Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis by Jerzy Chudek, Marta Pośpiech, Anna Chudek, Michał Holecki, Monika Puzianowska-Kuźnicka

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Research progress on the mechanism and markers of metabolic disorders in the occurrence and development of cognitive dysfunction after ischemic stroke by Huaqiang Li, Huaqiang Li, Xiaohua Ke, Bianying Feng, Huan Tian, Huan Tian, Zhenzhen Cai, Anren Zhang, Qiuhong Man

“…There is an urgent need to better understand the pathophysiology and pathogenesis of PSCI, as well as to identify markers that can predict PSCI early in the clinical stage, facilitating early prevention, monitoring, and treatment. …”
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When is synthetic sufficient? Ethical considerations and alternatives in simulation-based ultrasound education by Andrea J. Doyle, Claire M. Condron

“…Synthetic models offer key educational benefits over animal models by closely mimicking human anatomy and pathophysiology, providing consistent and anatomically accurate training. …”
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Daratumumab for autoimmune diseases: a systematic review by Martin Krusche, Ina Kötter, Lennard Ostendorf, Nikolas Ruffer, Marie-Therese Holzer, Tobias B. Huber

“…Usage of daratumumab in non-oncological or non-transplantation associated diseases with autoimmune pathophysiology was analysed including patient characteristics, therapeutic regimen, adverse events and patient outcome.Results 38 publications reporting the clinical course of 83 patients met the inclusion criteria. …”
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The Impact of C-Peptide and Diabetes Mellitus on Coronary Ectasia and Effect of Coronary Ectasia and C-Peptide on Long-Term Outcomes: A Retrospective Cohort Study by Kenan Toprak, Mustafa Kaplangoray, Ali Palice

“…Although it has common risk factors with atherosclerotic CAD in its development, the pathophysiology of CAE is not fully known and it is not seen in every CAD suggesting that different determinants may play a pivotal role in the development of CAD. …”
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Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation by Ryo Miyake, Kisho Ohtani, Toru Hashimoto, Ryoko Yada, Tasuku Sato, Yoko Shojima, Shunji Hayashidani, Taiki Higo, Hiroyuki Tsutsui

“…Catecholamine‐induced cardiac injury or vasospasm has been implicated in this pathophysiology. We present a case of a 67‐year‐old man 10 years after heart transplantation diagnosed with TTS. …”
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The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia by Ping Chen, Min Wang, Daqi Li, Yan Jia, Na He, Wei Li, Daoxin Ma, Chunyan Ji

“…In the present study, we mainly investigated the role of Th22, Th17, and Th1 cell and their related cytokines (IL-22, IL-17, and IFN-r) in the pathophysiology of CML. Bone marrow (BM) and peripheral blood (PB) were extracted from newly diagnosed (ND), chronic phase- (CP-) CML patients, and controls. …”
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Meta-Analysis of Visual Evoked Potential and Parkinson’s Disease by Song-bin He, Chun-yan Liu, Lin-di Chen, Zhi-nan Ye, Ya-ping Zhang, Wei-guo Tang, Bin-da Wang, Xiang Gao

“…Our findings suggest that electrophysiological changes and functional defect in the visual pathway of PD patients are important to our understanding of the pathophysiology of visual involvement in PD.…”
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Performance of current tools used for on-the-day assessment and diagnosis of mild traumatic brain injury in sport: a systematic review by Phoebe Haste, Leonardo de Almeida e Bueno, Antoine Jérusalem, Jeroen Bergmann

“…Further exploration of the mechanisms and time-dependent pathophysiology of SR-mTBI could result in more targeted diagnostic and monitoring techniques. …”
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Schizophrenia recognition based on three-dimensional adaptive graph convolutional neural network by Guimei Yin, Jie Yuan, Yanjun Chen, Guangxing Guo, Dongli Shi, Lin Wang, Zilong Zhao, Yanli Zhao, Manjie Zhang, Yuan Dong, Bin Wang, Shuping Tan

