Pharmacologic Targets and Prototype Therapeutics in the Kallikrein-Kinin System: Bradykinin Receptor Agonists or Antagonists by J. N. Sharma, G.J. AL-Sherif

“…This system includes kininogen (precursor for kinin), kallikreins, and pharmacologically active bradykinin (BK), which is considered to be proinflammatory and/or cardioprotective. …”
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Pharmacological Evaluation of the SCID T Cell Transfer Model of Colitis: As a Model of Crohn's Disease by Thomas Lindebo Holm, Steen Seier Poulsen, Helle Markholst, Stine Reedtz-Runge

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Recurrent Obscure Gastrointestinal Bleeding: Dilemmas and Success with Pharmacological Therapies. Case Series and Review by Majid Almadi, Peter M Ghali, Andre Constantin, Jacques Galipeau, Andrew Szilagyi

“…The present article describes three difficult cases of recurrent bleeding from obscure causes, followed by a review of the pitfalls and pharmacological management of obscure gastrointestinal bleeding. …”
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Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation by Zhaohui Gong, Haixin Yang, Li Gao, Yi Liu, Qingmin Chu, Chuanjin Luo, Liang Kang, Huiqi Zhai, Qiang Xu, Wei Wu, Nan Li, Rong Li

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Exploration of the mechanism of luteolin against colorectal cancer based on network pharmacology and experimental validation by Wenjun Zhang, Fujie Zhang

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Chemical constituents, biological functions and pharmacological effects for comprehensive utilization of Eucommia ulmoides Oliver by Yi-Fan Xing, Dong He, Yi Wang, Wen Zeng, Chong Zhang, Yuan Lu, Nan Su, Yan-Hua Kong, Xin-Hui Xing

“…Keywords: Eucommia ulmoides Oliver, Comprehensive utilization, Chemical constituents, Biological functions, Pharmacological effects…”
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A Review of the Mechanism of Bailing for Diabetic Nephropathy Based on ChatGPT and Network Pharmacology by Weiwei Xi, Xuming Zhao, Boya Wang, Yichen Zhu, Hua Li

“…By employing network pharmacology, we delve into the possible pathways Bailing impacts DN treatment. …”
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Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

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Isolation and Identification of Endophytic Fungi from Syzygium cumini Linn and Investigation of Their Pharmacological Activities by Mst. Mabiya Sultana Samapti, Farhana Afroz, Satyajit Roy Rony, Suriya Sharmin, Fatema Moni, Shammi Akhter, Sheikh Feroz Uddin Ahmed, Md. Hossain Sohrab

“…This study was conducted to isolate and identify the endophytic fungi from the bark and leaves of the Syzygum cumini plant and investigate the pharmacological activities of endophytic fungi along with plant parts. …”
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Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review by Brijesh Singh Chauhan, Yash Pal Singh

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Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression by Lili Hu, Na Wu, Jue Wang, Donghui Cai

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The Influence of Pharmacological Preconditioning with Sevoflurane on Incidence of Early Allograft Dysfunction in Liver Transplant Recipients by Andrei F. Minou, Alexander M. Dzyadzko, Aliaksei E. Shcherba, Oleg O. Rummo

“…Background. Pharmacological preconditioning is one of the tools used to diminish preservation injury. …”
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Explication of Pharmacological Proficiency of Phytoconstituents from Adansonia digitata Bark: An In Vitro and In Silico Approaches by Sangavi P., Gowtham Kumar S., Nachammai KT., Chandrabose Selvaraj, Langeswaran K.

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Development of an mPBPK machine learning framework for early target pharmacology assessment of biotherapeutics by Krutika Patidar, Nikhil Pillai, Saroj Dhakal, Lindsay B. Avery, Panteleimon D. Mavroudis

Subjects: “…Target pharmacology, Antibodies, Pharmacokinetics, High-throughput ML, Decision tree classification.…”
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Pharmacological and Pharmacodynamic Implications of Nonsteroidal Anti-Inflammatory Drug Therapy in Elderly Arthritic Patients by W Watson Buchanan

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Using Bioinformatics Approach to Explore the Pharmacological Mechanisms of Multiple Ingredients in Shuang-Huang-Lian by Bai-xia Zhang, Jian Li, Hao Gu, Qiang Li, Qi Zhang, Tian-jiao Zhang, Yun Wang, Cheng-ke Cai

“…However, the in-depth research on targets and pharmacological mechanisms of SHL preparations was scarce. …”
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Study of Traditional Uses, Extraction Procedures, Phytochemical Constituents, and Pharmacological Properties of Tiliacora triandra by Gitishree Das, Sushanto Gouda, Rout George Kerry, Hernán Cortes, María L. Del Prado-Audelo, Gerardo Leyva-Gómez, Patrick Valere Tsouh Fokou, Erick P. Gutiérrez-Grijalva, J. Basilio Heredia, Han-Seung Shin, Jayanta Kumar Patra

“…Despite the plant species’ abundance of bioactive compounds, there is very little in vivo and clinical proof of its pharmacological significance. The present review focuses on the phytochemical configurations, extraction methods for major bioactive compounds, and pharmacology of T. triandra, in light of its potent medicinal values.…”
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Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics by Xiaomin Xu, Donghua Yu, Yu Wang, Xin Jiang, Fang Lu, Shumin Liu

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A review of the types of diets used in Crohn’s disease: the support system for pharmacological treatment by Joanna Śnieżna, Wojciech Wojciech Florczak, Jakub Dziewic, Karol Dzwonnik, Urszula Zelik, Gabriela Trestka, Wiktoria Domino, Kamila Stępień, Jagienka Włodyka, Sabina Adamczyk, Maria Przygoda

“…Its incidence is rising globally, particularly in industrializing regions, correlating with increased consumption of ultra-processed foods. Besides pharmacological and surgical treatment, the diet component plays a crucial role in alleviating symptoms of the disease and preventing its progression. …”
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Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

“…In cancer models that are genetically independent of CDK2, pharmacological inhibitors suppress cell proliferation by inducing 4N cell cycle arrest and increasing the expressions of phospho-CDK1 (Y15) and cyclin B1. …”
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