Novel Pt (II) Complexes With Anticancer Activity Against Pancreatic Ductal Adenocarcinoma Cells by Erika Stefàno, Gianluca Rovito, Luca G. Cossa, Federica De Castro, Viviana Vergaro, Asjad Ali, Giulia My, Danilo Migoni, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…However, the development of resistance to chemotherapy drugs has created a need for the synthesis of new anticancer agents. Platinum-based drugs containing the bidentate ligand phenanthroline have been found to have strong antitumor activity due to their ability to cause DNA damage. …”
Get full text

Near-orientation deformation banding formation mechanism of Al-Mg-Mn-Er alloy by Hongfu Yang, Mengnie Li, Yaru Wu, Shumeng Lu, Rensong Huang, Shanju Zheng, Xiaohong Yuan, Yonghua Duan

Get full text

Reduction disintegration behavior and crystallographic transformation of vanadium–titanium magnetite pellets during hydrogen-based reduction by Feng Chen, Hao Li, Yufeng Guo, Kuo Liu, Shuai Wang, Lingzhi Yang, Yuekai Wen, Meng Zhang

Get full text

Immunotherapy as a neoadjuvant preoperative treatment for locally advanced pulmonary sarcomatoid carcinoma: a case report of clinical efficacy by Hanhan Li, Hanhan Li, Ruilian Chen, Wei Guo, Shang Xiang, Shang Xiang, Jiayang Huang, Jiayang Huang, Hanrui Chen

“…Studies have shown that the survival rate for advanced-stage patients is less than 5%, with a median overall survival (OS) of less than 6.5 months.Case reportHerein, we report a case of locally advanced PSC in a 56-year-old male patient who received platinum-based double-drug therapy combined with anti-angiogenic drugs, followed by immunotherapy as the first-line systemic treatment. …”
Get full text

In Vitro Evaluation of a Stable Monomeric Gold(II) Complex with Hematoporphyrin IX: Cytotoxicity against Tumor and Kidney Cells, Cellular Accumulation, and Induction of Apoptosis by Georgi Momekov, Dilyan Ferdinandov, Spiro Konstantinov, Sonja Arpadjan, Daniela Tsekova, Galina Gencheva, Panayot R. Bontchev, Margarita Karaivanova

“…In contrast, the solid tumor models are more sensitive to the platinum drug. A comparative assessment of both agents against the human kidney cell line 293T has shown that [Au(II)Hp-2H.…”
Get full text

Alginate Hydrogel Beads with a Leakproof Gold Shell for Ultrasound-Triggered Release by Marcus Flowers, Alex Paulsen, Claire R. W. Kaiser, Adam B. Tuma, Hubert H. Lim, Brenda M. Ogle, Chun Wang

“…<b>Methods:</b> The ALG is crosslinked into beads with calcium chloride and layered with a polycation to adjust the surface charge for the adsorption of catalytic platinum nanoparticles (Pt NPs). The coated bead is subject to electroless plating, forming a gold shell. …”
Get full text

Experimental and Modeling Study for the Solar-Driven CO₂ Electrochemical Reduction to CO by Matteo Agliuzza, Roberto Speranza, Andrea Lamberti, Candido Fabrizio Pirri, Adriano Sacco

“…A 2D model was designed, incorporating cathode and anode regions divided by an ion-exchange membrane. The model includes platinum foil and silver nanoparticles as catalysts for the oxygen evolution reaction and CO₂ reduction reaction, respectively. …”
Get full text

Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…The median progression-free survival (mPFS) on first-line platinum plus etoposide after the conversion to SCLC was 3.0 months. …”
Get full text

Elucidating deep-sea thermometric deviations and their consequences for oceanic heat content assessment via high-pressure calibration by Muzi Zhang, Muzi Zhang, Qingquan Sun, Qingquan Sun, Xiaoxue Bai, Xiaoxue Bai, Chi Wu, Chi Wu, Chi Wu

“…A high-precision pressure-temperature vessel was employed to simulate deep sea environments, conducting systematic pressure experiments with precise temperature control (0.5 mK) across a temperature range of -2 to 35°C and from atmospheric pressure to full ocean depth (0–12700 m). A Standard platinum resistance thermometer (SPRT), isolated from the pressure environment and placed adjacent to the SBE 3, served as a calibration reference throughout the experiments. …”
Get full text

Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting by Ming Liu, Li Zheng, Yang Zhang, Jinhui Tian

“…PA has potential for treating TNBC with the target of TOP2A, and platinum drug resistance possibly serving as the KEGG pathway through which PA exerts its therapeutic effects. …”
Get full text

Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells by Ambrož Martin, Šmatová Markéta, Šadibolová Michaela, Pospíšilová Eva, Hadravská Pavlína, Kašparová Michaela, Skarková Veronika Hanušová, Králová Věra, Skálová Lenka

