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781
Plectin, a novel regulator in migration, invasion and adhesion of ovarian cancer
Published 2025-02-01“…Plectin (PLEC), a 500 kDa scaffolding protein, has gained prominence in recent years due to its pivotal role in various cellular biological functions such as cell morphology, migration and adhesion, while the accurate role of PLEC in OC remains elusive. …”
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782
Prediction of hemolytic peptides and their hemolytic concentration
Published 2025-02-01“…Among classification models, including machine learning (ML), quantum ML, and protein language models, a hybrid model combining random forest (RF) and a motif-based approach achieves the highest area under the receiver operating characteristic curve (AUROC) of 0.921. …”
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783
Expanding Yarrowia lipolytica’s metabolic potential for detoxification of cyanogenic glycosides in edible plants
Published 2025-02-01“…It upregulated ribosome biogenesis, the sec-dependent protein export pathway, and the sulfur relay system to facilitate the production and transmembrane efflux of the secreted GH1 hydrolase. …”
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784
RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons
Published 2025-02-01“…In mitotic spindle formation, HAUS is antagonized by the microtubule bundling protein NUMA1. Numa1 mRNA is a MOV10 CLIP target and is among the genes significantly decreased in Mov10 Deletion hippocampus. …”
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785
UJI BEBERAPA JENIS PUPUK ORGANIK TERHADAP TANAMAN CAISIM(Brassica campestris L)
Published 2015-02-01“… ABSTRAK Caisim merupakan komoditi tanaman sayuran yang dibutuhkan sebagai sumber protein dan vitamin bagi manusia, dan akhir-akhir ini semakin meningkat pula permintaan pasarnya. …”
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786
Comparing the Urine Ketone Strip Test and the Handheld Ketone Meter to Diagnose Ketosis in Early Lactation Dairy Cows
Published 2012-10-01“…Clinical and subclinical ketosis (SCK) can cause reduced milk yield, decreased milk protein, reduced reproductive capacity, and increased risk of displaced abomasum. …”
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787
Real-time analysis of initiation regulation systems during the progression of the reconstituted chromosomal replication cycle
Published 2025-02-01“…Abstract Chromosome replication in Escherichia coli is primarily regulated at the initiation stage, where the DnaA protein activates replication at the chromosomal origin, oriC. …”
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788
Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies
Published 2024-10-01“…Vaccines like BNT162b2 and mRNA-1273 target the receptor-binding domain (RBD) of the spike (S) protein, prompting B cells to produce neutralizing antibodies that block the RBD from binding to the Angiotensin-Converting Enzyme 2 (ACE2) receptor, preventing infection. …”
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789
Cryo-electron tomography pipeline for plasma membranes
Published 2025-01-01“…Abstract Cryo-electron tomography (cryoET) provides sub-nanometer protein structure within the dense cellular environment. …”
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790
Real-time IncuCyte® Assay for the Dynamic Assessment of Live and Dead Cells in 2D Cultures
Published 2025-02-01“…Cell viability and cytotoxicity assays are commonly used to investigate protein function and to evaluate drug efficacy in cancer and other disease models. …”
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791
Thrombotic Complications in Inflammatory Bowel Disease
Published 2019-05-01“…The concentration of fibrinogen — a protein of the acute inflammation phase — increases significantly. …”
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792
Specialized contact sites regulate the fusion of chlamydial inclusion membranes
Published 2024-10-01“…Ultimately, these inclusions fuse together in a process that requires the chlamydial protein IncA. Here, we show that inclusions form unique contact sites (inclusion contact sites, ICSs) prior to fusion, that serve as fusogenic platforms in which specific lipids and chlamydial proteins concentrate. …”
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793
Effects of hyaluronic acid on bone graft healing: An experimental study on sheep
Published 2019-12-01“…So many interpositional graft materials like hyaluronic acid and bone morphogenetic protein have been introduced to such material to induce osteoinductivity of graft material. …”
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794
Comparing the Urine Ketone Strip Test and the Handheld Ketone Meter to Diagnose Ketosis in Early Lactation Dairy Cows
Published 2012-10-01“…Clinical and subclinical ketosis (SCK) can cause reduced milk yield, decreased milk protein, reduced reproductive capacity, and increased risk of displaced abomasum. …”
Get full text
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795
Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast.
Published 2006-03-01“…We also found 39 genes that have an important role in telomere maintenance or cell proliferation in the absence of telomerase, including genes that participate in deoxyribonucleotide biosynthesis, sister chromatid cohesion, and vacuolar protein sorting. Given the large number of loci identified, we investigated telomere lengths in 13 wild yeast strains and found substantial natural variation in telomere length among the isolates. …”
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796
Noninvasive markers of inflammatory bowel disease activity
Published 2018-08-01“…Blood serum cytokines: IL-4, IL-8, tumor necrosis factor α (TNF-α) and fecal calcium binding protein (calprotectin) were assessed. Results. Fecal calprotectin and TNF-α levels were much higher in patients with high disease activity and extent of inflammatory process. …”
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797
Impact of the crosstalk between the PTEN and PAFR as well as PAFR and EGFR pathways in cancer
Published 2025-01-01“…Importantly, high tumor expression of a G-protein coupled platelet-activating factor-receptor (PAFR) is associated with increased tumor progression as well as decreased overall survival and poor prognosis in malignancies such as non-small cell lung cancer (NSCLC). …”
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798
Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury
Published 2025-02-01“…Corresponding targeted medications such as Abatacept, chemokine receptor (CCR) inhibitors, CDDO-Im (2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide), adenosine monophosphate-activated protein kinase (AMPK) activators, and Adalimumab are currently under investigation. …”
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799
Microscopic origin of the spatial and temporal precision in biological systems
Published 2025-03-01“…In cell lysis, it is shown that precise timing is due to the coupling of holin protein accumulation and the breakage of the cellular membrane. …”
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800
How energy determines spatial localisation and copy number of molecules in neurons
Published 2025-02-01“…Abstract In neurons, the quantities of mRNAs and proteins are traditionally assumed to be determined by functional, electrical or genetic factors. …”
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