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901
Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?
Published 2025-02-01“…HIV infection augments angiogenesis via several mechanisms, most prominently, by the trans-activator of transcription (tat) protein mimicking VEGF-A by binding to its receptor, VEGFR-2, as well as upregulation of NRP-1, which enhances the interaction between VEGF-A and VEGFR-2. …”
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902
A systematic review on the influence of coagulopathy and immune activation on New Onset Atrial Fibrillation in patients with sepsis.
Published 2025-01-01“…There is evidence that C-reactive protein (CRP) is associated with NOAF, with hazard ratios 3.33 (3.32-3.35) p = 0.001 and odds ratios of 1.011 (1.008-1.014) p<0.001. …”
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903
Hyperparathyroidism in Patients with End-Stage Chronic Liver Disease (Clinical Observations)
Published 2024-12-01“…The liver plays an important role in mineral metabolism: metabolic activation of vitamin D, synthesis of vitamin D-binding protein and albumin, metabolism of parathyroid hormone, etc. …”
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904
Effect mechanism of H3PO4 on the formation and transformation of persistent free radicals in biochar
Published 2025-02-01“…The ingredients of biomass precursor, including cellulose, Fe, Ti, protein, etc., contributed to different effects on PFRs under H3PO4 modification. …”
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905
Decoding vascular aging: implications for atherosclerosis progression and clinical intervention
Published 2024-08-01“…In the review, we highlighted five altered vascular mechanisms in cardiovascular models: genomic instability, neurohormonal deregulation, epigenetics, protein regulation, and the gut microbiome. The articles were selected from various indexed scientific databases. …”
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906
Impact of morphological traits and irrigation levels on fresh herbage yield of sorghum x sudangrass hybrid: Modelling data mining techniques.
Published 2025-01-01“…Plant height of 251.22 cm, stem diameter of 7.03 mm, fresh herbage yield of 8010.69 kg da-1, crude protein ratio of 9.09%, acid detergent fiber 33.23%, neutral detergent fiber 57.44%, acid detergent lignin 7.43%, dry matter digestibility of 63.01%, dry matter intake 2.11%, and relative feed value of 103.02 were the descriptive statistical values that were computed. …”
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907
Exploring the characteristics of kombucha tea fermented with soursop (Annona muricata), Noni (Morinda citrifolia) and pineapple (Ananas comosus)
Published 2025-01-01“…There was also a significant difference (p<0.05) in proximate properties of infused and simple kombucha tea except for the crude protein content. The antioxidant analysis showed that addition fruit juices enhanced the antioxidant level of kombucha drinks. …”
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908
A study comparing energy consumption and environmental emissions in ostrich meat and egg production
Published 2025-02-01“…The energy consumption per 1000 units is 1,086,825.54 MJ for meat and 1,197,794.25 MJ for egg. When considering protein supply, egg production seems to be more justifiable in terms of energy efficiency compared to meat production. …”
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909
The Predictive Value of the Pentraxin 3 Concentration in Cumulus Cell Culture Media for the Embryo Implantation
Published 2022-08-01“… OBJECTIVE: Many studies on the interrelation of cumulus cells and oocytes, and research on cumulus protein factors continue. This study aims to investigate the relationship of Pentraxin 3 level with embryo implantation in the cumulus culture fluid. …”
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910
Rac1-dependent regulation of osteoclast and osteoblast differentiation by developmentally regulated GTP-binding 2
Published 2025-02-01“…Here, we investigated whether developmentally regulated GTP-binding protein 2 (Drg2), a subfamily of the GTPase superfamily, could affect bone mass by regulating osteoclast and osteoblast differentiation. …”
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911
Investigation of the physicochemical properties and pharmacokinetics of the active compounds in Quercus infectoria gall extract
Published 2024-12-01“…Ellagic acid, a polyphenol with antioxidant and anticancer properties, has complex pharmacokinetics due to conjugate formation and protein interactions. Gallic acid may impact its distribution, while phlorizin is being studied for its potential to inhibit glucosidase in diabetes management. …”
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912
Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD.
Published 2025-02-01“…The co-heritability of GERD and COPD was 39.7% (h2 = 0.397, SE = 0.074) and we identified several ancestry-independent loci associated with co-morbid GERD and COPD (within LINC02493 and FRYL) known to be involved in oxidative stress and G protein-coupled receptor (GPCR) signaling mechanisms. …”
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913
Spatio-temporal variation in pollen collected by honey bees (Apis mellifera) in rural-urban mosaic landscapes in Northern Europe.
Published 2025-01-01“…Pollen is a source of protein, lipids, vitamins and minerals for bees and other flower-visiting insects. …”
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914
Colonic growth factors (G-CSF, GM-CSF) and chemokines (MCP-1, MIP-1β) in severe ulcerative colitis
Published 2018-08-01“…Growth factor and chemokine levels in supernatant fluid after centrifugal separation of homogenate of 10 mg biopsy specimen were investigated by the protein analyzer «Bio-Plex» («Bio-Rad», USA). Biopsy specimens of uninvolved colonic mucosa resected in 10 cancer patients were used as a control. …”
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915
Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling.
Published 2025-01-01“…Calmodulin is a calcium binding protein that is essential in calcium signalling in the brain. …”
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916
Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing
Published 2025-02-01“…Additionally, we provide bulk RNA-seq datasets from two independent cohorts: 19 fresh frozen tissue samples (12 PMPs) and 34 formalin-fixed paraffin-embedded (FFPE) samples (25 PMPs). We also offer protein expression data from a tissue microarray (TMA) analysis of 90 samples (45 PMPs). …”
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917
Chronic exposure to diesel engine exhaust and alteration of the airway bacteriome
Published 2025-02-01“…Furthermore, the Spearman analysis indicated notable correlations of specific species with carbon content in airway macrophages (CCAM), club cell protein (CC16), FVC and FEV1. Taken together, our study provided new information on the difference in the airway bacterial signature under exposure to DEE and supported a potential new link between specific species and lung function in occupational populations.…”
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918
Differences in phenotypes of normal and malignant cells concerning chromosomal fragility and ganglioside expression
Published 2025-02-01“…Of particular interest were interactions involving gangliosides, the reduced form of tri-peptide glutathione (GSH) and/or of tumor-suppressor protein HACE1. The average titers of gangliosides and of anti-ganglioside antibodies in extracts from experimental in vitro models of laboratory-incubated cultures of mouse embryonic 3T3 fibroblasts, of mouse malignant myeloma cells, as well as of mixed cultures of both cellular types, were determined after previous passing of each one through GSH-agarose columns about the “selection” of the molecules in each one of the described samples, possessing affinity to GSH. …”
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919
Prognostic value of the lactate dehydrogenase to albumin ratio in advanced non-small cell lung cancer patients treated with the first-line PD-1 checkpoint inhibitors combined with...
Published 2025-02-01“…BackgroundThis study aimed to investigate the prognostic value of pretreatment lactate dehydrogenase to albumin ratio (LAR) in advanced non-small cell lung cancer (NSCLC) patients treated with first-line programmed cell death protein 1 (PD-1) checkpoint inhibitors and chemotherapy.MethodsA retrospective cohort study was conducted on advanced NSCLC patients treated with first-line PD-1 checkpoint inhibitors plus chemotherapy at Guangxi Medical University Cancer Hospital. …”
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920
Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications
Published 2025-02-01“…Cryo-electron microscopy and 2D classification of protein particles provided a projection structure identifying the oligomeric state of RlActR as a pentamer. …”
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