Clearance of Intracellular Pathogens with Hyaluronic Acid Nanomicelles Responsive to H₂S and pH by Jun Luo, Hui Huang, Junfeng Jiang, Wenyu Zheng, Peng Chen, Hongjin Bai

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Analysis of the pathogenicity and pathological characteristics of NOTCH3 gene-sparing cysteine mutations in vitro and in vivo models by Zhenping Gong, Wan Wang, Ying Zhao, Yadan Wang, Ruihua Sun, Ruihua Sun, Haohan Zhang, Haohan Zhang, Fengyu Wang, Yaru Lu, Jiewen Zhang, Jiewen Zhang, Jiewen Zhang, Jiewen Zhang

“…With the development of gene sequencing technology, cysteine-sparing mutations can also cause CADASIL disease, however, the pathogenicity and pathogenic mechanisms of cysteine-sparing mutations remain controversial.ObjectiveTo analyze the pathogenicity and pathological features of cysteine-sparing mutations in both in vitro and in vivo mouse models.MethodsA cysteine-sparing mutant of NOTCH3ECD R75Q was constructed by lentiviral transfection in vitro, and the NOTCH3 R75Q knock-in mouse model was constructed by CRISPR/Cas-mediated genome engineering in vivo. …”
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Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes by Setareh Mamishi, Reihaneh Hosseinpour Sadeghi, Sadaf Sajedi Moghaddam, Babak Pourakbari, Shiva Poormohammadi, Maryam Sotoudeh Anvari, Shima Mahmoudi

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Bacterial profile and resistance trends of pathogens implicated in bacterial meningitis: A four years retrospective study by Lamia EL Moussely, Nashwa Omar, Nahla Hanafy, Manal Darwish

“…Antimicrobial resistance was predominantly against ceftriaxone 89%, and ampicillin 87.9%. Conversely, pathogens exhibited greater sensitivity to tobramycin (46.2%) and gentamicin (43.1%) than other antimicrobials. …”
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Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients by L. Johana Madroñero, Eliana P. Calvo, Carolina Coronel-Ruiz, Myriam L. Velandia-Romero, María Angélica Calderón-Peláez, Jhann A. Arturo, Adriana P. Franco-Rodríguez, Ricardo Gutiérrez-Pérez, Lady S. López, Félix G. Delgado, Sigrid J. Camacho-Ortega, Lilia J. Bernal-Cepeda, Sonia P. Bohórquez, Jaime E. Castellanos

“…Compared to patients who recovered from COVID-19, patients who died exhibited a microbiome enriched in periodontal and pathogenic bacteria such as Klebsiella pneumoniae. Our results highlighted a dual relationship between SARS CoV-2 infection and an exacerbated periodontopathogen-induced immune response.…”
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Respiratory pathogen spectrum and epidemiological trends in Hainan Province: a retrospective analysis from 2017 to 2023 by Lvying Wu, Jianan Zhang, Zhiming Wu, Hua Pei, You Zhang

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Comprehensive analysis of causal pathogens and determinants influencing black rot disease development in MD2 pineapples by Manori Kuruppu, Yasmeen Siddiqui, Hala Badr Khalil, Hala Badr Khalil

“…This study was conducted to identify the principal causative pathogen of black rot disease in pineapple from three different regions. …”
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[Intro] Standards and Their Containers: Introduction to the Thematic Issue on Histories of Microbial Pathogens from the Colonial to the Postcolonial Eras by Aro Velmet, Claas Kirchhelle

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Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity by Wassim Daher, Vincent Le Moigne, Yara Tasrini, Shweta Parmar, Danielle L. Sexton, John Jairo Aguilera-Correa, Valentin Berdal, Elitza I. Tocheva, Jean-Louis Herrmann, Laurent Kremer

“…These findings demonstrate that both ESX systems drive M. abscessus pathogenicity.…”
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Surface-Functionalised Copper Oxide Nanoparticles: A Pathway to Multidrug-Resistant Pathogen Control in Medical Devices by James Hall, Subbareddy Mekapothula, Rebecca Coxhill, Dominic Craske, Adam M. Varney, Gareth W. V. Cave, Samantha McLean

