The Optimal Timing of Platelet-Rich Plasma (PRP) Injection for Nerve Lesion Recovery: A Preliminary Study by Muhammad Pandunugrahadi, Komang Agung Irianto, Oen Sindrawati

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Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics by Ibrahim El-Serafi, Sinclair Steele

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Developmental defects in ectodermal appendages caused by missense mutation in edaradd gene in the nfr mangrove killifish kryptolebias marmoratus by Hussein A. Saud, Paul A. O’Neill, Brian C. Ring, Tetsuhiro Kudoh

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Hormonal Implications of SARS-CoV-2: A Review of Endocrine Disruptions by Aliya Yskak, Yevgeniy Sokharev, Kuanysh Zhumalynov, Elizaveta Koneva, Natalia Afanasyeva, Dmitri Borodulin, Dmitrii Babaskin, Almabek Nugmanov, Murat Nurushev, Vadim Chashkov

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Incidence and Implications of Culture-Positive Corneoscleral Rims in Corneal Transplantation by Meeraalam Z, Alreshidi SO, ALBalawi HB, Alali NM, Hashem F, Kirat OM

“…Zuheer Meeraalam,1 Shaker O Alreshidi,2 Hani B ALBalawi,3 Naif M Alali,3 Faris Hashem,3 Omar M Kirat4 1Ophthalmology Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia; 2Ophthalmology Division, Department of Surgical Specialties, College of Medicine, Majmaah University, Majmaah, Saudi Arabia; 3Division of Ophthalmology, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia; 4Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaCorrespondence: Hani B ALBalawi, Division of Ophthalmology, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, 71491, Saudi Arabia, Email hb.albalawi@ut.edu.saBackground: Corneal transplantation is a critical procedure for restoring vision affected by different corneal pathologies. However, postoperative infections threaten graft survival, particularly microbial keratitis and endophthalmitis.Objective: This study aims to evaluate the incidence of culture-positive corneoscleral rims (CPCR) among transplanted corneas at a tertiary eye hospital and explore its association with death-preservation and preservation-surgery times.Methods: A retrospective analysis of keratoplasty surgeries performed in 2015 was conducted, involving 603 cases meeting the study criteria.Results: The incidence of CPCR was found to be 4.6%, predominantly bacterial (68%), with Methicillin-resistant Staphylococcus epidermidis (MRSE) being the most common isolate, followed by fungal (32%) species, notably Candida. …”
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From Molecule to Patient Rehabilitation: The Impact of Transcranial Direct Current Stimulation and Magnetic Stimulation on Stroke—A Narrative Review by Anca Badoiu, Smaranda Ioana Mitran, Bogdan Catalin, Tudor Adrian Balseanu, Aurel Popa-Wagner, Florin Liviu Gherghina, Carmen Valeria Albu, Raluca Elena Sandu

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Physical Therapists Use of Diagnostic Ultrasound Imaging in Clinical Practice: A Review of Case Reports by Robert Manske, Katherine Podoll, Alycia Markowski, Maureen Watkins, Lorna Hayward, Murray Maitland

“…The most common indication for USI was a differential diagnosis list that included serious pathologies. Case studies often had more than one indication. …”
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Can Primary Cardiac Myxofibrosarcoma Grow Quickly from Zero to a Size Leading to Left-Sided Heart Failure within 9 Months? by Levan Karazanishvili, Eduard Limonjiani

“…The tumor was completely excised, and the excision point was strengthened with a running suture. The following pathologic diagnosis was finally made: myxofibrosarcoma, FNCLCC (National Federation of Cancer Centres) Grade 2. …”
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3D ophthalmic ultrasonography at the slit lamp using existing ultrasound systems. by Jack O Thomas, Josiah K To, Parsa Riazi Esfahani, Frithjof Kruggel, William C Tang, Andrew W Browne

“…In vivo imaging revealed the system's capability to produce high-resolution 3D reconstructions of ocular structures, including eyes with pathological conditions.<h4>Conclusions</h4>The introduction of a slit lamp-mounted 3DUS system represents a significant advancement in ophthalmic ultrasonography, offering a practical and accessible solution for comprehensive 3D ocular assessments. …”
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Ultrastructural changes in the common carotid artery in terms of age and gender-related in Rat model by Nejat Ünlükal

“…A condition like atherosclerosis or thrombosis in the circulatory system results in permanent harm to structures like the central nervous system, heart and even fatality. Although the pathologies observed in the vessels are commonly attributed to the generation of atheromas, it has been recognised in recent years that changes in the tunica intima and tunica media lead to impaired vascular function without the formation of atheromas. …”
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The clinical value of computed tomography Hounsfield unit for diagnosing palpable inguinal lymph node metastasis in patients with penile cancer by Yu Li, Yu Chen, Gansheng Xie, Gang Li, Huming Yin

