The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis by Shayan Mardi, Maryam Rashidian, Fatemeh Bastan, Ghazale Molaverdi, Sayed-Hamidreza Mozhgani

“…Despite extensive research, the exact pathophysiology of HTLV infection and its related diseases is enigmatic. …”
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Coronary Artery Spasm: New Insights by Anthony Matta, Frederic Bouisset, Thibault Lhermusier, Fran Campelo-Parada, Meyer Elbaz, Didier Carrié, Jerome Roncalli

“…A wide spectrum of clinical manifestations from silent disease to sudden cardiac death was attributed to this complex entity with unclear pathophysiology. Multiple mechanisms such as the autonomic nervous system, endothelial dysfunction, chronic inflammation, oxidative stress, and smooth muscle hypercontractility are involved. …”
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Identifying Key Biomarkers and Immune Infiltration in Female Patients with Ischemic Stroke Based on Weighted Gene Co-Expression Network Analysis by Haipeng Xu, Kelin He, Rong Hu, YanZhi Ge, Xinyun Li, Fengjia Ni, Bei Que, Yi Chen, Ruijie Ma

“…The immune system may play an important role in the pathophysiology of females with IS. Therefore, it is critical to investigate the key biomarkers and immune infiltration of female IS patients to develop effective treatment methods. …”
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The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (H... by Darshan Hullon, Ghasaq K. Subeh, Yelizaveta Volkova, Karolina Janiec, Adam Trach, Ruslan Mnevets

“…Endothelial dysfunction is a significant component of HFpEF pathophysiology, and glucagon-like peptide-1 receptor (GLP-1R) agonists have shown potential benefits in improving endothelial function. …”
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Carotid Baroreceptor Stimulation for the Treatment of Resistant Hypertension by Vasilios Papademetriou, Michael Doumas, Charles Faselis, Constantinos Tsioufis, Stella Douma, Eugene Gkaliagkousi, Chrysanthos Zamboulis

“…It is only recently that the profound understanding of the complex anatomy and pathophysiology of the circuit, combined with the accumulation of relevant experimental and clinical data both in animals and in humans, has allowed the development of a more effective and well-promising approach. …”
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Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury by Shataakshi Dube, Tejasvi Matam, Jessica Yen, Henry E. Mang, Pierre C. Dagher, Takashi Hato, Timothy A. Sutton

“…Consequently, we used a mouse with a genetic deletion of Stat3 restricted to the endothelium to examine the role of STAT3 signaling in the pathophysiology of ischemic AKI. In a mouse model of ischemic AKI, the loss of endothelial STAT3 signaling significantly exacerbated kidney dysfunction, morphologic injury, and proximal tubular oxidative stress. …”
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Central amygdala neuroimmune signaling in alcohol use disorder by Mariam Melkumyan, Patrick A. Randall, Yuval Silberman

“…This review delves into how chronic alcohol exposure affects neuroimmune signaling in the CeA, contributing to the pathophysiology of AUD. By focusing on the impact of cytokine expression and glial cell activation, this review aims to elucidate the mechanisms by which neuroinflammation in the CeA influences alcohol-related behaviors. …”
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Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders by Tim Takken, Wim G. Groen, Erik H. Hulzebos, Cornelia G. Ernsting, Peter M. van Hasselt, Berthil H. Prinsen, Paul J. Helders, Gepke Visser

“…Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.…”
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Decoding the mechanisms behind second primary cancers by Meiyuan Zeng, Anqi Lin, Aimin Jiang, Zhengang Qiu, Hongman Zhang, Shifu Chen, Mingyan Xu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo

“…This comprehensive analysis contributes to elucidating current research trends in SPC mechanisms and enhances our understanding of the underlying pathophysiology. Furthermore, potential applications of intratumoral microbes, single-cell multi-omics, and metabolomics in investigating SPC mechanisms are also discussed, providing new ideas for follow-up studies.…”
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Immunocytochemical and Morphometric Studies of Gastrin-, Somatostatin- and Serotonin-Producing Cells in the Stomach and Duodenum of Patients with Acid Peptic Disorders by WR Yacoub, ABR Thomson, P Hooper, LD Jewell

