A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by Estrogen/Gestagen Therapy by Yoshihide Inayama, Koji Yamanoi, Baku Nakakita, Shimpei Shitanaka, Jumpei Ogura, Tsutomu Ohara, Mie Sakai, Haruka Suzuki, Koji Yasumoto, Ichiro Kishimoto, Yusuke Sagae, Yoshimi Kitawaki, Koh Suginami

“…Two years later, her pituitary hormonal status was evaluated in detail. …”
Get full text

Metabolic profile of blood serum in experimental arterial hypertension by A. A. Seryapina, A. A. Malyavko, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, A. L. Markel

“…The etiology of essential hypertension is intricate, since it employs simultaneously various body systems related to the regulation of blood pressure in one way or another: the sympathetic nervous system, renin-angiotensin-aldosterone and hypothalamic-pituitary-adrenal systems, renal and endothelial mechanisms. …”
Get full text

The Impact of Physical Activities on Male Fertility: A Systematic Review by Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Julia Białeta, Karolina Siembab, Katarzyna Rowińska, Michalina Jurkiewicz, Wiktor Garbarczyk, Wiktoria Pysiewicz, Agnieszka Napieralska

“…Another issue discussed is the negative impact of exercise on fertility, as well as injuries in the perineal region—some of which directly affect organs, surrounding tissues (such as nerves), and regulatory mechanisms like hypothalamic-pituitary-gonadal axis. Materials and Methods This study was conducted as a comprehensive literature review based on scientific articles and research papers accessed through two primary databases: PubMed and Google Scholar. …”
Get full text

Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes by Ye Zhang, Yanpeng Xing, Haibo Yuan, Xiaokun Gang, Weiying Guo, Zhuo Li, Guixia Wang

“…The impairment of hypothalamic-pituitary-adrenal axis activity may be one of the underlying mechanisms of the glycometabolic dysfunctions in OSA with T2DM patients.…”
Get full text

Severe reversible cardiomyopathy associated with adrenal crisis caused by isolated adrenocorticotropin deficiency: a case report by Li Wang, Fangfang Bu, Lanjie He, Guihua Yao, Guihua Yao

“…Isolated adrenocorticotropin deficiency (IAD) is a rare condition of pituitary adrenal insufficiency. In this case report, we describe a 74-year-old male patient who was in good physical health and was admitted to our hospital with a sudden onset of fever and confusion that was complicated by hyponatremia and hypotension. …”
Get full text

Epigenetics of suicidal behavior by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, S. B. Malykh, V. V. Viktorov, E. K. Khusnutdinova

“…Published data identified multiple genes including those involved in the functioning of serotonergic (SLC6A4, TPH, 5-HT1A), hypothalamic-pituitary-adrenal systems (FKBP5) and polyamines (SAT and OATL1) associated with suicidal behavior. …”
Get full text

Spawning biology, breeding, and larval rearing techniques for Xenentodon cancila (Hamilton) for aquaculture and recreational use in Bangladesh: The first approach by Paul Shyamal Kumar, Sarker Bhakta Supratim, Sultana Nahid, Pall Jewel Chandra, Perven Tania, Saha Debasish, Majumdar Priyanka Rani

“…Nine doses of common carp pituitary gland (CPG), human chorionic gonadotropin (HCG), and Ovaprim for breeding were administered, except in the control treatment that was without hormones. …”
Get full text

<i>Lin28b-let-7</i> Modulates mRNA Expression of <i>GnRH1</i> Through Multiple Signaling Pathways Related to Glycolysis in GT1-7 Cells by Yujing Xie, Xin Li, Meng Wang, Mingxing Chu, Guiling Cao

“…In this study, the mRNA expression levels of <i>Lin28b</i> and <i>let-7</i> in the pubertal and juvenile goat hypothalamus and pituitary gland were detected, and <i>Lin28b</i> expression in the pubertal hypothalamus decreased significantly compared with that in juvenile tissues. …”
Get full text

GH, IGF-1, and Age Are Important Contributors to Thyroid Abnormalities in Patients with Acromegaly by Xia Wu, Lu Gao, Xiaopeng Guo, Qiang Wang, Zihao Wang, Wei Lian, Wei Liu, Jian Sun, Bing Xing

“…The demographic and clinical information were recorded. Specimens of pituitary adenomas and thyroid cancer were collected for BRAF mutation assessments. …”
Get full text

Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…Aerobic exercise can alleviate the internal inflammation by relieving leptin resistance and may mitigate the sex hormone disorder and hyperandrogenism in rats with PCOS by affecting the hypothalamic-pituitary-ovarian axis.…”
Get full text

Transcriptome and DNA methylation analysis of the goat pineal gland during puberty by Bochao Zhang, Genbao Zhu, Jianling Wu, Huihui Xie, Jiankun Cui, Wei Qian, Qing Yi, Fuqiang Pan, Fugui Fang, Yinghui Ling, Yunhai Zhang, Yunsheng Li, Ya Liu

“…Abstract Previous studies have confirmed that methylation regulates gene transcription in the hypothalamus-pituitary-gonadal axis during puberty initiation, but little is known about the regulation of DNA methylation on gene expression in the pineal gland. …”
Get full text