“…Abstract Previous deep learning-based brain network research has made significant progress in understanding the pathophysiology of schizophrenia. However, it ignores the three-dimensional spatial characteristics of EEG signals and cannot dynamically learn the interactions between nodes. …”
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A review on mechanisms of action of bioactive peptides against glucose intolerance and insulin resistance by Forough Jahandideh, Jianping Wu

“…Insulin resistance plays a key role in the pathophysiology of type 2 diabetes and metabolic syndrome. …”
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Selected Parameters of Nutritional and Pro-Health Value in the Common Carp (Cyprinus carpio L.) Muscle Tissue by J. Kłobukowski, K. Skibniewska, K. Janowicz, F. Kłobukowski, E. Siemianowska, E. Terech-Majewska, J. Szarek

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Two Cases of Severe Hypertension in JAK2 Mutation-Positive Myeloproliferative Neoplasms by Raunak Rao, Spoorthy Kulkarni, Ian B. Wilkinson

“…Hyperviscosity and constitutive JAK-STAT activation are amongst the proposed pathophysiology linking myeloproliferative neoplasms and hypertension. …”
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IL-18 biology in severe asthma by Sarita Thawanaphong, Sarita Thawanaphong, Sarita Thawanaphong, Aswathi Nair, Aswathi Nair, Emily Volfson, Emily Volfson, Parameswaran Nair, Parameswaran Nair, Manali Mukherjee, Manali Mukherjee

“…We explore the multifaceted role of IL-18 in asthma pathophysiology, including its interactions with other cytokines and contributions to both T2 and non-T2 inflammation. …”
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Artery of Percheron Infarction as an Unusual Cause of Korsakoff’s Syndrome by Yongxing Zhou, Derrick Fox, Abhishek Anand, Amal Elhaj, Arushi Kapoor, Faranak Najibi, Han Kim, Roger Weir, Annapurni Jayam-Trouth

“…Although the exact pathophysiology is unknown, various studies have identified brain lesions in the thalami, mammillary bodies, and frontal cortex. …”
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Mechanisms of Herbal Nephroprotection in diabetes mellitus by Dorin Dragoș, Maria Mirabela Manea, Delia Timofte, Dorin Ionescu

“…Phytoceuticals offer a promising alternative as they act on the many-sidedness of DN pathophysiology, multitargeting its intricacies. This paper offers a review of the mechanisms underlying the protective action of these phytoagents, including boosting the antioxidant capabilities, suppression of inflammation, averting the proliferative and sclerosing/fibrosing events. …”
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A volumetric study of the choroid plexus in neuropsychiatric systemic lupus erythematosus by Hu Liu, Huiyang Liu, Huanhuan Li, Bailing Tian, Zhen Sun, Wen Xiong, Zhenxing Li, Pingting Yang, Guoguang Fan

“…Abstract Much evidence suggests that the choroid plexus (CP) plays an important role in the pathophysiology of systemic lupus erythematosus (SLE), but its imaging profile in neuropsychiatric SLE (NPSLE) remains unexplored. …”
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Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery by Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius

“…To build on these findings, and to identify potential biomarkers that can be related to pathophysiology, we measured differences in protein expression in platelet-poor plasma (PPP) samples from 15 ME/CFS study participants and 10 controls not previously infected with SARS-CoV-2, using DIA LC-MS/MS. …”
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Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls by Christian N. Schmitz, Gebhard Sammer, Elena Neumann, Carlo Blecker, Gerhard Gründer, Hana Adolphi, Eva Kathrin Lamadé, Bruno Pedraz-Petrozzi

“…Abstract Inflammatory processes have been implicated in the pathophysiology of depression. In human studies, inflammation has been shown to act as a critical disease modifier, promoting susceptibility to depression and modulating specific endophenotypes of depression. …”
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Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema by Eleni Dimitriou, Theodoros N. Sergentanis, Vaia Lambadiari, George Theodossiadis, Panagiotis Theodossiadis, Irini Chatziralli

“…These findings may shed light on the pathophysiology of DME and its correlation with the development of specific clinical signs.…”
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