Evaluation of Vitrectomy with Planned Foveal Detachment as Surgical Treatment for Refractory Diabetic Macular Edema with or without Vitreomacular Interface Abnormality by Ahmed M. Abdel Hadi

“…Moreover, cases with VMA resistant to pharmacotherapy was shown to respond well to this technique. …”
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Defining pediatric polypharmacy: A scoping review. by Paul M Bakaki, Alexis Horace, Neal Dawson, Almut Winterstein, Jennifer Waldron, Jennifer Staley, Elia M Pestana Knight, Sharon B Meropol, Rujia Liu, Hannah Johnson, Negar Golchin, James A Feinstein, Shari D Bolen, Lawrence C Kleinman

“…Commonly used terms included polypharmacy, polytherapy, combination pharmacotherapy, average number, and concomitant medications. …”
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Massive Central Pulmonary Embolism with Riding Embolus and Concomitant Aortic Arch Embolism—Should We Diagnose Patients Earlier for Blood Clotting Disorders? Case Report by Anna Lis, Paweł Kowalski, Marcin Wita, Tomasz Zawadzki, Tomasz Ilczak, Wojciech Żurawiński, Mateusz Majewski

“…After several days of hospitalisation and the conversion of pharmacotherapy to oral anticoagulants, the patient was discharged home in a stable condition with recommendations for further follow-up in appropriate clinics. …”
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Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models by Neel Deferm, Neel Deferm, Jean Dinh, Jean Dinh, Amita Pansari, Masoud Jamei, Khaled Abduljalil

“…IntroductionPharmacotherapy during lactation often lacks reliable drug safety data, resulting in delayed treatment or early cessation of breastfeeding. …”
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Resource constraints, patient emotions, and therapy: experiences of healthcare providers in the screening and management of gestational diabetes mellitus in northern Ghana by Mohammed Bukari, Abdulai Abubakari, Hawa Malechi, Thomas Hinneh, Humphrey Garti, Faith Agbozo

“…The second theme was care-centred experiences, which explored patient emotions during GDM care, and the care they receive post-GDM diagnosis, with subthemes namely: raw emotions, non-pharmacological therapy, and pharmacotherapy. Conclusion Findings suggest the need for health system strengthening through the training and recruitment of dedicated skilled personnel, as well as government intervention through policy revision to cover the cost of GDM diagnostic tests. …”
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STATISTICAL METHODS TO IMPROVE THE QUALITY ASSESSMENT OF CLINICAL AUDIT RESULTS by Taras Gutor, Andriy Zimenkovsky, Zoriana Mysak

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Medication non-adherence and its predictors among patients with bipolar disorder in Northwest Ethiopia by Fasil Bayafers Tamene, Endalamaw Aschale Mihiretie, Tirsit Ketsela Zeleke, Ashenafi Kibret Sendekie, Eyayaw Ashete Belachew, Samuel Agegnew Wondm

“…Abstract While pharmacotherapy is the primary approach for treating patients with bipolar disorder, non-adherence is the most common barrier preventing these patients from achieving optimal medication effectiveness. …”
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The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases by Meaghan Roach, Natalie Land, Jennifer Hernandez, Reina Rau, Jacquelyn W. Chou, Stacey S. Hickson, Danielle F. Rollmann, J. Ross Maclean

“…However, the extent to which pharmacotherapies are represented as treatment options in guideline recommendations has not been well elucidated. …”
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Medical treatment of patients before surgical myocardial revascularization by I.V. Shklianka, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…The specificity of preoperative usage of some cardiovascular pharmacotherapy agents in comparison to the basic treatment of stable ischemic heart disease is analyzed in detail. …”
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Sexual dimorphism in the response to antidepressant therapy: Biological basis and clinical implications declaration of competing interests author contributions by Nedeljković Jelena, Stanić Dušanka, Petrović Jelena, Ivanović Ana, Ilić Miloš, Nikolašević-Stojković Gorana, Pejušković Bojana, Pešić Vesna

“…While conventional pharmacotherapy remains pivotal, personalized approaches that integrate psychotherapeutic modalities such as cognitive-behavioral therapy and mindfulness-based interventions have increased in recent years. …”
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Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis by Elisa Pasini, Cristina Baciu, Marc Angeli, Bianca Arendt, Diogo Pellegrina, Jüri Reimand, Keyur Patel, George Tomlinson, Mohammad T. Mazhab-Jafari, Lakshmi P. Kotra, Sandra Fischer, Johane P. Allard, Atul Humar, Mamatha Bhat

“…Metabolic dysfunction-associated steatohepatitis (MASH) has become the leading cause of chronic liver disease, but there has been no approved pharmacotherapy to date. Methods. We used a network analysis approach to delineate protein-protein interactions that contribute to the transition from steatosis to MASH, in order to identify and target this transition as a potential pharmacotherapeutic strategy. …”
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In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs by Amro A. Abdelazim, Mohamad Maged, Ahmed I. Abdelmaksoud, Sameh E. Hassanein