Gaps in the management of adrenal insufficiency in melanoma survivors: a retrospective cohort studyResearch in context by Wei Lin, Wei Wang, F. Stephen Hodi, Le Min

“…Methods: This retrospective cohort study analyzed melanoma patients treated with immune checkpoint inhibitors (ICIs) with SAI (Mel_SAI, n = 161), without SAI (Mel_CON, n = 168), and patients with pituitary adenoma-related SAI (Pit_SAI, n = 106) at our institution from January 2013 to November 2023. …”
Get full text

Optical Coherence Tomography May Help Distinguish Glaucoma from Suprasellar Tumor-Associated Optic Disc by Michael Mimouni, Hadas Stiebel-Kalish, Irena Serov, Gabriel Chodick, Mohammad Zbedat, Dan D. Gaton

“…In this retrospective cross-sectional study, we collected data from the eyes of 25 patients with suprasellar craniopharyngioma or pituitary macroadenomas (group 1) and 35 patients with primary open-angle glaucoma (POAG) (group 2), seen between 2001 and 2015, all with a visual acuity of ≥20/40, for whom Stratus Time-Domain (TD) optic nerve OCT scans were available. …”
Get full text

Evaluating ovarian follicles and their steroid hormone gene expression patterns in a high egg-producing research turkey line by George B. Hall, Diane Hildenberger, Julie A. Long, Kristen Diehl

“…In both cases changes in pituitary hormone receptor transcription levels appeared to affect the steroid hormone synthesis pathway. …”
Get full text

Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP) by Xiaoqian Zhou, Weifeng Liu, Bailin Cong, Aifang Deng, Jing Lin, Linlin Zhao, Shenghao Liu

“…Moreover, acute exposure to TCEP regulated MAPK-mediated transduction and regulation of GnRH signaling, thereby altering the expression of hypothalamic-pituitary-gonadal (HPG) axis-related genes. Conclusions These findings revealed the endocrine disrupting effects of TCEP on turbot and identified biomarkers related to reproductive toxicity, providing early warning for the monitoring of healthy aquaculture.…”
Get full text

What is the relationship between exposure to environmental pollutants and severe mental disorders? A systematic review on shared biological pathways by Pierluigi Catapano, Mario Luciano, Salvatore Cipolla, Daniela D'Amico, Alessandra Cirino, Maria Chiara Della Corte, Gaia Sampogna, Andrea Fiorillo

“…Studies carried out with humans, which are mainly focused on measuring the impact of particulate matter (PM2.5 and PM10) exposure on mental health, showed an increased risk of depression or psychotic relapses through the inflammation and oxidative stress pathways, or through the alteration of the hypothalamic-pituitary-adrenal (HPA) axis. Animal models showed the potential impact of pollution on brain functioning through increased inflammatory responses, oxidative stress, HPA axis disruption, hippocampal damage, and neurotransmitters dysregulation. …”
Get full text

Prolactin Is a Strong Candidate for the Regulation of Luteal Steroidogenesis in Vizcachas (Lagostomus maximus) by S. Proietto, S. A. Cortasa, M. C. Corso, P. I. F. Inserra, S. E. Charif, A. R. Schmidt, N. P. Di Giorgio, V. Lux-Lantos, A. D. Vitullo, V. B. Dorfman, J. Halperin

“…We found that, although the expression of pituitary PRL increased steadily during pregnancy, its ovarian receptor (PRLR) reached its maximum in midpregnancy and drastically decreased at term pregnancy. …”
Get full text

SAlexNet: Superimposed AlexNet using residual attention mechanism for accurate and efficient automatic primary brain tumor detection and classification by Qurat-ul-ain Chaudhary, Shahzad Ahmad Qureshi, Touseef Sadiq, Anila Usman, Ambreen Khawar, Syed Taimoor Hussain Shah, Aziz ul Rehman

“…In this work, we propose Superimposed AlexNet (SAlexNet-1 and its extension SAlexNet-2) to detect the malignancy of primary brain tumors (Glioma, Meningioma, and Pituitary) by incorporating three enhancements: (1) fusing Hybrid Attention Mechanism (HAM), (2) dense feature extraction by replacing initial convolution 11 × 11 layer with multiple convolution 3 × 3 layers for extra non-linearity alleviating parameter burden, and (3) pretraining the encoder path on a correlated dataset via semi-transfer learning (STL) enhancing model performance. …”
Get full text

GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 by Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo

“…Abstract Reproductive hormones associated with the hypothalamic-pituitary-gonadal (HPG) axis are closely linked to bone homeostasis. …”
Get full text

The Optimum Dietary Phenylalanine Requirement of Hybrid Grouper (Epinephelusfuscoguttatus ♀ × Epinepheluslanceolatus ♂) Juveniles: Effects on Growth Performance, Gut Micromorpholog... by Pinxian Yang, Haijiao Wang, Lei Ma, Haoran Yin, Zhanying Zhu, Cong Liu, Wei Huang, Zhiyu Zhou, Xiaoyi Wu, Sehrish Taj

“…The Phe 10.1 group exhibited higher growth hormone (GH) expression in the pituitary compared to other groups. Expression of hepatic insulin-like growth factor-1 (IGF-1) and growth hormone receptor 1 (GHR1) displayed a similar pattern of variation to that of GH. …”
Get full text