How to teach the anatomy of the inguinal canal? A multimodal approach by Shina Yeo Qing Chun, Nathaniel Dexter Salim, Lai YuFu Jarrell, Joshua Koh Zhi Yuan, Eng-Tat Ang, Davide Lomanto

“…However, the usefulness of modelling in learning the anatomy and pathologies of inguinal canal was insignificant. Our research design was inadequate in showing long term gain. …”
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Agrobiodiversity as a Reservoir of Medicinal Resources: Ethnobotanical Insights from Aymara Communities in the Bolivian Andean Altiplano by Simón Cocarico, Diego Rivera, Stephan Beck, Concepción Obón

“…In total, we recorded 1477 use reports addressing 260 pathologies across 28 major health categories. Notably, cultivated plants and weeds represent 38.8% of the medicinal species, highlighting their essential role in local healthcare practices. …”
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Are Exercise Therapy Protocols For The Treatment of Hip-Related Pain Adequately Described? A Systematic Review of Intervention Descriptions by August Estberger, Joanne L Kemp, Kristian Thorborg, Anders Pålsson, Eva Ageberg

“…# Background Hip-related pain is an umbrella term encompassing pain from non-arthritic hip joint pathologies, such as femoroacetabular impingement syndrome, hip dysplasia, and labral tears. …”
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Titin fragment is a sensitive biomarker in Duchenne muscular dystrophy model mice carrying full-length human dystrophin gene on human artificial chromosome by Yosuke Hiramuki, Miwa Hosokawa, Kayo Osawa, Taku Shirakawa, Yasuhiro Watanabe, Ritsuko Hanajima, Hiroyuki Kugoh, Hiroyuki Awano, Masafumi Matsuo, Yasuhiro Kazuki

“…The human dystrophin derived from DYS-HAC1 improved pathological phenotypes observed in DMD-null mice, which lack the entire 2.4 Mb of the dystrophin gene. …”
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Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation by Guangtang Chen, Xueping Shi, Rukai Jiao, Jiacai Qian, Xiaolin Du, Jian Liu, Xi Zeng

“…Methods This study comprehensively analyzed several mainstream bioinformatics databases to explore the expression, diagnostic efficacy, clinical pathological features, immune infiltration, prognostic value, and biological functions of NCOA4 in LGG. …”
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The Effect of Continuity of Midwifery Care (CoMC) Based on EDUGARLIN Application and Booklet on Postpartum Fitness Quality by Junengsih Junengsih, Rosita Syarifah, Ani Kusumastuti, Herlyssa Herlyssa, Elly Dwi Wahyuni, Yulia Ulfah Fatimah, Lia Nurcahyani, Fahmi Hafid

“…Several studies have shown that the discomfort experienced can lead to pathological development and complications when not treated properly. …”
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Pattern of Thrombocytopenia In Pregnancy At Teaching Hospital Of Rahim Yar Khan, Pakistan by Muhammad Bilal Ghafoor, Faiza Sarwar, Tahira Afzal Durrani, Zainab Quratulain Azher, Saleha Jabeen, Muhammad Haris Ali Khan

“…Although pregnancy is related with physiological variations in platelet count, however, several pathological conditions also cause thrombocytopenia showing significant impact on health of mother and her baby. …”
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Abatement by Alhagi maurorum of lead-induced nephrotoxicity in rats: emphasis on Nrf2/HO-1 by Mardi M. Algandaby

“…However, AM o-treatment ameliorated such pathological changes. In addition, AM treatment prevented Pb-induced accumulation of malondialdehyde (MDA), attenuated glutathione (GSH) depletion, and catalase (CAT) and superoxide dismutase (SOD) exhaustion. …”
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Biliary Atresia Treatment: Can Shear Wave Elastography Predict Kasai Procedure Outcomes? by Sekarsari Damayanti, Gema Ramadhan Muhammad, Rinaldhy Kshetra, Prihartono Joedo

“…Objective Biliary atresia is a significant cause of neonatal pathological jaundice, demanding effective interventions such as the Kasai procedure to impede its advancement. …”
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Synergistic toxicity of nanoplastics and Helicobacter pylori on digestive system in mice by Xiaolin Zhang, Yunqing Wang, Xiaohan Tong, Boqing Li, Sisi Liu, Yingzi Cui, Wenke Wang, Zhiqin Li, Chunlei Ma, Ying Zhang

“…Transmission electron microscopy confirmed the accumulation of AuPS-NPs (Au-core polystyrene nanoplastics) in the stomach, colon, and liver, while hematoxylin and eosin staining revealed dose-dependent pathological damage in these tissues. Enzyme-linked immunosorbent assays quantified interleukin-6 (IL-6), malondialdehyde (MDA), triglyceride (TG), and lactate dehydrogenase (LDH) levels, which significantly increased in co-exposure groups compared to single-exposure groups (P < 0.05). …”
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Parent-of-origin effects on nuclear chromatin organization and behavior in a Drosophila model for Williams–Beuren Syndrome by A. V. Medvedeva, E. V. Tokmatcheva, A. N. Kaminskaya, S. A. Vasileva, E. A. Nikitina, A. V. Zhuravlev, G. A. Zakharov, O. G. Zatsepina, E. V. Savvateeva-Popova

