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141
Air Pollution and Respiratory Permeability in Obstructive Sleep Apnea — A Review
Published 2020-11-01“…This review article explored the role of air pollution and airway permeability in the pathogenesis of OSA.…”
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142
Oral lichen planus involving the palate: Case report and review of literature
Published 2021-02-01“…Women are most often affected and lichen planus is usually reported in individuals over 50 years of age The etiology of lichen planus is unknown at present and the disorder has been classified as a chronic disease of immune-mediated pathogenesis. The oral lesions are usually bilateral and involve the buccal mucosa in about 90 percent of all cases. …”
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143
Whether pH-metry and investigation of esophageal motor function are necessary for diagnosis and choice of therapy for us today?
Published 2010-04-01“…Assessment of physical and chemical properties of refluxate and parameters of peristalsis of the esophagus is necessary for establishment of etiology and pathogenesis of diseases that allows to prescribe specific treatment to the patient.…”
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144
Bowel diseases and constipation in practice of the obstetrician and gynecologist
Published 2015-03-01“…To present up-to-date data on etiology, pathogenesis and treatment of constipation in women of various age groups and at combined gynecologic diseases.Summary. …”
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145
Metabolomic profiles as a new understanding of disease processes
Published 2022-05-01“…Metabolomic profile changes in different types of diseases will help to improve understanding of the pathogenesis. New therapeutic approaches may be developed. …”
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146
Irritable bowel syndrome concept from the gut microbiom point of view
Published 2018-08-01“…These in turn exert direct impact on quantitative and qualitative spectrum of gastrointestinal microbiota which changes, as it was demonstrated in the recent original studies, is an integral part of IBS pathogenesis and is the cornerstone of symptom origin of this func tional disorder. …”
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147
AAV-based vectors for human diseases modeling in laboratory animals
Published 2025-02-01“…The development of therapeutic drugs and vaccines requires the availability of appropriate model animals that replicate the pathogenesis of human diseases. Both native and transgenic animals can be utilized as models. …”
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148
Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment
Published 2025-02-01“…These vesicles, released by cells into the extracellular space, are pivotal in the pathogenesis of EOC. In addition, sEVs show significant promise as biomarkers and therapeutic agents for the treatment and management of this malignancy. …”
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149
Integrative prognostic modeling of ovarian cancer: incorporating genetic, clinical, and immunological markers
Published 2025-02-01“…Abstract Ovarian cancer has a high mortality rate, primarily due to late diagnosis and complex pathogenesis. This study develops an integrative prognostic model combining genetic, clinical, and immunological data to predict outcomes in ovarian cancer patients. …”
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150
Melatonin and its therapeutic prospects in gastroenterology
Published 2018-08-01“…The melatonin role in pathogenesis and prognosis of digestive diseases is covered. …”
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151
Psoriasis: Unraveling Disease Mechanisms and Advancing Pharmacological and Nanotechnological Treatments
Published 2025-02-01“…Miao Miao,1 Jiong Yan,2 Yujin Sun,3 Jia Liu,2 Shun Guo2 1Outpatient Department, Disease Prevention and Control Center of Tongshan District, Xuzhou, People’s Republic of China; 2Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 3Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of ChinaCorrespondence: Jia Liu; Shun Guo, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Qinhuai District, Nanjing, Jiangsu Province, 210029, People’s Republic of China, Email aliceyoyo1986@163.com; 260873@njucm.edu.cnAbstract: Research into the pathogenesis of inflammatory skin diseases, including dermatitis and psoriasis, has yielded significant advancements in the last decades. …”
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152
The intestinal microbiome as a separate organ
Published 2014-12-01“…Due to difference in sampling methods it is difficult to draw clear-cut conclusions on microflora role in pathogenesis for scientific investigations. Analysis of sequential cloning of 16S ribosomal RNA possesses the highest information value of all up-to-date methods. …”
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153
COVID-19 Pandemic and Irritable Bowel Syndrome — is there a Relationship?
Published 2022-08-01“…These factors dictate the need for an integrated approach in the management of such a group of patients with the use of modern multi-target drugs that affect the pathogenetic factors in the formation of functional gastrointestinal diseases, one of which is the Kolofort drug due to the triple multi-target mechanism of action on the pathogenesis of functional gastrointestinal diseases.…”
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154
Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients
Published 2025-02-01“…Understanding its pathogenesis and revealing predictive biomarkers are essential for guiding treatment decisions. …”
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155
Relationship between programmed cell death and targeted therapy for thyroid cancer in patients with a poor prognosis: an update
Published 2025-02-01“…However, the detailed mechanisms of pathogenesis are still unclear. Therefore, a comprehensive understanding of the underlying carcinogenesis mechanisms of thyroid cancer is required. …”
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156
PGC-1α activation to enhance macrophage immune function in mycobacterial infections.
Published 2025-01-01“…Nontuberculous Mycobacteria (NTM) are a heterogeneous group of environmental microorganisms with distinct human pathogenesis. Their incidence and prevalence are rising worldwide, due in part to elevated antimicrobial resistance which complicates treatment and potential successful outcomes. …”
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157
The Science of Memory Loss: Insights into Alzheimer’s Disease
Published 2025-02-01“…Since the 2016 Seminar, substantial progress has been made in understanding AD’s complex pathogenesis, identifying genetic risk and protective factors, and developing novel diagnostic biomarkers and therapeutic strategies. …”
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158
Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases
Published 2025-02-01“…This review delves into the emerging significance of TRIM family proteins in the pathogenesis of idiopathic pulmonary fibrosis (IPF), asthma, chronic obstructive pulmonary disease (COPD), and pulmonary hypertension (PH). …”
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159
COVID-19 and post-disease features in patients with obesity
Published 2024-12-01“…Many countries were forced to promptly reorganize their healthcare system in order to save patients with COVID-19. The pathogenesis and specifics of the disease are not completely understood, but one pattern is particularly clear: COVID-19 tends to be more severe in people with obesity. …”
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160
Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer
Published 2025-02-01“…The hedgehog signaling pathway, a critical mediator in the normal development of numerous organs and the pathogenesis of cancer, is typically quiescent but is aberrantly activated in several malignancies. …”
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