Effect of non-pharmacological interventions for overweight/obese women with polycystic ovary syndrome on ovulation and pregnancy outcomes: a protocol for a systematic review and network meta-analysis by Juan Li, Jie Yang, Fan-rong Liang, Jun Zhou, Gui-Xing Xu, Han Yang, Yan-qun Xiao, Jia-jia Liu, Zhi-yong Xiao, Xiao-yan Zheng, Li-ying Liu, Zheng Yu

“…However, effect and safety of these non-pharmacological interventions vary, and there is no standard method of clinical application. …”
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A systematic review of Randomized Controlled Trials about some non-pharmacological interventions for treatment of hypertension: Physical exercise, sodium restriction, weight and alcohol use reduction by Amobi Akonobi, Jawad Khan

“…Discussion and Conclusions: Our findings confirm that physical exercise, sodium restriction, weight and alcohol use reduction are four non-pharmacological interventions effective in the control of hypertension. …”
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Synergistic anticancer effects of cisplatin and phenolic aglycones of the aerial part of Rumex dentatus L. in tongue squamous cell carcinoma: insights from network pharmacology and biological verification by Amany E. Ragab, Ghada M. Al-Ashmawy, Sherin R. El Afify, Ola A. El-Feky, Amera O. Ibrahim

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Pharmacological modulation of Sigma-1 receptor ameliorates pathological neuroinflammation in rats with diabetic neuropathic pain via the AKT/GSK-3β/NF-κB pathway by Yuyu An, Shanshan Cao, Leilei Shi, Yuhan Zhang, Xin Wang, Shiyu Yuan, Yongheng Shi, Bin Wang, Jiping Liu, Chao-jun Han

“…The mRNA levels of TNF-α, IL-1β, and cyclooxygenase 2 (COX-2) were reduced. Pharmacological inhibition of Sig-1R with BD1047 (10 μM) abolished Sig-1R-mediated activation of lipopolysaccharide-treated BV-2 microglial cells. …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

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A review of Psoralea corylifolia L.: a valuable plant with profound biological significance by Anni Yang, Lingping Kong, Zhibo You, Xinyu Li, Jian Guan, Fengjin Li, Lingyun Zhong, Hai Jiang

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Polyporus umbellatus, A Precious Rare Fungus With Good Pharmaceutical and Food Value by Sizhu Ren, Hua Liu, Qing Sang, Yifan Sun, Liyan Li, Wenjie Chen

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Social network support for women with breast cancer undergoing chemotherapy by Diego Augusto Lopes Oliveira, Luiza Beatriz de França Silva, Sabrina Kelly Marinho Alves, Marilia Cruz Gouveia Camara Guerra, Vania Pinheiro Ramos

Subjects: “…social support; social network; breast neoplasms; pharmacological treatment…”
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Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers by Paulina Nadziakiewicz, Wioletta Szczurek-Wasilewicz, Bożena Szyguła-Jurkiewicz

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Innovative epilepsy management: a combined figure of EEG categorization and medication mechanisms by Mohamed Taha, Douglas R. Nordli, Carol Park, Douglas R. Nordli

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Asini Corii Colla (Ejiao) as a health-care food and traditional Chinese medicine: A review of its chemical composition, pharmacological activity, quality control, modern applications by Xiao-jun Yu, Ling-mei Kong, Bin Wang, Chang-qi Zhai, Yong-zhen Lao, Long-jian Zhang, Yan Gao, Bo-Nian Zhao

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HER-SAFE study design: an open-label, randomised controlled trial to investigate the safety of withdrawal of pharmacological treatment for recovered HER2-targeted therapy-related cardiac dysfunction by Robin Chung, James C Moon, Alexander R Lyon, Charlotte H Manisty, Muhummad Sohaib Nazir, Malcolm Walker, Peter Kellman, Benjamin Dowsing, Daniel Chen, Jessica Artico, Mark Westwood, Hakim-Moulay Dehbi, Rebecca Roylance, Tom Crake, Peter Schmid, Arjun Ghosh, Maria Sol Andres, Joanna Pedra, Orla Worn

“…The Randomised Controlled Trial for the Safety of Withdrawal of Pharmacological Treatment for Recovered HER2 Targeted Therapy Related Cardiac Dysfunction (HER-SAFE) aims to evaluate whether HFT can be safely withdrawn in non-high cardiovascular (CV) risk patients with ‘recovered’ HER2 CTRCD.Methods and analysis This is a multicentre, open-label randomised controlled trial investigating whether withdrawal of HFT is non-inferior to continuation in non-high CV risk, breast cancer survivors with recovered HER2 CTRCD after cancer treatment completion. …”
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Lingguizhugan decoction enhances autophagy of Alzheimer’s disease via regulating the mTOR/ p70s6K pathway in vivo and in vitro by Xiaojing Chen, Qingrong Tian, Min Gao, Xibin Zhou, Chunxiang Zhou

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Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis by Rong-Rong Wu, Duo-Rui Nie, Fang-Hui He, Zhi-Hang Li, Fei Xu, Fei Xu, Fei Xu

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Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease by Shuwen Qi, Chunzi Zhang, Junlin Yan, Xiaoyan Ma, Yewei Zhong, Wenhui Hou, Juan Zhang, Tuxia Pang, Xiaoli Ma

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Non-pharmacological Methods Used in the Management of Type 2 Diabetes Mellitus by a Selected Group of People with T2DM in Colombo District, Sri Lanka: A Mixed-Method Study by Lakshani Herath, Manisha Kamalsiri, Perananthan Inthuja, Gayani P Gamage, Dinithi Vidanage

“…The prevalence of T2DM in Sri Lanka is high due to the unhealthy lifestyles of individuals. Both pharmacological and non-pharmacological interventions are practiced by people with T2DM to achieve better glycemic control. …”
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Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases by Jialian Lv, Xinyue Song, Zixin Luo, Duoqin Huang, Li Xiao, Kang Zou

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Medicines for the management of overweight and obesity: A systematic review with network meta-analysis by Gabriela Masiero Marcon, Jhonatan Mendes Paiva, Mariana Delariva Sakiyama, Fernanda Stumpf Tonin, Fernando Fernandez-Llimos, Suzane Virtuoso, Andreia Cristina Conegero Sanches

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Therapeutic Approaches to Tackle the Challenge of Depression That Is Resistant to Treatment–A Narrative Review by Md. Rajdoula Rafe, Abdul Waris, Pranoy Saha

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The Efficacy of Fan Therapy to Alleviate Breathlessness among Lung Cancer Patients by Komang Noviantari

Subjects: “…dyspnea; non-pharmacological therapy; nursing intervention; oncology; respiratory disease.…”
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