“…Simple experimental model systems such as Drosophila help probe the causes and consequences leading to human neurocognitive pathologies. Recently, we have developed a Drosophila model for Williams–Beuren Syndrome (WBS): a mutant agnts3 of the agnostic locus (X:11AB) harboring the dlimk1 gene. …”
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Defining New Research Questions and Protocols in the Field of Traumatic Brain Injury through Public Engagement: Preliminary Results and Review of the Literature by Shumaila Hasan, Aswin Chari, Mario Ganau, Chris Uff

“…Brain tissue sampling is the mainstay of diagnosis in neuro-oncology; following on this path, we hypothesise that information gleaned from neural tissue samples obtained in TBI patients upon hospital admission may correlate with outcome data in TBI patients, enabling an early, accurate, and more comprehensive pathological classification, with the intent of guiding treatment and future research. …”
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Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer by Zixuan Xue, Ye Yan, Huiying Chen, Hai Mao, Tianwu Ma, Guoliang Wang, Hongxian Zhang, Lulin Ma, Jianfei Ye, Kai Hong, Fan Zhang, Shudong Zhang

“…Patients were categorized into lymphatic leakage(n = 254)and non-leakage groups (n = 280) and compared demographic, perioperativ and pathologic factors. Multivariate logistic regression was applied to identify risk factors for lymphatic leakage. …”
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Comparative survival outcomes of neoadjuvant and adjuvant therapy in patients with T1c, node-negative, triple-negative breast cancer: A population-based analysis by Yi-Zi Zheng, Jia-Qi Ying, Ting-Ting Wu, Yong-Hui Su, Ou-Chen Wang

“…The multivariate Cox model showed that not achieving pathological complete response (non-pCR) following NAT, compared to AT, was associated with considerably worse OS (hazard ratio [HR], 2.207; 95 % confident intervaI [CI], 1.431–3.405; p < 0.001) and worse BCSS (HR, 2.184; 95 % CI, 1.348–3.537; p = 0.002). …”
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A case report: interstitial pneumonia following treatment of gastric cancer with sintilimab in combination with S-1 by Pei Zhu, Qingming Sun, Sheng Xu, Wanhui Dong

“…BackgroundInterstitial pneumonia is a group of pathologies affecting the pulmonary interstitium, characterized by interstitial fibrosis and extensive alveolar consolidation. …”
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The Prevalence of Metabolic Syndrome and Hypertriglyceridemic Waist Based on Sociodemographic Variables and Healthy Habits in Healthcare Workers: A Retrospective Study by Pedro Javier Tárraga Marcos, Ángel Arturo López-González, Emilio Martínez-Almoyna Rifá, Hernán Paublini Oliveira, Cristina Martorell Sánchez, Pedro Juan Tárraga López, José Ignacio Ramírez-Manent

“…<b>Introduction</b>: Metabolic syndrome (MetS) and hypertriglyceridemic waist (HTW) are two multifactorial pathological conditions that have been increasing in prevalence worldwide. …”
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Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury by Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang

“…Acute kidney injury (AKI) is associated with a high mortality rate. Pathologically, renal ischemia/reperfusion injury (RIRI) is one of the primary causes of AKI, and hypoxia-inducible factor (HIF)-1α may play a defensive role in RIRI. …”
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Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway by Yingli Xuan, Ting-ting Ding, Xiao-lei Mao, Shiqing Pang, Ruibin He, Li Qin, Jiang zi Yuan

“…Besides, hematoxylin–eosin staining and periodic acid-Schiff staining were used to observe the pathological changes of kidney tissue; immunohistochemistry, western blot, and real-time quantitative PCR to assess the calmodulin-dependent protein kinase kinase beta (CaMKKβ)/AMPK signaling pathway activation.Results Liraglutide significantly reduced serum lipid loading, improved kidney function, and relieved kidney histopathological damage and glycogen deposition in the mouse model of obesity-related kidney disease induced by HFD. …”
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Fully automated segmentation and classification of renal tumors on CT scans via machine learning by Jang Hee Han, Byung Woo Kim, Taek Min Kim, Ji Yeon Ko, Seung Jae Choi, Minho Kang, Sang Youn Kim, Jeong Yeon Cho, Ja Hyeon Ku, Cheol Kwak, Young-Gon Kim, Chang Wook Jeong

“…Materials and methods The model was developed using computed tomography (CT) images of pathologically proven renal tumors collected from a prospective cohort at a medical center between March 2016 and December 2020. …”
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Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…Phytochemicals derived from many medicinal plants have shown potent outcomes in protection against various pathological conditions including interstitial cystitis. …”
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