Role of Janus Kinase inhibitors in the management of pulmonary involvement due to Long COVID-19 disease: A case control study by Pawan Kumar Singh, Vinod Kumar Sharma, Lokesh Kumar Lalwani, Dhruva Chaudhry, Manjunath B. Govindagoudar, Chaudhari Pramod Sriram, Aman Ahuja

“…At the time of follow-up, the majority of cases had a significant reduction in C-reactive protein (CRP) and D-dimer; however, the change in CRP and D-dimer was similar in both groups. …”
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Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study by Arthur Clement, Lee S Nguyen, Anousone Daulasim, Magali Souibri

“…We aimed to confirm the accuracy of troponin, analysed as time-dependent variable, to predict mortality independently from other biomarkers; and to assess the incidence and prognosis of a 10 times upper normal value threshold (troponin10N) used in the current fourth definition of myocardial infarction.Methods In a prospective cohort of patients who underwent cardiopulmonary bypass cardiac procedures, we assessed the association between serum levels of troponin, creatinine, bilirubin, serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), C-reactive protein (CRP), lactate and in-hospital mortality. …”
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Extraction, GC-MS analysis, cytotoxic, anti-inflammatory and anticancer potential of Cannabis sativa female flower; in vitro, in vivo and in silico by Waqas Safir, Arif Malik, Arif Malik, Haleema Saadia, Ayesha Zahid, Jinyao Li

“…The bioinformatics analysis of molecular docking proved significant ligand-protein interactions of CBD, THC, and humulene with cancer-associated proteins such as PD-1/PD-L1, TNF-α, and MMP-9. …”
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The gastric microbiome altered by A4GNT deficiency in mice by Dawei Gong, Dawei Gong, Yuqiang Gao, Rui Shi, Xiaona Xu, Mengchao Yu, Shumin Zhang, Lili Wang, Quanjiang Dong

“…BackgroundSelective antimicrobial effects have been found for α1,4-linked N-acetylglucosamine residues at the terminus of O-glycans attached to a core protein of gastric gland mucin. A4gnt encodes α1,4-N-acetylglucosaminyl transferase, which is responsible for the biosynthesis of α1,4-linked N-acetylglucosamine. …”
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Genome assembly of Hawaiian flower thrips Thrips hawaiiensis (Thysanoptera: Thripidae) by Xiaodi Hu, Houjun Tian, Yixin Chen, Yueqin Zheng, Hui Wei, Jian-Ping Chen, Chuan-Xi Zhang, Yong Chen, Yiyuan Li

“…BUSCO analysis demonstrated the T. hawaiiensis genome assembly has a high-level completeness of 98.7%. In total, 18,289 protein-coding genes were annotated and 26.69% of the genome were annotated as repeats. …”
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Chemical composition of marandu palisade grass fertilized with nitrogen and potassium by K. C. Sales, J. G. Abreu, C. E. A. Cabral, A. Behling Neto, L. C. R. P. Silva, I. M. Silva Neto

“…The chemical characteristics evaluated were crude protein (CP), mineral matter (MM), neutral detergent fiber (NDF), acid detergent fiber (ADF), indigestible neutral detergent fiber (iNDF), total digestible nutrients (TDN) and net energy of lactation (NEF). …”
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Caenorhabditis elegans in the biological activity research of tea: From “little transparent” to “big star” by Lingwei Yang, Zhonghua Liu, Ligui Xiong, Yushun Gong

“…In C. elegans, active ingredients such as catechins and their derivatives, L-theanine, and caffeine have exhibited various biological effects, including slowing down aging, enhancing environmental adaptations, regulating protein homeostasis and glycolipid metabolism, and participating in immunomodulation. …”
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Maillard reaction products in plant-based dairy alternatives and their release during simulated gastrointestinal digestion by Kira Bieck, Franziska Ebert, Tilman Grune, Jana Raupbach

“…Total amounts of free and protein-bound glycation compounds ranged from 0.03 to 0.31 mg/100 g food for CML, 0.04–1.28 mg/100 g food for CEL and 0.69–2.84 mg/100 g food for MG-H1. …”
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Karakteristik Siswa, Daya Terima, dan Kesesuaian Standar Porsi dengan Angka Kecukupan Gizi pada Penyelenggaraan Makan Siang di SD Al Furqan Kabupaten Jember by Janiyah Intan Fitriani, Sulistiyani

“…Pada siswa perempuan energi, protein, lemak dan karbohidrat kategori tidak sesuai sebanyak 18 menu, 17 menu, 16 menu, 16 menu dan pada siswa laki-laki sebesar 14 menu, 13 menu, 16 menu, 17 menu.  …”
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Dramatic response of advanced pulmonary sarcomatoid carcinoma to tislelizumab combined with anlotinib: a case report by Ranran Li, Xiliang Di, Yuan Li, Hao Li, Chonghua Liu

“…Radiotherapy was performed for the brain and skull metastases, followed by treatment with tislelizumab combined with anlotinib, a programmed cell death protein 1 (PD-1) inhibitor with anti angiogenic drug, respectfully. …”
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Sealless Production Ultracentrifuge and Its Magnetically Self-Bearing Openable Motors for Purification in Viral Nanotechnology by Emanuel J. Hubmann, Daniel Steinert, Thomas Nussbaumer, Johann W. Kolar

