Intravascular Papillary Endothelial Hyperplasia of Buccal Mucosa Masquerading as Mucocele - A Case Report by Deepak Pandiar, Reshma Poothakulath Krishnan, Aklesha Behera, Pratibha Ramani

“…Discussion: The case is supported by a plausible mechanism involved in the pathogenesis. Thus, IPEH must be included in the clinical differential diagnosis of oral mucoceles and hemangioma. …”
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The rhabdoid variant of adrenocortical carcinoma-Report of three cases and literature review by Pavithra Ayyanar, Mukund N. Sable, Amit K. Adhya, Manoj K. Das, Madhabananda Kar, Pritinanda Mishra

“…Identifying more cases of this entity will help to clearly understand the pathogenesis, biologic behaviour, and any specific molecular alterations in the future.…”
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Targeted Therapy for Rheumatoid Arthritis in the New Era by WANG Jun, MENG Juan

“…The clinical manifestation of RA involves various organs and systems both inside and outside the joints, and often exhibits strong clinical heterogeneity with unclear pathogenesis. Ineffective drug treatment for severe arthritis can result in physical disability and severely decreased quality of life. …”
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Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease by Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao, Lijuan Wang

“…Conclusions Our findings reveal the role of pericyte-mediated fibrosis in depositing ECM in the pathogenesis of CSVD. EDB could improve symptoms and the underlying pathogenesis of CCH mice and decrease the expression of the fibrous profiles of pericytes and ECM proteins, which may be regulated by TGF-β1/ IL-11. …”
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Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus by Chen-xing Zhang, You-ying Mao, Yu-pin Tan, Mei-yu Zhang, Kang Shao, Shu-jun Wang, Ping Ji, Jia-yuan Wang, Lei Yin, Ying Wang

“…Previous reports have implicated IFN-α in the pathogenesis of SLE. Up to date, however, no research has ever investigated the effect of IFN-α on CD8+T cells, which might be implicated in the pathogenesis of SLE. …”
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The role of Nrf2 transcription factors in various physiological and pathological states by Deasyka Yastani, Sri Widia A Jusman

“…Understanding Nrf2's diverse functions offers valuable insights into disease pathogenesis and potential therapeutic approaches. This review explores the pleiotropic role of Nrf2 regulation. …”
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Microbiome role in pancreatic diseases development by Yu. V. Evsyutina, V. T. Ivashkin

“…To present the modern concept on the mechanisms of pancreatic disease development and role of intestinal and oral microbiome in pancreatitis pathogenesis. Summary. Intestinal barrier dysfunction, bacterial overgrowth syndrome and endotoxinemia are features of acute pancreatitis. …”
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Air Pollution and Respiratory Permeability in Obstructive Sleep Apnea — A Review by Nguyen Thanh Tung, Hoang Ba Dung, Tran Phan Chung Thuy, Huynh Nguyen Xuan Thao, Hsiao-Chi Chuang

“…This review article explored the role of air pollution and airway permeability in the pathogenesis of OSA.…”
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Application of immunohistochemical markers in mycosis fungoides by SHAO Kaixin, LIU Xiangjun, TANG Zhenzhen

“…In-depth research on immunohistochemical markers helps better understand the pathogenesis of MF and provides a more accurate basis for clinical treatment, such as guiding the selection of treatment regimens and evaluating treatment effects, in addition to its indispensable role in the clinical management of MF. …”
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Oral lichen planus involving the palate: Case report and review of literature by Shahen Ali Ahmed, Ali Fakhree Alzubaidee

“…Women are most often affected and lichen planus is usually reported in individuals over 50 years of age The etiology of lichen planus is unknown at present and the disorder has been classified as a chronic disease of immune-mediated pathogenesis. The oral lesions are usually bilateral and involve the buccal mucosa in about 90 percent of all cases. …”
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Whether pH-metry and investigation of esophageal motor function are necessary for diagnosis and choice of therapy for us today? by O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…Assessment of physical and chemical properties of refluxate and parameters of peristalsis of the esophagus is necessary for establishment of etiology and pathogenesis of diseases that allows to prescribe specific treatment to the patient.…”
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Bowel diseases and constipation in practice of the obstetrician and gynecologist by I. V. Kuznetsova, Yu. B. Uspenskaya

“…To present up-to-date data on etiology, pathogenesis and treatment of constipation in women of various age groups and at combined gynecologic diseases.Summary. …”
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Koro Syndrome: Epidemiology, Psychiatric and Physical Risk Factors, Clinical Presentation, Diagnosis, and Treatment Options by Yukino N. Strong, David Y. Cao, Jessica Zhou, Maya A. Guenther, Danyon J. Anderson, Alan D. Kaye, Brian E. Blick, Prathima R. Anandi, Hirni Y. Patel, Ivan Urits

“…Additional investigation on the prevalence, pathogenesis, factors that correlate with treatment efficacy are needed to fully understand Koro syndrome.…”
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Metabolomic profiles as a new understanding of disease processes by O. Yu. Zolnikova, M. S. Reshetova, M. N. Ivanova, V. T. Ivashkin

“…Metabolomic profile changes in different types of diseases will help to improve understanding of the pathogenesis. New therapeutic approaches may be developed. …”
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Irritable bowel syndrome concept from the gut microbiom point of view by Anna F. Sheptulina, Vladimir T. Ivashkin

“…These in turn exert direct impact on quantitative and qualitative spectrum of gastrointestinal microbiota which changes, as it was demonstrated in the recent original studies, is an integral part of IBS pathogenesis and is the cornerstone of symptom origin of this func­ tional disorder. …”
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AAV-based vectors for human diseases modeling in laboratory animals by Timur I. Aliev, Dmitry V. Yudkin

“…The development of therapeutic drugs and vaccines requires the availability of appropriate model animals that replicate the pathogenesis of human diseases. Both native and transgenic animals can be utilized as models. …”
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Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment by Liang Peng, Yi Lai, Baodi Cao

“…These vesicles, released by cells into the extracellular space, are pivotal in the pathogenesis of EOC. In addition, sEVs show significant promise as biomarkers and therapeutic agents for the treatment and management of this malignancy. …”
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Integrative prognostic modeling of ovarian cancer: incorporating genetic, clinical, and immunological markers by Aidi Lin, Feifei Xue, Chenxiang Pan, Lijiao Li

“…Abstract Ovarian cancer has a high mortality rate, primarily due to late diagnosis and complex pathogenesis. This study develops an integrative prognostic model combining genetic, clinical, and immunological data to predict outcomes in ovarian cancer patients. …”
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Oxidative stress in viral hepatitis by Huseyin Erdal, Hacer Ozlem Kalayci

“…Accumulating evidence suggests that oxidative stress (OS) plays a pivotal role in the pathogenesis and progression of viral hepatitis. OS occurs due to a disproportion between reactive oxygen species (ROS) generation and antioxidant protection, resulting in damage to cells and tissues. …”
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Melatonin and its therapeutic prospects in gastroenterology by A. A. Svistunov, Mikhail A. Osadchuk, A. M. Osadchuk

“…The melatonin role in pathogenesis and prognosis of digestive diseases is covered. …”
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