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  1. 18961
  2. 18962

    Evidence-based exercise recommendations to improve functional mobility in older adults - A study protocol for living systematic review and meta-analysis [version 2; peer review: 2... by Claudia Volecker-Rehage, Uros Marusic, Bettina Wollesen, Antoine Langeard, Tamar Yellon, Anna Wunderlich, Vera Belkin, Guoping Qian, Eleftheria Giannouli, Zbigniew Ossowski, Rafael A. Bernades, Yael Netz, Rajesh Sighdel

    Published 2025-01-01
    “…The main research questions are: Which exercise types are most beneficial for improving functional mobility in various populations of older adults? Which physical exercise characteristics in terms of frequency, intensity, time and duration will achieve the greatest benefit in terms of the defined outcomes, i.e, the functional mobility of older adults? …”
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    Article
  3. 18963

    Advances in Cell and Immune Therapies for Melanoma by Tanase Timis, Sanda Buruiana, Delia Dima, Madalina Nistor, Ximena Maria Muresan, Diana Cenariu, Adrian-Bogdan Tigu, Ciprian Tomuleasa

    Published 2025-01-01
    “…The incidence rate of cutaneous melanoma is on the rise worldwide, due to increased exposure to UV radiation, aging populations, and exposure to teratogen agents. However, diagnosis is more precise, and the increased number of new cases is related to the improved diagnosis tools. …”
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    Article
  4. 18964

    Surveillance of tick-borne encephalitis virus foci in Slovakia: A seroprevalence study in ruminants combined with virus detection in ticks by Martina Ličková, Bronislava Víchová, Markéta Derdáková, Monika Sláviková, Sabína Fumačová Havlíková, Dana Zubriková, Diana Selyemová, Michal Chvostáč, Lucia Blaňarová, Viktória Čabanová, Veronika Vaňová, Lucia Šulejová, Jana Kerlik, Tomáš Szemes, Katarína Šoltys, Boris Klempa

    Published 2025-01-01
    “…The seroprevalence of TBEV in farm animals is an effective tool for identifying areas of virus circulation and guiding more in-depth field investigations of local tick populations. This combined approach of serological and virological surveillance provides valuable data for assessing the risk of alimentary TBEV infections and characterizing local TBEV strains.…”
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  5. 18965

    Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

    Published 2024-11-01
    “…Factors positively linked to total numbers of ARGs included human and livestock populations; whereas mean annual precipitation was negatively linked to resistance gene quantities. …”
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  6. 18966
  7. 18967

    Real-world enrollment for a prospective clinico-genomic database using a pragmatic technology-enabled platform by Alexia Exarchos, Ariel B. Bourla, Maneet Kaur, Katja Schulze, Sophia Maund, Yi Cao, Yihua Zhao, Elizabeth H. Williams, Sarah C. Gaffey, Richard Zuniga, Shaily Lakhanpal, Vladan Antic, Michelle Doral, Johanna Sy, Neal J. Meropol, Anne C. Chiang

    Published 2025-04-01
    “…Enrollment rates were estimated from eligible populations at individual centers. Clinical data from routinely collected EHR documentation were centrally processed and normalized for quality control. …”
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    Article
  8. 18968

    Trends in incidence, mortality, and DALYs of cystic echinococcosis in Central Asia from 1992 to 2021: an age-period-cohort analysis by Wulan Talafuhan, Kaibinuer Tuoheti, Ye Lixia, Qi Shuang, Mieyier Yeerjiang, Guzalinuer Aizezi, Wei Jingjing, Peierdun Mijiti, Peierdun Mijiti

    Published 2025-01-01
    “…The highest incidence rates were among middle-aged and older adult populations. Although mortality and DALY rates decreased across all age groups, the decline was less than the global trend. …”
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  9. 18969
  10. 18970

    Nicotinic α7 receptors on cholinergic neurons in the striatum mediate cocaine-reinforcement, but not food reward by Michael Fritz, Michael Fritz, Michael Fritz, Priscila Batista Rosa, Daniel Wilhelms, Daniel Wilhelms, Maarit Jaarola, Johan Ruud, David Engblom, Anna M. Klawonn, Anna M. Klawonn, Anna M. Klawonn, Anna M. Klawonn

    Published 2025-01-01
    “…However, the role of specific cholinergic receptor subtypes on different neuronal populations remain elusive. Here, we studied the function of nicotinic acetylcholinergic alpha 7 receptors (α7 nAChRs) in cocaine and food-enforced behaviors. …”
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  11. 18971

    Biological subphenotypes in patients hospitalized with suspected infection in Thailand: a secondary analysis of a prospective observational studyResearch in context by Prapassorn Poolchanuan, Taylor D. Coston, Viriya Hantrakun, Parinya Chamnan, Gumphol Wongsuvan, Pavan K. Bhatraju, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West, Shelton W. Wright