“…The general working principle of the SL-PUCF system is experimentally validated by whey protein sedimentation. Furthermore, new future smart capability potential of the proposed new SL-PUCF technology suspended and driven by O-SBMs is unveiled as an outlook and examples shown in case studies.…”
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Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells by Wenshuai Li, Lirong Chen, Qi Zhou, Tiansheng Huang, Wanwei Zheng, Feifei Luo, Zhong Guang Luo, Jun Zhang, Jie Liu

“…The function of the target gene Hippocalcin-like protein 1 (HPCAL1) in HSCs was verified by Western blotting, qPCR, cellular immunofluorescence and co-IP in vivo and in vitro. …”
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Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes by Ravi Bhushan, Rimjhim Trivedi, Ritu Raj, Anjali Rani, Sangeeta Rai, Anima Tripathi, Shiv Govind Rawat, Ajay Kumar, Dinesh Kumar, Pawan K. Dubey

“…Metabolomic studies indicated significantly elevated gluconeogenesis in GDM, evidenced by decreased levels of alanine and increased levels of pyruvate and glucose compared to controls. siRNA-mediated knockdown of SNW1 in PANC1 cells resulted in significant down-regulation of alanine aminotransferase (ALT/GPT) and insulin receptor substrate (IRS1), while glucose transporters (GLUT2/GLUT4) and insulin (INS) were significantly up-regulated at both mRNA and protein levels. This study identified SNW1 as a novel insulin-resistant gene that induces hyperglycemia by elevating gluconeogenesis and decreasing glucose uptake. …”
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Protective and immunomodulatory effects of the novel probiotic yeast Pichia kudriavzevii isolated from a home-made kefir during infection in human colon epithelial cells: An explor... by Angela Maione, Marianna Imparato, Annalisa Buonanno, Marilena Galdiero, Elisabetta de Alteriis, Marco Guida, Emilia Galdiero

“…In particular, Y1 and CFS-Y-1 prevented damage to the intestinal epithelial function in LPS-induced Caco-2 cells by upregulating TJ protein expression and reducing ROS accumulation, as well as overproducing anti-inflammatory cytokines. …”
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Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

“…We found that dinaciclib-triggered apoptosis is triggered by CDK9 inhibition and the resultant reduction in RNA pol II phosphorylation, which leads to the downregulation of the oncogenic marker MYC, and the anti-apoptotic protein MCL-1. Specifically, we demonstrated that MCL-1 is a key apoptotic mediator for MB cells and co-treatment of dinaciclib with BH3 mimetics boosts the therapeutic efficacy of dinaciclib. …”
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The role of new hepatitis B vaccines in South Africa by G U van Zyl, T Maponga, H Rabie, J Taljaard

“…PreHevbrio, which includes three hepatitis B surface protein domains, instead of one, may also be more immunogenic, although clinical study data are still limited. …”
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Центральные и гормональные механизмы адаптации к десинхронизационному стрессу by Парвин Асад кызы Зульфугарова, Ариф Алиовсад оглы Мехтиев

“…В первой серии исследований изучалось влияние десинхронизации на уровень белка 2, опосредующего активность коллапсина (collapsin-response mediator protein 2 (CRMP2)) в гипоталамусе и эпифизе, методом твердофазного непрямого иммуноферментного анализа (НИФА). …”
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Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers by Andrey I. Egorov, William Xue, Jason Kobylanski, Miyu Fuzawa, Shannon M. Griffin, Timothy J. Wade, Michael Nye

“…Samples were tested for the neuroendocrine biomarkers alpha-amylase, cortisol, and dehydroepiandrosterone (DHEA) as well as immune system/inflammation biomarkers C-reactive protein (CRP), interleukin (IL)-1β, IL-6 and total immunoglobulin A (IgA). …”
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Diagnostic Accuracy of Next Generation Sequencing Panel using Circulating Tumor DNA in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis by Mariana M. Sebastião, Rodrigo S. Ho, João Paulo V. de Carvalho, Micha Nussbaum

“…The aim of the study was to carry out a systematic review and a meta-analysis in order to determine the accuracy of NGS of ctDNA to detect six oncogenic driver alterations: epidermal growth factor receptor (EGFR); anaplastic lymphoma kinase (ALK); ROS proto-oncogene 1, receptor tyrosine kinase (ROS-1); serine/threonine-protein kinase B-RAF (BRAF); RET proto-oncogene (RET); and MET proto-oncogene, receptor tyrosine kinase (MET) exon 14 in patients with aNSCLC. …”
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Complete chloroplast genomes of 13 species of the Impatiens genus for genomic features and phylogenetic relationships studies by Qinqin Yong, Meijun Li, Zhi Li, Chao Luo, Jinling Zhang, Xinxiang Bai

“…The results revealed that these chloroplast genomes all had double-stranded tetrad structures ranging in length from 151,284 bp to 152,421 bp, including a total of 113 genes, including 80 protein-coding genes, 29 transfer RNAs, and 4 ribosomal RNAs. …”
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