Coexistence of giant cell arteritis and subacute thyroiditis: A case report and literature review by Cheng Xu, Yongmei Han

“…Giant cell arteritis and subacute thyroiditis are often regarded as clinically distinct diseases with differing pathogenesis. We report a rare case of coexisting giant cell arteritis and subacute thyroiditis that were both successfully managed using glucocorticoid therapy. …”
Get full text

Role of serotonin in physiology and diseases of gastro-intestinal tract by E. F. Barinov, O. N. Sulayeva

“…It determines its involvement in pathogenesis of the diseases related to disorders of motility, microcirculation, inflammation and disregeneration. …”
Get full text

Clinical presentation, diagnosis and treatment of intrahepatic cholestasis of pregnancy by Yu. B. Uspenskaya, A. A. Sheptulin

“…To present the modern concept of etiology and pathogenesis of the intrahepatic cholestasis of pregnancy (ICP) and the modern diagnostic and treatment approaches to gastroenterologists. …”
Get full text

Liver Damage in Type 1 Diabetes Mellitus by A. O. Bueverov, A. V. Zilov

“…An up-to-date review of the prevalence, pathogenesis, diagnosis and management of hepatological complications of type 1 diabetes mellitus (T1D).Key points. …”
Get full text

Irritable bowel syndrome: pathophysiological and clinical issues by V. T. Ivashkin, Ye. A. Poluektova

“…To discuss the issues of etiology, pathogenesis, clinical presentation and differential diagnostics of irritable bowel syndrome (IBS).Summary. …”
Get full text

Ferroptosis: mechanism and role in diabetes-related cardiovascular diseases by Ziyi Wang, Chao Wu, Dong Yin, Kefei Dou

“…This review summarizes ferroptosis-related mechanisms in the pathogenesis of diabetic cardiovascular diseases and novel therapeutic choices targeting ferroptosis-related pathways. …”
Get full text

Pathogenetic Aspects of Oral Cavity Lesions in Inflammatory Gastrointestinal Tract Diseases by N. S. Robakidze, O. B. Shchukina

“…Despite the similarity of many pathogenetic lesions of the gastrointestinal tract and the oral cavity, there remain unresolved issues related to the etiology and pathogenesis of dental diseases associated with inflammatory bowel diseases.Aim. …”
Get full text

The theses for PhD degree by article Editorial

“…Tarasova – The role of nutritional deficiency of selenium, zinc and manganese in pathogenesis of chronic gastritis and duodenal peptic ulcer (evidence from Chuvash Republic).M.A. …”
Get full text

PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation. by Lujie Zhang, Yanni Gao, Haoran Zhou, Xiao Liang, Xiaolin Jiang, Wenqin Gong, Yangyang Sun, Desheng Zhang, Xianwei Wang, Hans Nauwynck, Juan Bai, Ping Jiang

“…Collectively, these results elucidate a novel mechanism of NLRP3 inflammasome activation during PRRSV-2 infection, providing valuable insights into PRRSV-2 pathogenesis.…”
Get full text

BCL6 (B-cell lymphoma 6) expression in adenomyosis, leiomyomas and normal myometrium. by Loreta Canivilo Salas, Bruna Mielczarski, Raquel Camara Rivero, João Sabino Lahogue da Cunha Filho, Ricardo Francalacci Savaris

“…These findings suggest that BCL6 plays a role in the pathogenesis of leiomyomas, potentially contributing to abnormal smooth muscle cell proliferation. …”
Get full text

Modern options of prokinetics in gastroesophageal reflux disease treatment by A. A. Sheptulin, A. A. Kurbatova, S. A. Baranov

“…Taken into account important role of esophageal and stomach dysmotility in GERD pathogenesis, prokinetics can be recommended for comprehensive disease treatment, especially at PPI inefficacy.…”
Get full text

Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Abstract Background There is growing evidence that the pathogenesis of Alzheimer's disease is closely linked to the resident innate immune cells of the central nervous system, including microglia and astrocytes. …”
Get full text

Editorial: Understanding biofilms: recent trends and developments by Sujogya Kumar Panda, Luis Cláudio Nascimento da Silva

Get full text

The theses for MD degree by article Editorial

“…Stepanov – Regulatory disorders in pathogenesis of irritable bowel syndrome in children.…”
Get full text

Prevention and treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage by Kyle McGrath, Grace Hey, Ghaidaa Ebrahim, Noah Gilberstadt, David Mahan, Brandon Lucke-Wold

“…Further investigation of the glymphatic system and its role in PHCV pathogenesis could result in novel pharmacologic targets. …”
Get full text

Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and... by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, T. L. Lapina, V. I. Simanenkov, K. A. Sokolov

“…In the treatment of functional gastrointestinal diseases characterized by multifactorial pathogenesis, preference should be given to multi-targeted therapy with the use of drugs that have an effect on its various links.…”
Get full text

Research progress of hypoxia-inducible factor-1α and zinc in the mechanism of diabetic kidney disease by Wei Qin, Ping Nie, Xuejun Hui, Fei Chen, Xingbao Hu, Wenjiao Shi, Manyu Luo, Bing Li

“…This article provides references and insights for further research on the pathogenesis and progression of diabetic kidney disease.…”
Get full text

Deep learning-based prediction of autoimmune diseases by Donghong Yang, Xin Peng, Senlin Zheng, Shenglan Peng

“…T cells, as a core component of the immune system, play a critical role in the human immune system and have a significant impact on the pathogenesis of autoimmune diseases. Several studies have demonstrated that T-cell receptors (TCRs) may be involved in the pathogenesis of various autoimmune diseases, which provides strong theoretical support and new therapeutic targets for the prediction and treatment of autoimmune diseases. …”
Get full text

Treatment of irritable bowel syndrome: the past, present and future by V. T. Ivashkin, Ye. A. Poluektova, O. S. Lyashenko, D. V. Reykhart

“…To present data on foreign and Russian clinical studies devoted to improvement of irritable bowel syndrome (IBS) treatment according to the new data on disease pathogenesis.Summary. Spasmolytics, laxatives or antidiarrheal agents are traditionally applied for treatment of IBS patients according to leading symptom. …”
Get full text

Unraveling the microbial mysteries: gut microbiota’s role in ulcerative colitis by Keyu Ren, Chunming Yong, Yanchun Jin, Shanwei Rong, Kuijin Xue, Bin Cao, Hongyun Wei

“…Additionally, the role of extra-intestinal microbiota in UC pathogenesis is explored, which has been less studied but is gaining attention. …”
Get full text