A Case of Apoplexy of Rathke’s Cleft Cyst Followed by Cerebral Infarction by Yu-ichiro Ohnishi, Yasunori Fujimoto, Koichi Iwatsuki, Toshiki Yoshimine

“…The change of the density in the suprasellar region on CT suggested the pituitary apoplexy. CT also showed a low density area in the territory of the right middle cerebral artery, which indicated the cerebral infarction. …”
Get full text

Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders” by Koji Hori, Kimiko Konishi, Misa Hosoi, Hiroi Tomioka, Masayuki Tani, Yuka Kitajima, Mitsugu Hachisu

“…Moreover, based on a case report of a patient with mild AD and slightly deteriorated ACh, we also speculate that AA can appear endogenously in Lewy body disease due to the dual action of the downregulation of ACh and hyperactivity of the hypothalamic-pituitary-adrenal axis. Based on these hypotheses, we consider AA to be a behavioral pathology of Lewy body disease. …”
Get full text

Immune Aspects and Myometrial Actions of Progesterone and CRH in Labor by Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Panayiotis Tsikouras, Zoe Iliodromiti

“…Placental CRH acts on the fetal pituitary-adrenal axis to stimulate adrenal production of androgens and cortisol and also acts directly on myometrial cells via its receptors. …”
Get full text

Combined Dexamethasone Suppression-Corticotropin-Releasing Hormone Stimulation Test in Studies of Depression, Alcoholism, and Suicidal Behavior by Leo Sher

“…The hypothalamic-pituitary-adrenal (HPA) axis controls the secretion of corticotropin-releasing hormone (CRH), corticotropin (adrenocorticotropic hormone, ACTH), and cortisol. …”
Get full text

Psychobiotic effects of probiotics and prebiotics by V. T. Ivashkin, K. V. Ivashkin

“…Intestinal microbiome is a factor of hypothalamic-pituitary-adrenal axis formation that is involved in regulation of immunomodulation, lipid metabolism, energy balance and electrophysiologic activity of enteric nervous system. …”
Get full text

Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer by Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang

“…Adaptive cell therapy, cancer vaccines, gene therapy, and monoclonal antibody therapy have all been used in gastric cancer with some initial success. PTTGs (pituitary tumor-transforming genes) have been proven to be closely related to the prognosis of many malignant tumors. …”
Get full text

Multiple Endocrine Neoplasia Type 1 with Concomitant Existence of Malignant Insulinoma: A Rare Finding by Randhir Sagar Yadav, Ashik Pokharel, Deepshikha Gaire, Shumneva Shrestha, Ashbita Pokharel, Sumita Pradhan, Prasan Bir Singh Kansakar

“…Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome of autosomal dominant inheritance defined by co-occurrence of two or more tumors originating from the parathyroid gland, pancreatic islet cells, and/or anterior pituitary. Insulinoma which has an incidence of 0.4% is a rare pancreatic neuroendocrine tumor. …”
Get full text

Challenges in diagnosis and treatment of cushing disease in a 12-year-old boy. Case report by Agim Gjikopulli, Sonila Tomori, Marjeta Tanka, Donjeta Bali

“… Cushing’s Disease (CD), defined as hypercortisolism caused by excess Adrenocorticotropic Hormone (ACTH) secretion by a pituitary corticotroph adenoma, rarely presents in the pediatric age range. …”
Get full text

Hubungan antara Stres dengan Pola Siklus Menstruasi Mahasiswi Fakultas Kedokteran Universitas Andalas by Nurul Aini Yudita, Amel Yanis, Detty Iryani

“…Stres merangsang  hypothalamus-pituitary-adrenal  cortex  aksis  sehingga  dihasilkan hormon kortisol. …”
Get full text

The Decreased Growth Hormone Response to Growth Hormone Releasing Hormone in Obesity Is Associated to Cardiometabolic Risk Factors by Fernando Cordido, Jesús Garcia-Buela, Susana Sangiao-Alvarellos, Teresa Martinez, Ovidio Vidal

“…These data strongly suggest a role for insulin resistance in the decreased GH secretion of obesity and that the blunted GH secretion of central obesity could be the pituitary expression of the metabolic syndrome.…”
Get full text

