Blood proteomics and multimodal risk profiling of human volunteers after incision injury: A translational study for advancing personalized pain management after surgery by Daniel Segelcke, Julia R. Sondermann, Christin Kappert, Bruno Pradier, Dennis Görlich, Manfred Fobker, Jan Vollert, Peter K. Zahn, Manuela Schmidt, Esther M. Pogatzki-Zahn

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Order reduction for an RNA virus evolution model by Andrei Korobeinikov, Aleksei Archibasov, Vladimir Sobolev

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Sensitive windows for within- and trans-generational plasticity of anti-predator defences by Tariel-Adam, Juliette, Luquet, Émilien, Plénet, Sandrine

Subjects: “…timing of exposure; sensitive windows; critical windows; predator-prey interactions; Physa acuta; phenotypic plasticity; transgenerational effects; inducible defences…”
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Antimicrobial resistance in clinical <I>Escherichia coli</I> isolates obtained from animals by M. N. Isakova, O. V. Sokolova, N. A. Bezborodova, A. S. Krivonogova, A. G. Isaeva, V. D. Zubareva

Subjects: “…phenotypic and genetic resistance…”
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Ranking the VIR collection of maize (Zea mays L.) according to the traits valuable for breeding in the soil and climate environments of the Republic of Belarus by Ye. M. Govor, E. B. Khatefov

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Characteristics of Sluggish Cognitive Tempo among adults with ADHD: objective neurocognitive measures align with self-report of executive function by Beth Krone, Lenard A. Adler, Deepti Anbarasan, Terry Leon, Richard Gallagher, Pooja Patel, Stephen V. Faraone, Jeffrey H. Newcorn

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Drug-Induced Liver Injuries (Clinical Guidelines for Physicians) by Vladimir T. Ivashkin, Andrey Yu. Baranovsky, Karina L. Raikhelson, Lyudmila K. Palgova, Marina V. Maevskaya, Elina A. Kondrashina, Natalya V. Marchenko, Tatyana P. Nekrasova, Igor G. Nikitin

Subjects: “…drug-induced liver injury phenotypes…”
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Anxiety and neurometabolite levels in the hippocampus and amygdala after prolonged exposure to predator-scent stress by O. B. Shevelev, V. E. Tseilikman, N. V. Khotskin, А. S. Khotskina, G. V. Kontsevaya, M. S. Lapshin, M. P. Moshkin, M. V. Komelkova, I. V. Feklicheva, O. B. Tseilikman, E. B. Manukhina, H. F Downey, E. L. Zavjalov

“…According to the peculiarities of behavioral reactions to a stressor, animals were retrospectively divided into two phenotypes. The first phenotype used a passive behavioral strategy, and the second phenotype was active. …”
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Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF) by Huah Shin Ng, Richard Woodman, Nicola Veronese, Alberto Pilotto, Arduino A. Mangoni

“…In contrast, the risk of mortality in phenotype 2 was not different to phenotype 1.Conclusion We observed an association between comorbidity phenotypes identified using LCA and mortality in older AF patients. …”
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Differential risk of cardiovascular complications in patients with type-2 diabetes mellitus in Ghana: A hospital-based cross-sectional study. by Christian Obirikorang, Evans Asamoah Adu, Anthony Afum-Adjei Awuah, Samuel Nkansah Darko, Frank Naku Ghartey, Samuel Ametepe, Eric N Y Nyarko, Enoch Odame Anto, William Kwame Boakye Ansah Owiredu

“…These groups included the obesity-related phenotype, the severe insulin resistance phenotype, and the normal weight phenotype with improved insulin resistance. …”
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Role of T-Cell Polarization and Inflammation and Their Modulation by n-3 Fatty Acids in Gestational Diabetes and Macrosomia by A. Hichami, O. Grissa, I. Mrizak, C. Benammar, N. A. Khan

