PRKD2 as a novel target for targeting the diabetes–osteoporosis nexus by Rongjin Chen, Chenhui Yang, Hefang Xiao, Ao Yang, Changshun Chen, Fei Yang, Bo Peng, Bin Geng, Yayi Xia

“…The aim of this study was to identify and validate key genes implicated in the pathogenesis of both conditions. By employing the Mfuzz time-series gene clustering method combined with transcriptome sequencing of patient serum, we systematically delineated gene expression patterns during the transition from a healthy state through DM to DMOP. …”
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Diagnostics and treatment of biliary dyskinesia: clinical guidelines of the Russian gastroenterological Association by V. T. Ivashkin, I. V. Mayev, Yu. O. Shulpekova, Ye. K. Baranskaya, A. V. Okhlobystin, A. S. Trukhmanov, T. L. Lapina, A. A. Sheptulin

“…The gallbladder dyskinesia and sphincter of Oddi dyskinesia are defined as the diseases of functional origin caused by motility and visceral sensitivity disorders. The pathogenesis of these disorders is not completely understood. …”
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Lipedema: Clinical Features, Diagnosis, and Management by Hatan Hisham Mortada, Abdulmalek W. Alhithlool, Nouf Z. AlBattal, Rashika K. Shetty, Ghaleb A. AL-Mekhlafi, Joon Pio Hong, Feras Alshomer

“…There have been relatively few studies that have precisely defined the pathogenesis, epidemiology, and treatment approaches for lipedema. …”
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Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing by Ye Jin Ha, Seong-Hwan Park, Seon-Kyu Kim, Ka Hee Tak, Jeong-Hwan Kim, Chan Wook Kim, Yong Sik Yoon, Seon-Young Kim, Jong Lyul Lee

“…These datasets enhance our understanding of PMP pathogenesis and provide a valuable resource for uncovering the intricate molecular landscape of PMP, with the potential to improve clinical utility through further research.…”
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Link between bilaterality and type 2 inflammation in respiratory epithelial adenomatoid hamartomas: A two-center retrospective cohort study. by Yujin Heo, Sang Duk Hong, Hyo Yeol Kim, Gwanghui Ryu, Kyung Won Kwon, Yong Gi Jung

“…<h4>Background</h4>Sinonasal respiratory epithelial adenomatoid hamartomas (REAH) are rare benign lesions with diverse clinical characteristics. Their pathogenesis remains unclear, with hypotheses suggesting either an inflammatory process or neoplastic origin. …”
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Options of dyslipidemia treatment at non-alcoholic fatty liver disease by M. V. Mayevskaya, M. A. Morozova

“…Conclusion. Now data on a pathogenesis of lipid metabolism disorders at NAFLD are accumulated. …”
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Plasma mcfDNA Sequencing May Improve Usual Care Diagnostics to Detect HHV-8 Among Outpatient People with Advanced HIV by Sarah Park, Brian Epling, Morgan Richey, Daniel Lupu, Mona Mughar, Irini Sereti

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Assessment of Interleukin-1β in Saliva of Smoker and Non-smoker Patients with Chronic Periodontitis. by Solav Abdul-Qadir Mustafa, Haween T. Nanakaly, Hozan Wrya Azeez

“… Background and objectives: Smoking is considered a significant risk factor in periodontitis. The pathogenesis of periodontal disease may be affected by alterations of the inflammatory response by smoke. …”
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Review of Russian Abstracts Accepted for United European Gastroenterology Week (2022) by A. A. Sheptulin

“…The abstracts were devoted to topical issues of pathogenesis, diagnosis and treatment of intestinal liver and pancreatic diseases.Conclusion. …”
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A Peculiar Tracheoesophageal Fistula Caused by a Plastic Foreign Body by Chao Chen, Dingyuan Dai, Yu Guo, Chen Sun, Qi Li

“…The report investigates the unusual trajectory of this case—examining the pathway through which the foreign body became lodged in the trachea, followed by the subsequent development of TEF—and provides valuable insights into its pathogenesis and clinical significance.…”
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Bacterial overgrowth syndrome by Yu. A. Kucheryavy, T. S. Oganesyan

“…To present the up-to-date information on pathogenesis, diagnostics and treatment of bacterial overgrowth syndrome (BOS).Original positions. …”
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Relationship between Abnormal Lipid Metabolism and Gallstone Formation by Xiang Li, Xiaodan Yin, Jun Xu, Lei Geng, Zhengtao Liu

“…Therefore, recent research literature on the genes, proteins, and molecular substances involved in lipid metabolism during the pathogenesis of gallstones has been conducted. This study aimed to determine the role of lipid metabolism in the pathogenesis of gallstones and provide insights for future studies using previous research in genomics, metabolomics, transcriptomics, and other fields.…”
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Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential by Mi-bo Tang, Yi-xuan Liu, Zheng-wei Hu, Hai-yang Luo, Shuo Zhang, Chang-he Shi, Yu-ming Xu, Yu-ming Xu, Yu-ming Xu

“…There is emerging evidence indicating a protective role of PGC-1α in the pathogenesis of several neurological diseases. As such, a deeper and broader understanding of PGC-1α and its role in neurological diseases is urgently needed. …”
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Cytokines in Liver Cirrhosis (Their Importance in Assessing Activity and Decompensation) by G. K. Mirodzhov, S. D. Pulatova

“…Aim: studying the role of pro-inflammatory and anti-inflammatory cytokines in the pathogenesis of liver cirrhosis progression.Materials and methods. …”
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Modern approaches to functional dyspepsia treatment by A. A. Sheptulin

“…Investigation of FD pathogenesis should be continued that will provide more differentiated treatment approach and improve the results.…”
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Gastroesophageal reflux disease and functional dyspepsia: clinical efficacy and safety of prokinetic choice by D. I. Trukhan

“…Motility disorder of gastroesophageal zone plays a leading part in pathogenesis of these diseases that assumes application prokinetics as a baseline therapy. …”
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Non-invasive imaging with ICOS-targeting monoclonal antibody for preclinical diagnosis of rheumatoid arthritis in a humanized mouse model by Shao Duan, Chao Li, Feng Yan, Yifei Xia, Shuaiming Shao, Weiyu Chen, Zunyu Xiao, Gongping Xu

“…Abstract Background Activated T cells play a pivotal role in rheumatoid arthritis (RA) pathogenesis, and imaging of activated T cells may provide a non-invasive tool for RA detection. …”
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Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disea... by Yasaman Nazari Hagh, Mohamadreza Ahmadifard, Sedigheh Esmaelzadeh, Soheila Abbaszadeh, Naser Shokrzadeh

“…Some genetic markers play a crucial role in pathogenesis and infertility. Objective: This study investigates the role of miR-200a and miR-223-3p in embryo implantation and their association with EM-related infertility. …”
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Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…The need for advanced analytical tools to better understand the pathogenesis of cardiovascular disease (CVD) is critical due to its significant impact on public health. …”
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Thyroid Storm Triggered by Rotavirus Infection in a 10-Year-Old Girl by Masazumi Miyahara, Shizuka Otsuki

“…Our case highlights the need for further investigation into the potential triggering pathogens in patients with TS to better clarify details regarding the patient’s status or disease pathogenesis.…”
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