by HAO Lanlan, WANG Hong, ZHANG Fan, ZHANG Xuebing, YANG Yang

“…[Results] (1) Peach PpSAT4 gene with a sequence of 864 bp was cloned, encoding a protein with a molecular weight of 30.49 kD and an isoelectric point of 6.70. …”
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Research Progress on Enzymatic Preparation and Functional Properties of Bioactive Peptides in Hairtail by Yuanyuan WU, Kewei ZHENG, Wenzhu LI, Cheng LI, Xiaojun YAN, Qingbao MA, Wei JIANG

“…Hairtail is a significant economic fish species in China, rich in protein and other nutrients, making it an excellent source of bioactive peptides. …”
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Effects of Cooking Treatment on the Changes of Polyphenol and Antioxidant Activity in Sorghum Rice and Its Exploration on the Flavor Enhancement Based on the Multi-omics Technique by Ke LIU, Lei XU, Changyuan WANG, Zhijiang LI, Jingzhi DENG

“…Results showed that the protein, total starch, and fat contents in SRC were significantly decreased (P<0.05) in comparison with those in SR. …”
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Development of a Cost-Effective Plasma Thawer: A Potential Game-Changer in Blood Transfusion Technology by Shamrez Shahid, Muhammad Danish Mujib Mujib, Ahmad Zahid Rao, Muhammad Abul Hasan, Saad Ahmed Qazi

“…The samples were clear of solid and gelatinous particles, indicating no protein denaturation or overheating. A buzzer signaled the completion of each cycle. …”
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Distribution, traditional utilization, processing, and health benefits associated with the consumption of morama bean [Tylosema escululetum (Burch.)]: a survey from selected distri... by John Gwamba, Samuel Imathiu, John Kinyuru, Arnold Onyango, Masa Veronica Motaung

“…Abstract Morama bean [Tylosema escululetum (Burch.)] is a nutrient-dense underutilized legume that can address protein-energy and micronutrient malnutrition in developing countries. …”
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Impact of Lonicera hypoglauca leaf inclusion on immune and antioxidant responses in geese by Zonghao Lv, Zhen Li, Zhizhong Zhang, Gao Li, Qinghua Chen, Qian Lin

“…However, 12% LHL substitution abnormally altered the serum levels of various biochemical parameters, such as total protein, total cholesterol, urea, triglyceride and low-density lipoprotein (p < 0.05). …”
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Is It Scaly Anteater or Bat A Real Origin of The 2019-Novel CoV: A Probable Hypothesis? by Salar Ali, Taib Hama-Soor, Muhammed Babakir-Mina, Salvatore Dimonte, Francesco Greco

“…The phylogenetic trees for animal coronaviruses with the novel coronavirus-2019 have been created using a number of available complete protein sequences of envelope (E), membrane (M), nucleocapsid (N) and spike (S) proteins. …”
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Creatine and pregnancy outcomes, a prospective cohort study in low-risk pregnant women: study protocol by Deborah L De Guingand, Stacey J Ellery, Miranda L Davies-Tuck, Hayley Dickinson

“…Secondary outcome measures include dietary protein intake over pregnancy and any associations with maternal creatine, pregnancy events and birth outcomes.Ethics and dissemination Ethical approval was granted in August 2015 from Monash Health (Ref: 14140B) and Monash University (Ref: 7785). …”
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Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway by Yifan Lai, Jiawei Qiu, Kuang Zheng, Xiang Li, Yinuo Lin, Zhengzheng Li, Haiqiu Sun

“…Mechanistically, we discovered that metformin activates AMP-activated protein kinase (AMPK) signaling in HEI-OC1 cells stimulated by TBHP, thereby triggering mitophagy. …”
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Correlation of the cycle threshold value of SARS-CoV-2 by RT-PCR with biomarker levels in the prognosis of patients hospitalized with COVID-19 by Shweta Singhal, Geetika Rana, Atul K. Singh, Shekhar Pal, Shweta Thaledi

“…Different biochemical parameters, such as C-reactive protein (CRP), serum ferritin, D-dimer, Interleukin-6 and serum procalcitonin, were assessed for severity. …”
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Design and assessment of lipase-CuO nanoparticle conjugates for enhanced antimicrobial efficacy against clinical pathogens by Eman M. Handak, Dina H. Amin, Mai M. Elhateir

“…Also, CuO nanoparticles appeared as distinct, well-dispersed spherical particles with average size of 71.035 nm using TEM, while conjugate appears as large protein molecules linked to the nanoparticles. Also, using techniques like energy dispersive X-ray (EDAX) the resultant conjugates formation was confirmed as the elemental analysis approved its formation. …”
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Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways by Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh

“…At concentrations of 25–50 μM, resveratrol increased autophagy as measured by microtubule-associated protein 1A/1B-light chain 3 (LC3)-II/LC3-I ratio and enhanced lysosomal activity as assessed by a lysosomal activity reporter system. …”
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Proximate, Mineral Contents and Physicochemical Properties of <i>Chrysophyllum Albidum</i> (African Star Apple) Kernel Flour and Oil by S.S. Audu, C.I. Beetseh, D.U. Edward-Ekpu, A.A. Ewuga

“…The results obtained from the Proximate Analysis shows the kernel has a moisture content of 10.06±0.08 %, Ash content of 2.72±007 %, Crude lipid of 13.31±008 %, Crude Protein of 7.92±0.00 %, Crude Fibre of 1.59±0.00 % and Carbohydrate of 65.41±0.05 %. …”
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