“…The present study is designed to find out if sesquiterpenes, α-humulene (HUM), valencene (VAL), β-caryphyllene-oxide (CAO) and trans-nerolidol (NER), are able to improve the antiproliferative effect of classical cytostatic drugs, 5-fluorouracil (FU) and oxaliplatin (1,2-diaminocyclohexaneoxalato-platinum, OxPt), in colon cancer cell lines Caco-2 and SW-620. …”
Get full text

Multimodal treatment with Neoadjuvant chemotherapy for eyelid and periocular sebaceous gland carcinoma: Long-term outcomes by Vijitha S. Vempuluru, Anshika Luthra, Vijay Anand Reddy Palkonda, Swathi Kaliki

“…Conclusions and importance: The long-term outcomes in patients with eyelid and periocular SGC who achieve tumor control with platinum-based NACT seem promising.…”
Get full text

Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface by Bo Wen, Liang Shen, Xiaoyang Kang

“…To ensure consistent results, a novel micro-wire welding with platinum pad method was introduced during the welding process. …”
Get full text

Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells by Zheng Zhang, Huaxiang Xu, Junyi He, Qiangsheng Hu, Yuxin Liu, Zijin Xu, Wenhui Lou, Wenchuan Wu, Lei Zhang, Ning Pu, Chenye Shi, Yaolin Xu, Wenquan Wang, Liang Liu

“…These results reveal a critical role of KLF5 in sensitized chemotherapy of pancreatic cancer, and suggest that ferroptosis combined with platinum-based chemotherapy rather than gemcitabine-based chemotherapy is expected to bring better therapeutic effects.…”
Get full text

An Analysis and Research on the Transmission Ratio of Dye Sensitized Solar Cell Photoelectrodes by Using Different Etching Process by Chin-Guo Kuo, Cheng-Fu Yang, Mu-Jung Kao, Wen-Pin Weng, Chi-Cheng Chang, Lih-Ren Hwang, Jian-Lan Nil

“…After etching process, the TiO2 nanotube arrays were fabricated as the photoelectrode of DSSCs by electrochemical process, in which the Ti as anode and platinum (Pt) as cathode. The electrolyte solution included C2H4(OH)2, NH4F, and deionized water. …”
Get full text

Electrochemical Skin Conductance as a Marker of Painful Oxaliplatin-Induced Peripheral Neuropathy by Jean-Baptiste Delmotte, Abdulkarim Tutakhail, Kahina Abdallah, Pauline Reach, Marguerite D’Ussel, Gael Deplanque, Hélène Beaussier, François Coudoré

“…Purpose. Oxaliplatin is a platinum compound widely used in gastrointestinal cancer treatment but produces dose-limiting peripheral neuropathy. …”
Get full text

Determination of Atropine Sulfate in Human Urines by Capillary Electrophoresis Using Chemical Modified Electrode as Electrochemiluminescence Sensor by Min Zhou, Juan Mi, Yujie Li, Huashan Zhang, Yanjun Fang

“…A Ru(bpy)3 2+-based electrochemiluminescence (ECL) detection coupled with capillary electrophoresis (CE) was developed for the determination of atropine sulfate on the basis of an Eu-PB modified platinum electrode as the working electrode. The analyte was injected to separation capillary of 50 cm length (25 μm i.d., 360 μm o.d.) by electrokinetic injection for 10 s at 10 kV. …”
Get full text

Bismuth-Remaining Cupellation Fire Assay Preconcentration Combined with Inductively Coupled Plasma Mass Spectrometry for the Simultaneous Determination of Ultratrace Au, Pt, Pd, Ru... by Wenshan Ni, Xiangju Mao, Mingxing Yao, Qiliang Sun, Xiaorui Guo, Hongli Zhang, Lu Liu

“…In this work, a novel method of bismuth fire assay (Bi-FA) combined with inductively coupled plasma mass spectrometry (ICP-MS) simultaneous determination of ultratrace gold (Au), platinum (Pt), palladium (Pd), ruthenium (Ru), rhodium (Rh), and iridium (Ir) in geologic samples was established. …”
Get full text

Cost-effectiveness Analysis of Lorlatinib in Patients Previously Treated with Anaplastic Lymphoma Kinase Inhibitors for Non-small Cell Lung Cancer in Greece by George Gourzoulidis, Oresteia Zisimopoulou, Nadia Boubouchairopoulou, Christina Michailidi, Chrissy Lowry, Charalampos Tzanetakos, Georgia Kourlaba

“…**Objective:** The present study assessed the cost-effectiveness of lorlatinib vs pemetrexed with platinum combination of carboplatin or cisplatin (P-ChT) in Greece. …”
Get full text

Immunotherapy in Recurrent Ovarian Cancer by Keyao Chen, Jingjing Wang, Meng Yang, Shaoqiong Deng, Li Sun

“…The immune microenvironment in platinum-sensitive and -resistant cases exhibits distinct immunological profiles, influencing therapy outcomes. …”
Get full text