A Rare Case of Functioning Adrenocortical Oncocytoma Presenting as Cushing Syndrome by Nicola Tartaglia, Pasquale Cianci, Amedeo Altamura, Vincenzo Lizzi, Fernanda Vovola, Alberto Fersini, Antonio Ambrosi, Vincenzo Neri

“…Generally, these tumors originate in the kidneys, thyroid, parathyroid, and salivary or pituitary glands; they have also been reported in other sites including choroid plexus, respiratory tract, and larynx. …”
Get full text

Comparison of natural and artificial vasopressin deficiency: why the latter is lethal? by D. Zelena

“…The V1b receptor on the anterior pituitary has a role in stress adaptation. The V2 subtype is located in the kidney and contributes to the antidiuresis. …”
Get full text

Clinical Presentation and Magnetic Resonance Findings in Sellar Tuberculomas by Dulce Bonifacio-Delgadillo, Yolanda Aburto-Murrieta, Citlaltepetl Salinas-Lara, Julio Sotelo, Ivonne Montes-Mojarro, Arturo Garcia-Marquez

“…The tuberculous infection of the pituitary gland and sellar region is characterized by the presence of an acute or chronic inflammatory reaction and may occur in the absence of systemic tuberculosis. …”
Get full text

The silent pandemic of stress: impact on menstrual cycle and ovulation by Mariam Saadedine, Sarah L. Berga, Stephanie S. Faubion, Chrisandra L. Shufelt

“…The collective health burden underscores the need for clinical awareness and comprehensive treatment strategies addressing behavioral and biopsychosocial stressors that lead to chronic hypothalamic-pituitary-adrenal (HPA) axis activation. Despite its prevalence and numerous adverse health consequences, research on this condition remains limited, revealing a significant gap in understanding and addressing this condition. …”
Get full text

Giant prolactinoma with progressive cranial settling and central herniation: a case report by Taha Shahbazi, Soheil Abdollahi Yeganeh, Shiva Borzouei, Mahdi Arjipour

“…Abstract Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. …”
Get full text

Late-Onset Isolated Corticotrope Deficiency in a Woman with Down Syndrome by Ibtissem Oueslati, Marwa Ben Jemaa, Meriem Yazidi, Fatma Chaker, Melika Chihaoui

“…ACTH level was normal, indicating corticotrope deficiency. Other pituitary hormones were normal. Magnetic resonance imaging scan revealed a partially empty sella turcica. …”
Get full text

Results of Gamma Knife Radiosurgery in Acromegaly by Alberto Franzin, Giorgio Spatola, Marco Losa, Piero Picozzi, Pietro Mortini

“…Eight patients (7.8%) experienced a new deficit of pituitary function. New cases of hypogonadism, hypothyroidism, and hypoadrenalism occurred in 4 of 77 patients (5.2%), 3 of 95 patients (3.2%), and 6 of 100 patients at risk (6.0%), respectively. …”
Get full text

Cushing’s disease with twin pregnancy and diabetes mellitus: a case report and literature review by Hideyasu Asai, Ikuo Yamamori, Shigeru Hagimoto, Kyoichi Okumura, Koki Sakakibara

“…A 38-year-old Japanese woman with a history of abnormal thyroid function of non-autoimmune origin, pituitary endocrine tumor, and untreated diabetes mellitus was referred to our outpatient clinic when she became pregnant with twins. …”
Get full text

Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome by Luciana Tock, Gláucia Carneiro, Andrea Z. Pereira, Sérgio Tufik, Maria Teresa Zanella

“…Our results show an increased adrenocortical production in nonobese PCOS women, not related to IR and associated with a normal hypothalamic-pituitary-adrenal suppression. Higher LH levels might be involved in this event.…”
Get full text

Axenfeld-Rieger Syndrome Associated with Congenital Glaucoma and Cytochrome P4501B1 Gene Mutations by Mukesh Tanwar, Tanuj Dada, Rima Dada

“…Mutations in the cytochrome P4501B1 (CYP1B1) gene have been reported to be associated with primary congenital glaucoma and other forms of glaucoma and mutations in pituitary homeobox 2 (PITX2) gene have been identified in ARS in various studies. …”
Get full text