Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism by Deborah Chiabrando, Emanuela Tolosano

“…FLVCR1-null mice show a phenotype resembling that of DBA patients, including erythroid failure and malformations. …”
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Role of microglia in the pathogenesis of multiple sclerosis and links to immunomodulatory therapy by P. Valiukevičius, R. Liutkevičienė, R. Balnytė

“…In response to environmental factors, microglia can acquire an inflammatory or anti-inflammatory phenotype. Microglia also play an important role in the pathogenesis of multiple sclerosis, and these cells are thought to be involved in both demyelination and remyelination processes. …”
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Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling by Anxhela Habibi, Wolfram Ruf, Leon Schurgers

“…During vascular repair, vascular smooth muscle cells (VSMCs) will switch from a contractile to a synthetic reparative phenotype. During prolonged vascular stress, VSMCs acquire a pathological phenotype leading to cardiovascular disease. …”
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Proximal Myopathy due to m.5835G>A Mutation in Mitochondrial MT-TY Gene by C. Simoncini, V. Montano, G. Alì, R. Costa, G. Siciliano, M. Mancuso

“…Furthermore different mutation can manifest with similar clinical phenotypes, making the genotype-phenotype correlation difficult. …”
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Bacterial contamination in public transport during COVID-19 pandemic: Characterization of an unusual Staphylococcus aureus isolate tolerant to vancomycin by Eva Smelikova, Marcela Krutova, Vaclav Capek, Marie Brajerova, Pavel Drevinek, Jan Tkadlec

“…Population analysis profile-area under the curve ratio (PAP-AUC) testing did not confirm the hVISA phenotype, but mutations in the hVISA phenotype-related gene vraR and other genes related to cell wall synthesis (fmtB) and intercellular adhesion (sasC) were found. …”
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Anthropometric profile of the brazilian male judo team: cross-sectional study by André Luíz Lopes, Gustavo dos Santos Ribeiro, Bruno Costa Teixeira, Randhall Bruce Carteri, Paulo Cavalcante Muzy, André Pontes-Silva

“…Results: The data indicate a very large effect size for the bone-muscle index (d = 2.72) and the mesomorphic phenotype (d = 1.33) in judokas and students. Large effect sizes were observed for muscle mass (d = 1.12), fat mass (d = -0.91), and the ectomorphic phenotype (d = -0.88). …”
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Transition Yet Energy Consuming for Tumor Growth Regulated by the Colored Microenvironment by Leiyan Chen, Yan Wang, Qingqing Li, Haohua Wang

“…Here, focusing on the regulatory role of noises from its strength and correlation time on phenotypic diversity of tumors, we show that (1) when the noise strength (NS) is fixed, extending the autocorrelation time (AT) of multiplicative noise can regulate bidirectionally the tumor phenotype, i.e., it can promote the diffusion also contribute to killing cancer cells simultaneously; (2) AT of additive noise can reduce the occurrence probability of cancer cells, but the NS can increase this probability; (3) the effect of the cross-correlated strength (CS) on cell phenotype is twofold, i.e., increasing CS may urge the mean first passage time (MFPT) of switching to the tumor state to have the minimum and maximum values but the cross-correlation time (CT) always makes the MFPT to have a minimum value. …”
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Molecular systematics of Keratinophyton: the inclusion of species formerly referred to Chrysosporium and description of four new species by Roman Labuda, Andreas Bernreiter, Doris Hochenauer, Alena Kubátová, Hazal Kandemir, Christoph Schüller

“…All four new species can be well distinguished from other species in the genus based on phenotype characteristics alone. Ten new combinations are proposed for Chrysosporium species which are resolved in the monophyletic Keratinophyton clade. …”
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Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium by Fawaz Abomaray, Sebastian Gidlöf, Cecilia Götherström

