MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy by Jiabin Liang, Jingxiu Zhao, Lin Yang, Qian Wang, Jing Liao, Jianhao Li, Weizhao Zhuang, Fanghong Li, Jinxian He, Yukuan Tang, Hanwei Chen, Chen Huang

“…Methods The in vitro studies included the effects of DSS duration on MSCs, and the characterization of DSS-Exo and Exo, followed by the assessment of RNA and protein expression levels of peritoneal fibrosis markers and inflammatory cytokines levels after treating human peritoneal mesothelial (HMrSV5) cells. …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“…Hyper ammonia- producing bacteria (HAB) are responsible for a faster rate of ammonia production from dietary protein degradation, resulting in wastage of feed protein and environmental pollution. 16S rRNA sequences of enrichment culture of buffalo rumen content revealed Proteo-bacteria (61.1 - 68.2%) as most predominant bacteria followed by Unclassified bacteria (24-29%), Firmicutes (2.8-6.9%), Bacteriodetes (0.9-2%), Actinobacteria (0.1-1.1%), Fusobacteria (0.04-0.7%) and Synergistetes (0.1-0.4%) at phylum level. …”
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Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice by Kuanhang Li, Zhengzheng Zhou, Yi Cao

“…However, lysosomal-associated membrane protein 2 (Lamp2) showed different trend, that it was significantly increased in intestines but decreased in livers. …”
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Effectiveness of Contrast Agents and Molecular Indicators in Alzheimer's Diagnosis Through PET and SPECT Imaging on Animal Models by Yasaman Abaszadeh, Ramin Ardalani, Athena Dehghan Najm Abadi

“…Respectively, Amyloid beta, Tau protein, Translocator protein (TSPO), Acetylcholinesterase (AChE), Monoamine oxidase B (MAO-B), and Gonadotropin-releasing hormone receptor (GnRHR) were identified the most as biomarkers in studies. …”
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Effect of supplementation of phytoadditive mixtures on live weight, blood indices, hormonal profile and reproductive performance in Black Bengal goats by Amit Kumar Singh, Champak Bhakat, Upali Kisku, Muthupalani Karunakaran, Tapas Kumar Dutta

“…Blood parameters including glucose, urea, total protein, albumin, globulin, ALT, AST, ALP, WBC, RBC, Hb and PCV% were similar (P > 0.05) in all groups. …”
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RETRACTED ARTICLE: Combined treatment of glibenclamide and CoCl2 decreases MMP9 expression and inhibits growth in highly metastatic breast cancer by Zhe Rong, Li Li, Fei Fei, Lailong Luo, Yang Qu

“…Abstract Background To observe the influence of combination treatment with glibenclamide and CoCl2 on the growth and invasiveness of TA2 breast cancer, and to detect the protein and mRNA expression of MMP9. Methods 50 adult female TA2 mice were randomly divided into 5 groups including DMSO control, CoCl2, glibenclamide, CoCl2 + glibenclamide and paclitaxel. …”
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Two sexually compatible monokaryons from a heterokaryotic Lentinula edodes strain respond differently to heat stress by Yuan Guo, Wenyu Jiao, Yajie Zhang, Meiting Tan, Qi Gao, Yu Liu, Shouxian Wang

“…For SP3, the differentially expressed genes (DEGs) were significantly enriched in Mitogen-Activated Protein Kinase (MAPK) signaling, cell cycle and sugar metabolism, whereas those DEGs for SP30 were enriched in glyoxylate and dicarboxylate metabolism, and protein processing. …”
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Investigation of antioxidant, antidiabetic, and antiglycation properties of Sonchus oleraceus and Lobularia maritima (L.) Desv. extracts from Taza, Morocco by Abdelmounaim Laabar, Imad Kabach, Sara El Asri, Amr Kchikich, Soufiane Drioua, Ayoub El Hamri, Moulay El Abbes Faouzi

“…Antioxidant activity was evaluated through DPPH, FRAP, ABTS, and metal-chelating assays, while flavonoid and polyphenol content was quantified spectrophotometrically.Antidiabetic potential was assessed via inhibition of α-glucosidase and α-amylase, and antiglycation activity was analyzed by measuring protein thiol preservation and fructosamine levels. …”
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Grape stems as sources of tryptophan and selenium: Functional properties and antioxidant potential by Raquel Fernandes, Concepción Medrano-Padial, Rui Dias-Costa, Raúl Domínguez-Perles, Cláudia Botelho, Rúben Fernandes, Ana Novo Barros

