Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators by S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema, Craig N. Jenne

“…Our primary objective was to determine levels of seven inflammatory protein mediators previously associated with intra-abdominal inflammation (C-reactive protein—CRP, procalcitonin—PCT, interleukin-6 (IL), IL-8, IL-10, monocyte chemoattractant protein-1—MCP-1, and serum amyloid A—SAA) in a cohort of children with suspected appendicitis. …”
Get full text

Leucine-Rich Repeat Protein Family Regulates Stress Tolerance and Development in Plants by Hao Zhiqi, Wang Tingyi, Chen Dongdong, Shen Lan, Zhang Guangheng, Qian Qian, Zhu Li

“…LRR proteins can be divided into two categories: those containing LRR domains along with other structural elements, which are further subdivided into five groups, LRR receptor-like kinases, LRR receptor-like proteins, nucleotide-binding site LRR proteins, LRR-extensin proteins, and polygalacturonase-inhibiting proteins, and those containing only LRR domains. …”
Get full text

Metal-free production of natural blue colorants through anthocyanin–protein interactions by Wenxin Wang, Peiqing Yang, Fuqing Gao, Yongtao Wang, Zhenzhen Xu, Xiaojun Liao

Subjects: Get full text

Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…We recently discovered that cold-inducible RNA-binding protein released into the extracellular space acts as a DAMP. …”
Get full text

FAM98 Family Proteins Play Distinct Roles in Osteoclastogenesis and Bone Resorption by Lei Wang, Tarun Minocha, Bhaba K. Das, Mikaela D. Kunika, Aarthi Kannan, Ling Gao, Subburaman Mohan, Weirong Xing, Kottayil I. Varughese, Haibo Zhao

“…There are three FAM98 family proteins (FAM98A/B/C) in humans and mice. Their physiological functions remain largely unknown. …”
Get full text

Prognostic Value of Melanoma Inhibitory Activity Protein in Localized Cutaneous Malignant Melanoma by Angela Sandru, Eugenia Panaitescu, Silviu Voinea, Madalina Bolovan, Adina Stanciu, Sabin Cinca, Alexandru Blidaru

“…To identify if melanoma inhibitory activity (MIA) protein could represent a tool for selecting high risk early stages melanoma patients. …”
Get full text

Severe deviation in protein fold prediction by advanced AI: a case study by Jacinto López-Sagaseta, Alejandro Urdiciain

“…Abstract Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino acid sequences. …”
Get full text

Adaptability of high-protein barley genotypes under the conditions of the Volga-Vyatka region by I. Yu. Zaytseva, I. N. Shchennikova, L. V. Panikhina, E. V. Dyagileva

“…One of the urgent tasks is to develop high-yielding cultivars with good grain quality, thus reducing protein deficiency in farm animal feeds and meeting the need for fodder grain that increases every year. …”
Get full text

Detection of antibodies to non-structural proteins of foot-and-mouth disease virus (review) by A. S. Yakovleva, A. V. Scherbakov

Subjects: Get full text

Procalcitonin and C-reactive protein - early predictors of low colorectal anastomotic leakage by Yu. A. Shelygin, M. A. Tarasov, M. A. Sukhina, I. V. Zarodnyuk, Ye. G. Rybakov

“…To determine diagnostic value of procalcitonin (PCT) and C-reactive protein (CRP) at anastomotic leakage (AL) following lower anterior resection (LAR) of the rectum. …”
Get full text

Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…FA DD is a key adaptor protein for the formation of the C D95 DISC and activation of caspase-8 in the receptor complex. …”
Get full text

Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…Glucose-sensing ChREBP and MondoA are transcriptional factors involved in the lipogenic, inflammatory, and insulin signaling pathways implicated in metabolic disorders; however, limited ocular studies have been conducted on these proteins. We aimed to investigate the potential role of ChREBP in the pathogenesis of diabetic retinopathy (DR). …”
Get full text

Toxic Effect of Cadmium on the Electrophoretic Protein Patterns of Gill and Muscle of Oreochromis mossambicus by K. Muthukumaravel, P. Kumarasamy, A. Amsath, M. Gabriel Paulraj

“…The present study was carried out to determine the sub lethal toxic effects of the heavy metal cadmium on the electrophoretic protein fractions of gill and muscle tissues of Oreochromis mossambicus. …”
Get full text

Investigation of Characteristics Whey Protein Isolate/Chitosan with Silica Addition in Biocomposite Film by Ika Zuwanna, Medyan Riza, Sri Aprilia, Yanna Syamsuddin, Syahiddin Said, Rozanna Dewi

Subjects: Get full text

Toward consumer-focused food policies: a toolbox for encouraging the protein transition by Hans Dagevos, Marleen C. Onwezen

Subjects: Get full text

Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target? by Iris Cadima-Couto, Joao Goncalves

“…APOBEC proteins appeared in the cellular battle against HIV-1 as part of intrinsic cellular immunity. …”
Get full text

Systemic Proteomic Analysis Reveals Distinct Exosomal Protein Profiles in Rheumatoid Arthritis by Qiu Qin, Ronghua Song, Peng Du, Chaoqun Gao, Qiuming Yao, Jin-an Zhang

“…A total of 278 exosomal proteins were detected. Among them, 32 proteins were significantly upregulated (FC≥2.0 and P<0.05) and 5 proteins were downregulated (FC≤0.5 and P<0.05). …”
Get full text

Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves by A. A. Anashkina, E. N. Kuznetsov, A. V.  Batianovskii, L. A. Uroshlev, V. G. Tumanyan, N. G. Esipova

Subjects: “…protein­dna complexes…”
Get full text

Global Alignment of Pairwise Protein Interaction Networks for Maximal Common Conserved Patterns by Wenhong Tian, Nagiza F. Samatova

“…A number of tools for the alignment of protein-protein interaction (PPI) networks have laid the foundation for PPI network analysis. …”
Get full text

Livedoid vasculopathy with mononeuritis multiplex associated with protein S deficiency mimicking systemic vasculitis by Vikramraj K Jain, Krishnamurthy Hegde, Renuka Panchagnula

Subjects: Get full text