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821
Assessing the effects of partially substituting chicken breast meat with oyster mushroom stalk powder on the quality attributes of mushroom-chicken burgers
Published 2025-02-01“…A decrease in both crude protein and crude lipid was observed as the substitution level increased from 2.5 to 10%. …”
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822
Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Published 2025-02-01“…This study leverages protein engineering to enhance ACE2’s therapeutic potential for treating conditions such as respiratory viral infections, acute respiratory distress syndrome, and diabetes. …”
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823
The characteristics of intestinal microflora in infants with rotavirus enteritis, changes in microflora before and after treatment and their clinical values
Published 2025-02-01“…At the genus level, among the top 50 most abundant genera, 34 showed significant differences, with these differential genera correlating with certain clinical indicators such as dehydration levels and C-reactive protein (CRP). Notably, there were no significant differences in the microbiota before and after treatment in RV-infected children. …”
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824
Relationship between the ultrasound features of different molecular subtypes of breast cancer and positive PD-1/PD-L1 expression
Published 2025-02-01“…Objectives To analyze differences in programmed cell death protein 1/ligand 1 (PD-1/PD-L1) expression, as well as the relationships between ultrasound/contrast-enhanced ultrasound characteristics and PD-1/PD-L1 expression, among invasive breast cancer molecular subtypes. …”
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825
Drop-on-demand printing of amine-responsive fluorescence-ratiometric sensor array for online monitoring meat freshness
Published 2025-01-01“…Aiming to enable online freshness-monitoring of meat within modified-atmosphere package, we developed a ratiometric array that was fluorescently responsive to volatile organic compounds-ammonia (NH3) released by protein decaying. The array was consisted of two 3 mm × 6 mm rectangles precisely and uniformly printed with fluorescein isothiocyanate (FITC) as indicator and rhodamine B (RhB) as internal reference on the filter-paper, respectively. …”
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826
Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study
Published 2024-12-01“…Results: Bioinformatics analysis predicted that catechin inhibits three pro-inflammatory proteins: COX-2, HSP90, and IL-2. Catechin’s inhibitory potential was indicated by negative binding energies and interactions with amino acid residues critical for target protein activity. …”
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827
Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy
Published 2025-02-01“…Using human urine, model organisms, mass spectrometry, gene expression analysis, and the phage phenotype prediction model BACPHLIP, the results corroborated our hypotheses at the functional protein and gene levels. From a human health perspective, these data suggest that temperate phages may facilitate bacterial infections rather than function as protective agents. …”
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828
Vitamin D as a predictor of negative outcomes in hospitalized COVID-19 patients: An observational study
Published 2023-08-01“…Patients with low serum vitamin D levels have higher C-reactive protein levels 26.14 mg/L \[Q1, Q3: 16.61, 57.79\] compared to another group 13.43 mg/L \[Q1, Q3: 8.84, 27.58\]. …”
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829
Seed endophytes of malting barley from different locations are shaped differently and are associated with malt quality traits
Published 2025-02-01“…Association analysis showed a significant negative correlation between bacterial alpha diversity indices (Faith PD and Shannon indices) and malt quality traits for barley protein (BP), free amino nitrogen (FAN), diastatic power (DP) and alpha amylase (AA), while fungal alpha diversity (Shannon and Simpson) showed significant negative relationship with β-D-glucan content. …”
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830
Symbiotic nutrient cycling enables the long-term survival of Aiptasia in the absence of heterotrophic food sources
Published 2023-05-01“…This shrinking was accompanied by a reduction in host protein content and algal density, indicative of severe nitrogen limitation. …”
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831
Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases
Published 2025-05-01“…In rubella virus–infected cells, we discover macrophage-specific evolution of the rubella virus E1 capsid protein. Finally, we interrogate skin biopsies from many established nonvirally mediated inflammatory skin diseases and do not find consistent evidence of viral infection in any condition. …”
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832
The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes
Published 2025-02-01“…The field of cancer research is increasingly focusing on the role of tumor-related oncogenes and heterogeneous proteins in the development of cancer. Studies indicate that there is a close connection between solid tumors and epithelial splicing regulatory protein 1 (ESRP1). …”
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833
The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis.
Published 2025-01-01“…Cul3 engages dozens of adaptor proteins to recruit hundreds of substrates for ubiquitination, but the adaptors that impact sleep and synapses remain ill-defined. …”
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834
Using HBmito Crimson to Observe Mitochondrial Cristae Through STED Microscopy
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835
Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts
Published 2025-02-01“…We developed a dual-fluorescent protein reporter mouse to prospectively study the post-transcriptional-level transition from membrane anchored to secretory immunoglobulin M; μM-PAS and μS-PAS, respectively. …”
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836
Development and characterization of a double-crested cormorant hepatic cell line, DCH22, for chemical screening
Published 2025-02-01“…The phase II metabolism gene, UGT1A1, was upregulated following HBCD exposure and DCH22 spheroids expressed vitellogenin protein after exposure to 17α-ethinylestradiol. Based on these data, the novel DCH22 cell line, cultured as 3D spheroids, has potential use as an alternative to DCEH for chemical screening and will permit the evaluation of avian species differences in sensitivity from an in vitro screening perspective.…”
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837
Comparing the effect of Centella asiatica L. and Acalypha indica L. treatment to carbonyl and glutathione level in the brains of old rats
Published 2022-06-01“…Conclusion: Centella asiatica can reduce the protein destruction that occurs with increasing age. …”
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838
Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates
Published 2024-09-01“…Cysteine (Cys), one of the less abundant AAs in many biological proteins, plays a vital role in the catalysis, signal transduction, and redox regulation of gene expression. …”
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839
Association between dietary components and gut microbiota: a Mendelian randomization study
Published 2025-01-01“…Objective: To explore the causal association between dietary components (carbohydrate, fat, protein, and sugar) and 119 genera of known gut microbiota using Mendelian randomization (MR) methods. …”
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840
A paradoxical population structure of var DBLα types in Africa.
Published 2025-02-01“…The var multigene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), central to host-parasite interactions. …”
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