“…BackgroundComputed tomography (CT) Hounsfield units (HUs) of pathologically confirmed metastatic inguinal lymph nodes (ILNs) were proved to be higher than negative ones. …”
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Sustained Impairment in Cardiopulmonary Exercise Capacity Testing in Patients after COVID-19: A Single Center Experience by Georg Evers, Arik Bernard Schulze, Irina Osiaevi, Kimon Harmening, Richard Vollenberg, Rainer Wiewrodt, Rudin Pistulli, Matthias Boentert, Phil-Robin Tepasse, Juergen R. Sindermann, Ali Yilmaz, Michael Mohr

“…To objectify the reduced EC after COVID-19 and to evaluate for pathologic limitations. Methods. Thirty patients with subjective limitation of EC performed cardiopulmonary exercise testing (CPET). …”
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Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cas... by Haitao Lu, Qianqian Xu, Guming Zou, Hongmei Gao, Yue Yang, Wenge Li, Li Zhuo

“…Immunopathologic characteristics of HBV-MN patients and anti-PLA2R antibody positivity were analyzed.Results Among 420 pathologically confirmed HBV-MN patients, 230 (54.8%) were seropositive for HBV. …”
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Xiaoyao Pills Attenuate Inflammation and Nerve Injury Induced by Lipopolysaccharide in Hippocampal Neurons In Vitro by Yang Fang, Boyu Shi, Xiaobo Liu, Jie Luo, Zhili Rao, Rong Liu, Nan Zeng

“…Our study shows that lipopolysaccharides induce inflammation and nerve damage in hippocampal neurons, which are closely related to the pathological mechanism of depression. Xiaoyao Pills (XYW) play an important neuroprotective effect, which is related to its inhibition of neuronal inflammation and promoting the recovery of nerve injury. …”
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Dulaglutide Protects Mice against Diabetic Sarcopenia-Mediated Muscle Injury by Inhibiting Inflammation and Regulating the Differentiation of Myoblasts by Fengyi Deng, Wenyan Wu, Xingyu Fan, Xing Zhong, Nuojin Wang, Yue Wang, Tianrong Pan, Yijun Du

“…Mouse muscle tissues were then pathologically evaluated and stained with F4/80 or MPO to detect macrophages and neutrophils, respectively. …”
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Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future Outcomes by Radu Crisan-Dabija, Cristina Grigorescu, Cristina-Alice Pavel, Bogdan Artene, Iolanda Valentina Popa, Andrei Cernomaz, Alexandru Burlacu

“…Second, although challenging due to data scarcity, investigating the pathological pathways linking TB and SARS-CoV-2 leads to the idea that their coexistence might yield a more severe clinical evolution. …”
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Link between bilaterality and type 2 inflammation in respiratory epithelial adenomatoid hamartomas: A two-center retrospective cohort study. by Yujin Heo, Sang Duk Hong, Hyo Yeol Kim, Gwanghui Ryu, Kyung Won Kwon, Yong Gi Jung

“…<h4>Methods</h4>This retrospective analysis included patients with REAH who underwent endoscopic surgery and received pathological confirmation between November 2008 and November 2023. …”
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Transient ocular hypertension remodels astrocytes through S100B. by Weiran Huang, Kenji Matsushita, Rumi Kawashima, Susumu Hara, Yuichi Yasukura, Kaito Yamaguchi, Shinichi Usui, Koichi Baba, Andrew J Quantock, Kohji Nishida

“…A mouse model of transient ocular hypertension (OHT) and an in vitro cell stretch model were established to mimic the pathological conditions of increased intraocular pressure and mechanical stress on cultured cells. …”
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Metabolism features and milk microbiota of cows with mastitis in the Amur Oblast by M. E. Ostyakova, I. S. Shulga, V. K. Irkhina, K. S. Kositsyna, N. S. Golaydo

“…Water and mineral metabolism disorders were confirmed by low levels of calcium (1.80 ± 0.03 mmol/L) and magnesium (0.70 ± 0.02 mmol/L), which is a sign of many pathological conditions, and is associated with heavy lactation. …”
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Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects by Sogand Zareisedehizadeh, Fu-Xun Heng, Chay-Hoon Tan, Paul Chi-Lui Ho, Hwee-Ling Koh

“…Leea indica demonstrated remarkable antiplatelet and anticoagulant activities, highlighting its potential in preventing pathological thrombus formation and related cardiovascular disorders.…”
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