Network analyses of brain tumor multiomic data reveal pharmacological opportunities to alter cell state transitions by Brandon Bumbaca, Jonah R. Huggins, Marc R. Birtwistle, James M. Gallo

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Method for determining of cytotoxicity based on the release of fluorescent proteins by Dmitry Lifanov, Dulamsuren Zorigt, Evgenya Shabalina, Abdullah Khalil, Konstantin Gorbunov, Elena Petersen

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Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways by Liang Zhu, Yanchi Bi, Ting Liang, Po Zhang, Xiao Xiao, Tengbo Yu

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Pimobendan oral solution is bioequivalent to pimobendan chewable tablets in beagle dogs by Olaf Kuhlmann, Michael Markert

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A Quantitative Examination and Comparison of the Ability of Australian Gentamicin Dosing Guidelines to Achieve Target Therapeutic Concentrations in Neonates by Luke E. Grzeskowiak, Sheree Wynne, Michael J. Stark

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Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents by Frank Mazza, Alexandre Guet-McCreight, Thomas D. Prevot, Taufik Valiante, Etienne Sibille, Etay Hay

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The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities by Lucinda Villaescusa Castillo, Francisco Zaragozá García, Cristina Zaragozá Arnáez

“…Specifically, comparative studies could be key to identifying species with unique chemical profiles and understanding how variations in secondary metabolite composition may influence their pharmacological activities. This work highlights the urgent need to expand research in these areas to validate the pharmacological properties of <i>Chiliadenus</i> species for their application in modern medicine.…”
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Patterns of pharmacological treatment in patients with atrial fibrillation: an analysis from the prospective GLORIA-AF Registry Phase III by Bernadette Corica, Giulio Francesco Romiti, Giuseppe Boriani, Brian Olshansky, Tze-Fan Chao, Menno V. Huisman, Marco Proietti, Gregory Y. H. Lip, on behalf of the GLORIA-AF Investigators

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Characterization of the Active Ingredient and Prediction of the Potential Mechanism of Dahuoluo Pill via Mass Spectrometry with the Network Pharmacology Method by Haoran Xu, Yuelin Bi, Xin Feng, Jiaqi Wang, Gengyuan Yu, Tonghua Zhang, Tianyi Li, Xuhua Gao, Runhua Liu, Yu Sun, Hao Wu, Linlin Fang, Chenning Zhang, Yikun Sun

“…We then used network pharmacology to predict the underlying mechanisms by which DHLP ameliorates rheumatoid arthritis. …”
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Neural mechanisms of non-pharmacological interventions in patients with mild cognitive impairment and Alzheimer's disease: An ALE meta-analysis by Ning Wang, Jinkun Li, Yunxiao Guo, Panbing Zhang, Fulin You, Ziyi Wang, Zhonghuan Wang, Xiaobin Hong

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Network pharmacology and molecular analysis of mechanisms underlying the therapeutic effects of Rhubarb in treating atherosclerosis and abdominal aortic aneurysm by Huilin Xu, Jun Huang, Youjie Zeng, Xia Wang, Huilin Lian, Siyi Zhang, Ren Guo

“…Aim of the study: The aim of this study was to systematically investigate the effects and mechanisms of Rhubarb in the treatment of Atherosclerosis (AS) and Abdominal Aortic Aneurysm (AAA) by utilizing network pharmacology and molecular docking techniques. Materials and methods: TCMSP systematic pharmacology database was utilized to search for active chemical components of Rhubarb. …”
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Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation by Lianling Xu, Lianling Xu, Kaixuan Zeng, Kaixuan Zeng, Zuoyue Duan, Zuoyue Duan, Jing Liu, Yan Zeng, Miao Zhang, You Yang, Qulian Guo, Yanling Jin, Wenjun Liu, Ling Guo

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Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma by Meng-Zhe Yang, Bei-Bei Zhang, Jian-Chun Huang, Xian-Yu Bai, Zhen-Qiang Liang, Xiang Yi, Ning Xu, Yuan-Jiao Huang, Ai-Jun Jiao

“…Taken together, this study revealed the potential drug targets and underlying mechanisms of polyphyllin II against NPC through modern network pharmacology, which provided a certain theoretical basis for the future nano TCM research.…”
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Pharmacological interventions for the management of anesthesia and sedation in patients with Duchenne muscular dystrophy: a systematic review and meta-analysis by Xianghong Lian, Xianghong Lian, Xianghong Lian, Yang Jing, Yang Jing, Yang Jing, Ting Luo, Ting Luo, Ting Luo, Yixin Guo, Yixin Guo, Yixin Guo, Yunzhu Lin, Yunzhu Lin, Yunzhu Lin

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Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model by I. P. Gileva, S. N. Yakubitskiy, I. V. Kolosova, S. N. Shchelkunov

“…Data obtained demonstrate that recombinant TNF-BD protein is pharmacologically active in the experimental model of LPS-induced septic shock.…”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant by Pritam Sarkar, Tasfiya Rufaidah Ahnaf, Razina Rouf, Jamil Ahmad Shilpi, Shaikh Jamal Uddin

“…Despite numerous studies demonstrating various pharmacological advantages of this plant and its constituents, the number of clinical trials conducted on humans remains significantly limited.…”
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Corrigendum to “Exploring comorbidity and pharmacological treatment patterns in psoriasis - A retrospective population-based cross-sectional study”

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Bioactive Molecules, Ethnomedicinal Uses, Toxicology, and Pharmacology of <i>Peltophorum africanum</i> Sond (Fabaceae): Systematic Review by Nkoana I. Mongalo, Maropeng V. Raletsena

“…The plant species possess very important pharmacological activities in vitro, which includes antimicrobial, anti-HIV, antioxidant, anticancer, antidiabetic, and other activities. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

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Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain by Peng Xi, Rui Mao, Shiyan Wu, Lei Liu, Ceng Cai, Lei Lu, Cailin Zhang, Yimei Li

“…Further, a rat model of VIN-induced neuropathic pain was established to confirm the reliability of the network pharmacology findings. Results. A total of 46 intersection targets were identified as potential therapeutic targets, mainly related to neuroinflammation. …”
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