“…Th (T helper) cells are differentiated into either Th1 or Th2 phenotype. It is generally considered that Th1 phenotype is proinflammatory, whereas Th2 phenotype exerts anti-inflammatory or protective effects. …”
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8q22.2q22.3 Microdeletion Syndrome Associated with Hearing Loss and Intractable Epilepsy by Alejandra Rincon, Paola Paez-Rojas, Fernando Suárez-Obando

“…We discuss the clinical phenotype of the patient presenting relevant findings like hearing loss and severe epilepsy and the possible relations between the phenotype and the genes involved in the microdeletion. …”
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Metabolic health and global cardiovascular risk in obese patients. Endocrinology Service. Cienfuegos, 2021-2022 by Leonelsy Núñez García, Elodia María Rivas Alpízar

“…A significant association was evident between global cardiovascular risk and the condition of having a metabolically unhealthy obese phenotype compared to healthy people.<br /><strong>Conclusions:</strong> the metabolically unhealthy obese phenotype was shown in more than half of the studied participants; the interaction of biological elements with unhealthy lifestyle is related to global cardiovascular risk in the metabolically unhealthy obese phenotype regarding the healthy.…”
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Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations by Nele Niebrügge, Olga Trovato, Roman Praschberger, Andreas Lieb

“…<b>Conclusions:</b> Although our results indicate that the interaction of the two variants with the most highly expressed heterotrimeric G-protein complex subunit combinations also results in a gain-of-function phenotype, they also clearly demonstrate that the phenotype can be significantly altered, dependent on heterotrimeric G-protein complex expression.…”
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Serum Levels of LL-37 and Inflammatory Cytokines in Plaque and Guttate Psoriasis by Young Ji Hwang, Ho Jung Jung, Min Jung Kim, Nam Kyung Roh, Jae Wook Jung, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn

“…It is assumed that the plaque phenotype of psoriasis is associated with T helper (Th) 1 immune response activation, while the guttate phenotype is associated with the Th17 immune response. …”
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Severe Psychomotor Delay in a Severe Presentation of Cat-Eye Syndrome by Guillaume Jedraszak, Aline Receveur, Joris Andrieux, Michèle Mathieu-Dramard, Henri Copin, Gilles Morin

“…The phenotype was atypical and included a severe developmental delay. …”
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Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures by Natalia Malek, Katarzyna Popiolek-Barczyk, Joanna Mika, Barbara Przewlocka, Katarzyna Starowicz

“…Microglial activation is a polarized process divided into potentially neuroprotective phenotype M2 and neurotoxic phenotype M1, predominant during chronic neuroinflammation. …”
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Choline Phospholipid Metabolites of Human Vascular Endothelial Cells Altered by Cyclooxygenase Inhibition, Growth Factor Depletion, and Paracrine Factors Secreted by Cancer Cells by Noriko Mori, Kshama Natarajan, V. P. Chacko, Dmitri Artemov, Zaver M. Bhujwalla

“…Treatment of cancer cells with the anti-inflammatory agent, indomethacin (INDO), reverted the phenotype of choline phospholipid metabolites in cancer cells towards a less malignant phenotype. …”
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Current Progress in the Rejuvenation of Aging Stem/Progenitor Cells for Improving the Therapeutic Effectiveness of Myocardial Repair by Gurleen Kaur, Chuanxi Cai

“…Overall, improving the intrinsic properties of aging stem cells as well as the surrounding environment allows these cells to adopt a phenotype similar to their younger counterparts.…”
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Disease Stage-Associated Alterations in Learning and Memory through the Electroacupuncture Modulation of the Cortical Microglial M1/M2 Polarization in Mice with Alzheimer’s Disease... by Long Li, Le Li, Jiayong Zhang, Sheng Huang, Weilin Liu, Zhifu Wang, Shengxiang Liang, Jing Tao, Lidian Chen

“…Microglia seemingly demonstrate two contradictory phenotypes in response to different microenvironmental cues, the M1 phenotype and the M2 phenotype, which are detrimental and beneficial to pathogenesis, respectively. …”
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