“…Stromal cells from endometriotic ovarian cysts (ESCcyst) and endometrium (ESCendo) were examined if they exhibited a MSC phenotype. Then, ESC were phenotypically examined for protein and gene expression of immunosuppressive and immunostimulatory molecules. …”
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12q14 Microdeletions: Additional Case Series with Confirmation of a Macrocephaly Region by Adrian Mc Cormack, Cynthia Sharpe, Nerine Gregersen, Warwick Smith, Ian Hayes, Alice M. George, Donald R. Love

“…This patient’s deletion is unique and hence defines a likely macrocephaly locus that contributes to the general phenotype characterising the 12q14 syndrome.…”
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The influence of prenatal environmental conditions on the weight of newborn domestic pigs by S. V. Nikitin, S. P. Knyazev, V. I. Ermolayev

“…Our investigation found that the relative contribution of environmental conditions during prenatal development into newborn weight variation is equal to 0.4717, the contribution of genotypic component is 0.4032; the contribution of interaction between environmental conditions and ambivalence of the “genotype–phenotype” relationships is 0.0846, indeterminacy of phenotypic realization of the littermate’s genotypes is 0.0405. …”
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Dynamic development of microglia and macrophages after spinal cord injury by Hu-Yao Zhou, Xia Wang, Yi Li, Duan Wang, Xuan-Zi Zhou, Nong Xiao, Guo-Xing Li, Gang Li

“…Our results showed that microglia were activated to a pro-inflammatory phenotype immediately after spinal cord injury, gradually transforming to an anti-inflammatory steady state phenotype as the disease progressed. …”
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Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two Chinese Han Families by Pengcheng Xu, Jun Xu, Hu Peng, Tao Yang

“…Intrafamilial cosegregation of the mutations with the hearing phenotype was confirmed in both families by the Sanger sequencing. …”
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Diagnosis and Management of the Overlap Syndromes of Autoimmune Hepatitis by Albert J Czaja

“…These cholestatic phenotypes have been designated ‘overlap syndromes’.…”
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Changes in the Diaphragm Lipid Content after Administration of Streptozotocin and High-Fat Diet Regime by Bartlomiej Lukaszuk, Agnieszka Miklosz, Malgorzata Zendzian-Piotrowska, Beata Wojcik, Jan Gorski, Adrian Chabowski

“…In comparison to other skeletal muscles, it is distinguished by an oxidative phenotype and uninterrupted cyclic contraction pattern. …”
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Too Aggressive Drop in Blood Pressure in a Hypertensive Male Leading to “Man-in-the-Barrel Syndrome” by Chamara Dalugama, Achila Jayasinghe, Udaya Ralapanawa, Shamali Abeygunawardena, Thilak Jayalath

“…“Man-in-the-barrel syndrome” is a neurological phenotype with brachial diplegia, normal sensation, and preserved motor function of the lower limb. …”
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Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct by Wattanapitayakul Suvara K., Chularojmontri Linda, Schäfer-Korting Monika

“…UVB significantly induced the aging phenotype in keratinocytes and impaired epidermal development. …”
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Effect of carbon nanoparticles in enhancing the vegetative propagation of Orthosiphon aristatus by Dhivya Viswanathan, Ranjani Soundhararajan, Hemalatha Srinivasan

“…The effect of synthesized CNPs on the plant phenotype were examined for growth metrics including the number of new leaves formed, increase in aerial height of stem cuttings, number of nodes, leaf area, and root length. …”
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Picking interstitial lung disease out of the myositis haystack by Jennifer Hannah, Harsha Gunawardena

“…It is clear than certain clinical and serological features phenotype patients into more specific CTD-IIM ILD subgroups. …”
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Effect of amniotic fluid on hair follicle growth by Gamze Tumentemur, Elif Ganime Aygun, Bulut Yurtsever, Didem Cakirsoy, Ercument Ovali

“…The study examined HF regeneration, transition to the anagen phase, and macrophage polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype.Results: Both FAF and FAFI treatments significantly increased HF density, with FAFI exhibiting enhanced effects. …”
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