“…These results suggest that a change in the number of G, D or EC cells does not play a primary role in the pathophysiology of acid peptic disorders in the majority of patients.…”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia by Anna Picca, Francesca Fanelli, Riccardo Calvani, Giuseppina Mulè, Vito Pesce, Alex Sisto, Cecilia Pantanelli, Roberto Bernabei, Francesco Landi, Emanuele Marzetti

“…Although muscle aging has been increasingly recognized as a biomarker of aging, the pathophysiology of sarcopenia is to date only partially appreciated. …”
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Placental Growth Factor, Soluble fms-Like Tyrosine Kinase 1, Soluble Endoglin, IL-6, and IL-16 as Biomarkers in Preeclampsia by Carmen Rădulescu, Anca Bacârea, Adina Huțanu, Rozalia Gabor, Minodora Dobreanu

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Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population by Anna Machalińska, Aleksandra Zakrzewska, Krzysztof Safranow, Barbara Wiszniewska, Bogusław Machaliński

“…Our findings extend current knowledge on the pathophysiology of MGL.…”
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Recent advances in near-infrared photobiomodulation for the intervention of acquired brain injury by Yujing Huang, Yujing Zhang, Chen Yang, Mengze Xu, Zhen Yuan

“…In this review, we first inspected the possible physical and biological mechanisms of NIR-PBM, and then reported the pathophysiology and physiology of ABI underlying NIR-PBM intervention. …”
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Treatment of tardive dyskinesia caused by long-term antipsychotic use: case reports and literature review by I. Pabarčiūtė, M. Karnickas

“…In order to provide reliable evidence-based recommendations for the treatment of tardive dyskinesia and to better understand its pathophysiology, genetic predisposition, and therapeutic agents, more studies with larger samples and more uniform conditions are needed. …”
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The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer: A Model System within Bone Marrow by Bobby Y. Reddy, Philip K. Lim, Kimberly Silverio, Shyam A. Patel, Brian Wong Won, Pranela Rameshwar

“…The uncovered significance of the microenvironment in the pathophysiology of breast cancer metastasis has served to challenge previously widespread theories and introduce new perspectives for the future research to eradicate breast cancer. …”
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Role of HO/CO in the Control of Peripheral Circulation in Humans by David Sacerdoti, Despina Mania, Paola Pesce, Silvia Gaiani, Angelo Gatta, Massimo Bolognesi

“…Experimental studies show that the heme oxygenase/carbon monoxide system (HO/CO) plays an important role in the homeostasis of circulation and in the pathophysiology of hypertension. No data are available on its role in the control of peripheral circulation in humans. …”
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Intrauterine Fetal Surgery Current Approaches by Ayla Eser, Nermin Köşüş, Aydın Köşüş, Müberra Namlı Kalem, Nilüfer Akgün, Ebru Yüce

“…It is mainly indicated in diseases that can result in intrauterine fetal death or whose effects could not be corrected postnatally (congenital aortic valve stenosis, hypoplastic left heart syndrome ect.). The proven pathophysiology and proper identification of the defect or disease is thus necessary before attempting such intervention. …”
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Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells by Alicia M. Thorne, Twila A. Jackson, Van C. Willis, Andrew P. Bradford

“…However, molecular mechanisms and signaling pathways underlying their etiology and pathophysiology remain poorly understood. We have shown that protein kinase Cα (PKCα) is aberrantly expressed in endometrioid tumors and is an important mediator of endometrial cancer cell survival, proliferation, and invasion. …”
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Toll-Like Receptor-4 Mediated Inflammation Is Involved in the Cardiometabolic Alterations Induced by Intermittent Hypoxia by Laureline Poulain, Vincent Richard, Patrick Lévy, Maurice Dematteis, Claire Arnaud

“…Intermittent hypoxia (IH) is a major component of sleep apnea syndrome as its cardiometabolic complications have been mainly attributed to IH. The pathophysiology is still poorly understood but there are some similarities with the obesity-associated cardiometabolic complications. …”
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