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  1. 221

    Positive association between the proinsulin-to-C-peptide ratio and prolonged hyperglycemic time in type 2 diabetes by Aika Miya, Akinobu Nakamura, Hiroshi Nomoto, Hiraku Kameda, Tatsuya Atsumi

    Published 2024-04-01
    “…The proinsulin-to-C-peptide (PI:C) ratio is an index applied during the early stage of pancreatic β-cell dysfunction. …”
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    Article
  2. 222

    Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma by Haideh Namdari, Farhad Rezaei, Fatemeh Heidarnejad, Mohammad Yaghoubzad-Maleki, Maryam Karamigolbaghi

    Published 2024-01-01
    “…Computational assessments were performed on these chimeric vaccines for antigenicity, allergenicity, peptide toxicity, population coverage, and physicochemical properties. …”
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    Article
  3. 223
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    Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design by Muhammad Umar, Haroon Afzal, Asad Murtaza, Li-Ting Cheng

    Published 2025-01-01
    “…This lipidation is guided by bacterial signal peptides (SPs), which ensure the precise targeting and membrane anchoring of these proteins. …”
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    Article
  5. 225

    HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design by Amy L. Kessler, Roel F. A. Pieterman, Wouter A. S. Doff, Karel Bezstarosti, Rachid Bouzid, Kim Klarenaar, Diahann T. S. L. Jansen, Robbie J. Luijten, Jeroen A. A. Demmers, Sonja I. Buschow

    Published 2025-01-01
    “…Abstract Synthetic long peptides (SLPs) are a promising vaccine modality that exploit dendritic cells (DC) to treat chronic infections or cancer. …”
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    Article
  6. 226

    Estimation of calcitonin and calcitonin gene-related peptide-α in bone calcification in quail during laying period by Hadeel M. Hameed, Soulaf J. Kakel

    Published 2025-01-01
    “…The outcomes of the study indicate an elevation in the level of calcium and calcitonin during the peak and final period of egg production, followed by a rise in the quantity of gene-related peptide-α during the final period of egg laying, with a strong positive relationship between the level of phosphorus and calcium, as well as between gene-related peptide-α and calcitonin during the peak and final period of egg production. …”
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    Article
  7. 227

    Caveolin-1 Scaffolding Domain Peptide Regulates Colon Endothelial Cell Survival through JNK Pathway by Kai Fang, Christopher G. Kevil

    Published 2020-01-01
    “…AP-Cav significantly blunted VEGF-dependent extracellular signal-regulated kinase 1/2 (ERK 1/2) phosphorylation at 10 minutes and 2 hours after stimulation, compared with the AP control peptide. AP-Cav + VEGF-A treatment also significantly increased c-Jun N-terminal kinase (JNK) phosphorylation at 2 hours. …”
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    Article
  8. 228

    Hypercalcemia in Small Lymphocytic Lymphoma with an Elevated Parathyroid Hormone-Related Peptide Associated with Early Richter Transformation by Ashish Bains, Pedro Covas, Olga Timofeeva, Michael Bromberg

    Published 2021-01-01
    “…We report a case of small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) associated with hypercalcemia and an elevation in parathyroid hormone-related peptide (PTHrP) in the setting of a Richter transformation. …”
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    Article
  9. 229

    Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I by Bryan Neumann, Stephen McCarthy, Shane Gonen

    Published 2025-02-01
    “…One such inhibitor, the gating-modifier peptide Protoxin-I derived from tarantula venom, blocks channel opening by shifting the activation voltage threshold to more depolarized potentials, but the structural basis for this inhibition has not previously been determined. …”
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    Article
  10. 230

    Bioactive potential and storage behavior of low molecular mass peptides in Pilsner and IPA style craft beers by Roberta Nogueira Pereira da Silva, Angelica Priscila Parussolo Tonin, Gabriela Soares Macello Ramos, Juliana Furtado Dias, Eduardo Cesar Meurer, Maria Gabriela Bello Koblitz

    Published 2025-01-01
    “…Pilsner beers, typically clear due to added chill-proofing proteases, showed reduced peptide intensity over time, whereas IPA, which often remains hazy and lacks such enzymes, exhibited increased peptide levels. …”
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    Article
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    The ENaC taste receptor’s perceived mechanism of mushroom salty peptides revealed by molecular interaction analysis by Wen Li, Wanchao Chen, Di Wu, Zhong Zhang, Peng Liu, Zhengpeng Li, Yan Yang

    Published 2025-01-01
    “…The three subunits α, β, and γ of the ENaC taste receptor (SCNN1α, SCNN1β, and SCNN1γ) showed different recognition characteristics for the salty peptide. The salty peptide binding to the SCNN1α receptor was an entropy-driven reaction, while to SCNN1β and SCNN1γ was an enthalpy-driven reaction. …”
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  15. 235

    Inhibitory Effect of Curcumin-Cu(II) and Curcumin-Zn(II) Complexes on Amyloid-Beta Peptide Fibrillation by Rona Banerjee

    Published 2014-01-01
    “…The metal complexes also impart more improved inhibitory effects than Curcumin on peptide fibrillization.…”
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    Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? by Ortal Resnick, Fernando Bril, Fernando Bril, Giovanna Beauchamp

    Published 2025-01-01
    “…It discusses the evidence supporting the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) as potential adjunctive therapy in T1D to reduce weight and improve insulin resistance. …”
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    Comparison Of Glucagon Like Peptide/1 Levels In Diabetic Women With Ovarian Polycystic Syndrome And Healthy Women by Namra Iqtidar, Imran Ali Zaidi, Sobia Niaz, Javaria Latif, Amir Naveed, Ayesha Yousaf

    Published 2024-09-01
    “…A relatively novel peptide hormone which is included in incretins (Gut-derived hormones) is Glucagon-like peptide-1(GLP-1). …”
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    Article