“…Cataloguing deleterious SNPs is essential for personalized gene-based pharmacotherapy.…”
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Irritable Bowel Syndrome: What Are the Reasons for Dissatisfaction with the Treatment of Patients and Doctors? (Based on the Experience of Medical Institutions of the Northwestern... by A. Yu. Baranovsky, T. V. Reshetova, I. S. Sakeyan

“…In each of these groups, three subgroups were formed: Subgroup 1 — treatment of patients with gastroenterological drugs; Subgroup 2 — treatment with combined pharmacotherapy (with the appointment of psychotropic drugs); Subgroup 3 — treatment with a combination of gastroenterological and psychotropic drugs and the use of non-medicinal methods of psychotherapy.Results. …”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

“…Patients with first-episode MDD with no history of antidepressant exposure and other medical comorbidity were recruited for pharmacotherapy with escitalopram, a first-line antidepressant. …”
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Enhancing work life through social cognition: the effect of SCIT in bipolar disorder by Zeynep Anaforoglu Bikmaz, Zeynep Mackali, Sibel Cakir

“…The effects of SCIT intervention with standard treatment methods were investigated on social cognition and functioning effects, which are often negatively affected in patients with BD-I.MethodsThe research involved 28 participants, allocated into two groups: An experimental group (n = 12) receiving SCIT for 8 weeks alongside standard treatments (pharmacotherapy and psychiatric interviews), and a control group (n = 16) undergoing standard treatment without additional interventions. …”
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Mental Disorders in Children and Adolescents in Crisis Situations: The Impact of the COVID-19 Pandemic and Armed Conflicts - Types of Disorders, Effects, and Intervention Strategie... by Katarzyna Gadżała, Sabina Przygodzka, Maciej Rutkiewicz, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…The basic strategy for preventing the occurrence and reducing the severity of these disorders are preventive programs, psychoeducation, psychotherapy, if necessary combined with pharmacotherapy. …”
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Managing Post COVID-19 Patient with Breathlessness by Yen Shen Wong, Muhammad Amin Ibrahim, Mohd Arif Mohd Zim, Mohd Fauzi Abdul Rani

“…He received oral baricitinib and intravenous methylprednisolone for 3 days, which was then followed by tapering prednisolone starting dose of 1 mg/kg/day (60 mg/day) with reduction of 10 mg prednisolone every 3 days. COPD pharmacotherapy was optimized with early utilization of dual bronchodilators and inhaled corticosteroid was withheld. …”
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Exercise Intervention in Women with Fibromyalgia and Its Influence on Pain, Psychological Variables, and Disability: An Observational Study by María Elena González-Álvarez, Víctor Riquelme-Aguado, Giacomo Rossettini, Josué Fernández-Carnero, Jorge Hugo Villafañe

“…Physical exercise has shown promise in modulating pain and improving physical function without the drawbacks of pharmacotherapy. This study aims to examine the effects of a 6-week telerehabilitation combined exercise program—including mobility, strength, and high-intensity exercises—on pain, psychological variables, and disability in women with fibromyalgia. (2) Methods: In this observational study involving 53 FM patients, the outcomes measured were the pressure pain threshold (PPT), the conditioned pain modulation (CPM) paradigm, levels of pain on the measurement day and the average of the last week (using NRS) the impact of the fibromyalgia (using Fibromyalgia Impact Questionnaire (FIQ), and anxiety (using the Spanish version of the State–Trait Anxiety Inventory—STAI). (3) Results: Statistically significant changes were observed in the intervention group in PPT, CPM, NRS, and FIQ. (4) Conclusions: A six-week telerehabilitation therapeutic exercise intervention consisting of two scheduled exercise sessions per week lasting approximately 45 min each is associated with reduced pain levels, enhanced pain inhibitory pathways, and a decreased impact of fibromyalgia compared to patients who do not adopt a more active lifestyle.…”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2003 by Denis E O’donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy D Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…Management strategies consisting of combined modern pharmacotherapy and nonpharmacotherapeutic interventions (eg, pulmonary rehabilitation/exercise training) can effectively improve symptoms, activity levels, and quality of life, even in patients with severe COPD. …”
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Histological Research and Phytochemical Characterization of <i>Capsella bursa-pastoris</i> Medik. from Bihor County, Romania by Sorina-Georgiana Onea (Minz), Annamaria Pallag, Cristina Burlou-Nagy (Fati), Tünde Jurca, Laura Gratiela Vicaș, Marian Eleonora, Neli Kinga Olah, Rita Kiss, Bianca Pașca

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