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Multidrug Resistant Enteric Bacterial Pathogens in a Psychiatric Hospital in Ghana: Implications for Control of Nosocomial Infections by Kwabena O. Duedu, George Offei, Francis S. Codjoe, Eric S. Donkor

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Antibacterial Activity and Mechanisms of Action of Inorganic Nanoparticles against Foodborne Bacterial Pathogens: A Systematic Review by Abayeneh Girma, Birhanu Abera, Bawoke Mekuye, Gedefaw Mebratie

“…Foodborne disease outbreaks due to bacterial pathogens and their toxins have become a serious concern for global public health and security. …”
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Genomic characterizations of Klebsiella variicola: emerging pathogens identified from sepsis patients in Ethiopian referral hospitals by Melese Hailu Legese, Daniel Asrat, Adane Mihret, Badrul Hasan, Abraham Aseffa, Göte Swedberg

“…The isolation of multidrug-resistant K. variicola as an emerging sepsis pathogen calls for strong infection prevention strategies and antimicrobial stewardship supported by advanced bacterial identification techniques.…”
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Uptake of Risk‐Reducing Salpingo‐Oophorectomy and Gynaecologic Surveillance Among Germline BRCA Pathogenic Variants Carriers by Alessandra Inzoli, Serena Negri, Cristina Dell'Oro, Clarissa Costa, Liliana Marchetta, Mariaclara Boccadutri, Simona Fumagalli, Gaia Roversi, Elena Maria Sala, Chiara Celi, Valentina Rossi, Robert Fruscio

“…ABSTRACT Introduction Risk‐reducing salpingo‐oophorectomy (RRSO) is recommended by international guidelines in women with BRCA1/2 germline pathogenic variants (PV) to prevent ovarian cancer. …”
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Antibacterial Potential of Endemic Medicinal Plants of the Maluku Islands, Indonesia, against Urinary Tract Infection Pathogens by Eka Astuty, Vinsa Delia Luhulima, Stefanus Cahyo Ariwicaksono

“…The medicinal plant extraction was conducted using the maceration method. The pathogens were isolated using the dilution method. …”
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Changes in infant respiratory pathogens pre-, during, and post-COVID-19 non-pharmacological interventions in Beijing by Tongying Han, Yajuan Wang, Di Zhang, Ying Li, Li Zhang, Jin Yan, Chi Li, Shengnan Yang, Litao Guo, Huijuan Yan

“…Abstract Background To explore the effect of non-pharmacological interventions (NPIs) on respiratory pathogen profiles among hospitalized infants aged 0–3 months in Beijing during the coronavirus disease 2019 (COVID-19) pandemic. …”
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Impact of soil legacy on plant–soil feedback in grasses and legumes through beneficial and pathogenic microbiota accumulation by Mohamed Idbella, Ahmed M. Abd-ElGawad, Fatima Ezzahra Chouyia, Giuliano Bonanomi, Giuliano Bonanomi

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Physical Inactivation of Monodon Baculovirus (Mbv), a Pathogenic Virus of Tiger Prawn (Penaeus Monodon Fab.) by M. Alifuddin

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Diagnostic performance of the DISQVER metagenomic sequencing tool for the identification of pathogens in febrile neutropenic patients: the ADNEMIA trial by Geneviève Héry-Arnaud, Christophe Burucoa, Marie Kempf, David Boutoille, Yohann Foucher, Philippe Lanotte, Maxime Pichon, Stéphane Corvec, Cécile Le Brun, Helene Pailhories

“…Considering that without an identified pathogen, a 10% mortality rate can ensue, documentation is essential to the optimisation of antibiotic therapy. …”
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Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae by Chang Liu, Yi Wei, Yuejia Dang, Wajjiha Batool, Xiaoning Fan, Yan Hu, Zhengquan He, Shihong Zhang

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