“…Tryptophan, selenium, and phenolic compounds, which regulate cognitive functions, protein and enzyme synthesis, and antioxidant processes, were analysed. …”
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CD163, a novel receptor for TNF, was revealed in situ by proximity ligation assay by Alexandre Cousin, Myriam Oger, Aymar de Jenlis, Audrey Lejart, Laure Barbier, Diane Riccobono, Xavier Holy, Anne-Laure Favier, Krisztina Nikovics

“…Our study compared co-localization using the Proximity Ligation Assay (PLA), a recently developed in situ protein-protein interaction technique. In an inflamed porcine lung model, we demonstrated the efficacy of PLA in detecting interactions between tumor necrosis factor (TNF) and its receptors TNFR1 and TNFR2. …”
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Molecular characterization and potential therapeutic roles of miR125a in HER-2 positive gastric cancer by Afraa Mamoori, Zena Hasan Sahib, Haider Alkafaji

“…Immunohistochemical study was used to measure the expression of HER2 protein in these carcinomas. In addition, the level of expression of this miRNA is correlated to different pathological and clinical parameters. …”
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The optimization of calcareous soil cation exchange capacity via the feather hydrolysate and N-P fertilizers integration by Doaa A. Goda, Eman H. El-Gamal, Mohamed Rashad, Yasser R. Abdel-Fattah

“…The results revealed that the protein concentration in the customized conditions was 1173.53 µg ml−1. …”
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Exploration of techno-functional properties and metabolomic profile of Scleroderma texense (Phutuki Mushroom): a comparative study with Agaricus bisporus (white button mushroom) by Arun Kumar Gupta, Avinash Kumar Jha, Bindu Naik, Vijay Kumar, Sarvesh Rustagi, Milad Tavassoli

“…Results obtained from FTIR revealed the presence of functional groups associated with fat (1740 cm−1), protein (1560 cm−1), polysaccharides (1500–750 cm−1), and moisture (3300 cm−1) in mushroom samples. …”
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Capivasertib enhances chimeric antigen receptor T cell activity in preclinical models of B cell lymphoma by Hui-Ju Hsieh, Ryan Urak, Mary C. Clark, Larry W. Kwak, Stephen J. Forman, Xiuli Wang

“…Phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling is involved in the growth of normal and cancer cells and is crucial for T cell activation. …”
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The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion by Jing Yang, Zhunan Li, Aicong Li, Yayi Liu, Xinyan Zhang, Yong Zhang, Yuanpeng Gao

“…Coronin-1A is a host cytoskeleton-associated protein that is crucial for understanding the inhibition of phagosome-lysosome fusion by Mycobacterium tuberculosis (M.tb) to evade host innate immune clearance. …”
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Effect of feeding rate and composition for bioconversion of wastewater treatment plant sludge from the milk and creamer processing industries using black soldier fly larvae by Ursada Riang, Bagastyo Arseto Yekti, Purnomo Alfan

“…Black Soldier Fly Larvae (BSFL) have degraded various organic materials, transforming nutritious organic waste into high-quality protein biomass. BSFL potentially converts sludge when mixed with other nutrient sources like food waste. …”
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Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…FI-associated genes were identified through expression quantitative trait loci (eQTL) analysis, with enrichment analysis and a protein-protein interaction (PPI) network used to explore potential pathways and core genes.Results: Forward MR analysis revealed a significant causal relationship between elevated FI levels and AGA (P=0.027, OR=43.944). …”
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The potential of local orange peel-derived eco-enzymes in producing indole acetic acid by Siska Alicia Farma, Nurfa Dewiza Luzik, Salma Sakina, Irma Leilani Eka Putri, Linda Advinda, Azwir Anhar

“…The presence and concentration of IAA were determined using spectrophotometry at a wavelength of 530 nm, while total protein levels were measured using the Warburg-Christian method. …”
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Pemanfaatan Pelayanan Posyandu sebagai Faktor Risiko Dominan Kejadian Gagal Tumbuh pada Balita di Wilayah Puskesmas Pringsurat by Diah Aprilia Putri, Suyatno Suyatno, Siti Fatimah

“…Faktor lainnya, seperti pola asuh, infeksi, berat lahir, jenis kelamin, dan konsumsi protein, tidak menunjukkan signifikansi. Kesimpulan: Kurangnya pemanfaatan posyandu merupakan faktor dominan penyebab gagal tumbuh pada balita di wilayah Puskesmas Pringsurat.…”
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The use of calcined oyster shell and rock flour to improve the nutritive value of rice straw preserved in airtight wrapping for feeding cattle under a tethered herding system by Khalil Khalil, Ananta Dwi, Andri Andri, Hermon Hermon

“…Parameters measured included DM intake, weight gain, blood hematology, protein, and mineral profiles. Results found that preserved rice straws had higher moisture and crude protein content than fresh straws. …”
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