    Published 2025-02-01
    “…Summary: Background: Subphenotypes of infected patients have been reported in Europe and North America, but few studies have investigated populations in Southeast Asia. We sought to identify and differentiate subphenotypes of patients hospitalized with suspected infection in rural Thailand using biological markers implicated in the dysregulated host response. …”
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  12. 18972

    Dissecting the role of single nucleotide polymorphism of lymphotoxin beta gene during pig domestication using bioinformatic and experimental approaches by R. B. Aitnazarov, E. V. Ignatieva, N. E. Bazarova, V. G. Levitsky, S. P. Knyazev, Y. Gon, N. S. Yudin

    Published 2016-01-01
    “…The low responsiveness of the immune system could become hereditary through fixation of genes with “unfavorable” mutations in populations. The objectives of this work are: 1) determination of frequencies of genotypes and alleles of the rs340283541 SNP in the gene for the lymphotoxin beta (LTB) cytokine in pigs of domestic breeds and wild boars; 2) investigation of the expression of LTB mRNA in minipigs with different genotypes, and 3) bioinformational analysis of the putative functional role of the SNP. …”
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  13. 18973
  14. 18974
  15. 18975

    Global, regional, and national burden of very early-onset colorectal cancer and its risk factors from 1990 to 2019: A systematic analysis for the global burden of disease study 201... by Zhen Junhai, Meng Yang, Tan Zongbiao, Yan Wenxuan, Li Tiange, Wu Yanrui, Liu Chuan, Dong Weiguo

    Published 2025-02-01
    “…Conclusions: The increase in CRC burden among populations younger than 35 years globally requires vigilance from policy makers, physicians, and young individuals themselves, especially those regions experiencing faster growth burden of very EOCRC.…”
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    Article
  16. 18976

    Current Status, Challenges, and Perspectives in the Conservation of Native Honeybees and Beekeeping in Cambodia by Eric Guerin, Chhouk Chheang, Chainarong Sinpoo, Korrawat Attasopa, Nuttapol Noirungsee, Huoqing Zheng, Tial C. Ling, Patcharin Phokasem, Terd Disayathanoowat

    Published 2025-01-01
    “…Although native bees are not at immediate risk of extinction, their crucial ecological and socio-economic roles, coupled with the threats to their populations, necessitate the urgent implementation of conservation policies. …”
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    Article
  17. 18977

    Comparison between sevoflurane and propofol induction in I-gel insertion in pediatric patients undergoing inguinal herniotomy by Harshita Singh, Harpreet Kaur, Shirin Parveen, Narendra Singh Bafila, Kirtika Yadav, Anam Rizwan, Dhruvraj Singh

    Published 2025-02-01
    “…Future research could explore the long-term outcomes and broader applications of these findings in diverse pediatric populations.…”
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    Article
  18. 18978

    Land-use and land-cover changes and emerging non-tuberculous and tuberculous infectious diseases in humans and animals: a mixed-methods review of research findings from global and... by Jean-François Guégan, Carlos A Vargas Campos, Christine Chevillon, Ahmadou Sylla, Magdalene Dogbe, Kayla M Fast, Jennifer Pechal, Alex Rakestraw, Matthew E Scott, Michael W Sandel, Heather Jordan, M Eric Benbow

    Published 2025-01-01
    “…We make connections of LULC with environmental changes (e.g. soils) that likely lead to an increased risk of mycobacteria spillover to human and other animal populations. An important feature of our review is a focus on research from the richest countries of the world, though some studies have been done in Africa, Asia and South America. …”
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  19. 18979

    IGF2BP2 Shapes the Tumor Microenvironment by Regulating Monocyte and Macrophage Recruitment in Bladder Cancer by Jianpeng Li, Yunzhong Jiang, Minghai Ma, Lu Wang, Minxuan Jing, Zezhong Yang, Lizhao Wang, Quanpeng Qiu, Rundong Song, Yuanchun Pu, Yuanquan Zhang, Nan Mei, Mengzhao Zhang, Jinhai Fan

    Published 2024-12-01
    “…NicheNet analysis showed that GE‐9 cells interact with monocyte/macrophage populations through cytokine signaling. Co‐culture experiments confirmed IGF2BP2's role in recruiting macrophages, partially mediated by CCL2. …”
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    Article
  20. 18980

    Pathogen community composition and co-infection patterns in a wild community of rodents by Abbate, Jessica L., Galan, Maxime, Razzauti, Maria, Sironen, Tarja, Voutilainen, Liina, Henttonen, Heikki, Gasqui, Patrick, Cosson, Jean-François, Charbonnel, Nathalie

    Published 2024-02-01
    “…It is therefore important to know what pathogens naturally circulate in rodent populations, and to understand the factors that may influence their distribution in the wild. …”
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