Antibacterial Effect of Fixed and Volatile Oils against Gram-positive and Gram-negative Bacteria by Tara Faiq M. Salih, Sakar Ahmed Abdullah, Salar Ibrahim Ali, Daryan Kamal Khder

“…Antibiotic resistance phenomena among pathogenic bacteria considered as a major health problem ?…”
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Engineering and design of a COF-coated probe for the detection and removal of flumequine and enrofloxacin antibiotics in foodstuffs: a molecular dynamics simulation approach by Alireza Nakhaei, Heidar Raissi, Maryam Alaei, Farzaneh Farzad

“…However, their overuse can lead to significant health risks, including water contamination, antibiotic-resistant pathogens, kidney disease, reproductive disorders, cancers, and severe allergic reactions. …”
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High mortality rates and long-term complications in children with infectious brainstem encephalitis: A study of sixteen cases. by Yuanyuan Zhou, Yi Zhu, Lingfeng Cao, Yingyan Shi, Jun Shen

“…Fewer studies have been conducted on the incidence, clinical manifestations, pathogens and post-infectious sequelae of pediatric infectious BE.…”
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Algorithm of management of patient with alcohol-induced liver disease by M. V. Mayevskaya, M. A. Morozova

“…The aim of review. To present main pathogenic aspects of development of alcohol-induced liver disease (ALD), principles of diagnostics and treatment of this disease.Original positions. …”
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Hepatoprotective effects of propolis ethanol extract on D-galactose-induced aging mice: A metabolomics and transcriptomics analysis focusing on insulin resistance pathways by Jinjia Liu, Songhao Tian, Jixiang Wang, Qing Sang, Wenting Su, Jinqiang Wu, Fenglei Zai

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Synthesis, Characterization and Antibacterial activity of Benzimidazole Derivatives and their Cu (ii),Ni (ii) and Co (ii) complexes by Haftom Welderufael, Dagne Addisu Kure, Endalkachew Asefa Moges, Lelisa File, Salah Hamza Sherif

“…This compound is a good starting point to develop new drug for treating pathogenic diseases. Therefore, synthesis of more analogue were recommended for further discovery of a new drug candidate. …”
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Acute hepatitis of non-specified etiology by Ye. V. Tsyganova, O. O. Znoyko, N. D. Yushchuk, K. R. Dudina, M. G. Isagulyants, N. V. Petrakova, T. V. Petrova, M. I. Mikhaylov

“…Aim of investigation. To estimate pathogenic and diagnostic value of detection of hepatotropic viruses components (DNA, RNA, antigens) and antiviral immune response at acute hepatitis of non-specified etiology by the methods of enzyme-linked immunoassay (EIA), polymerase chain reaction (PCR) and Т-cellular lymphocytes proliferation in response to HCV antigens stimulation.Methods. …”
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Water Hyacinth, an Invasive Species in Africa: A Literature Review by Lubembe, Sharon Indasi, Okoth, Sharon, Turyasingura, Benson, Oyugi, Timothy, Ibarasa, Hillary, Moenga, Kelvin, Chavula, Petros, Tumushabe, Jennifer Turyatemba

“…Water hyacinth Pontederia crassipes (Eichhornia crassipes) has proliferated rapidly in African inland waters, posing numerous threats to fisheries by reducing the existence of some species; water quality by lowering levels of dissolved oxygen; human health and the environment by introducing various disease causing pathogens and harbouring dangerous animals. The hyacinths further impact human activities by blocking waterways for fishing and destroying habitat for some fish to bread properly. …”
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Staphylococcal skin infection isolates from dogs without recent antibiotic exposure are 100% susceptible to clindamycin by W. Cooper Brookshire, Larry D. Ballard, Vernon C. Langston, Joo Youn Park, Keun-Seok Seo

“…Antibiotic susceptibility testing was performed on 67 pathogenic canine staphylococcal isolates (62 Staphylococcus pseudintermedius and 5 Staphylococcus schleiferi) from patients who met the study inclusion criteria, and 100% of isolates were susceptible to antibiotics commonly prescribed for canine staphylococcal skin infections, including clindamycin. …”
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Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax by Caroline A. Coughlin, Dhanvantri Chahar, Marianna Lekakis, Abdessamad A. Youssfi, Lingxiao Li, Evan Roberts, Natalia Campos Gallego, Claude-Henry Volmar, Ola Landgren, Shaun Brothers, Anthony J. Griswold, Catalina Amador, Daniel Bilbao, Francesco Maura, Jonathan H. Schatz

“…Abstract Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. …”
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Genomic analysis of Enterobacter cloacae complex from Southern Thailand reveals insights into multidrug resistance genotypes and genetic diversity by Thunchanok Yaikhan, Kamonnut Singkhamanan, Pawarisa Luenglusontigit, Arnon Chukamnerd, Natakorn Nokchan, Nutwadee Chintakovid, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Kittinun Leetanaporn, Surasak Sangkhathat, Komwit Surachat

“…Abstract In this study, we conducted a comprehensive investigation into the Enterobacter cloacae complex (ECC), a group of notorious pathogens responsible for various hospital-acquired infections. …”
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In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction by Shafaat Hossain, Omar Hamza Bin Manjur, Mst Sharmin Sultana Shimu, Tamanna Sultana, Mustafizur Rahman Naim, Shahariar Siddique, Abdullah Al Mamun, Md Miftaur Rahman, Md Abu Saleh, Md Rakibul Hasan, Tania Rahman

“…Cystatin A (CSTA) functions as a cysteine protease inhibitor by forming tight complexes with the cathepsins. Pathogenic mutations in the CSTA gene can disrupt this interaction, potentially leading to physiological ailments. …”
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Unmasking MRSA antibiotic resistance: the impact of environment, pollution, and healthcare quality—a nationwide exploration in China: a comprehensive analysis spanning 2014 to 2021... by Yi-Chang Zhao, Ming-Xuan Xiao, Zhi-Hua Sun, Jia-Kai Li, Huai-yuan Liu, Bi-Kui Zhang, Hua-Lin Cai, Wei Cao, Feng Yu, Miao Yan

“…Abstract Background The rise of antibiotic resistance has become a critical global health concern, resulting in numerous fatalities annually. Among resistant pathogens, methicillin-resistant Staphylococcus aureus (MRSA) poses a particularly severe and expanding threat. …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“…Following the initial injury, it has been demonstrated that the immune system plays a key role in early inflammation, tissue regeneration, and the response against pathogens. In this study, the performance of laboratory determinations as biomarkers of prognosis in acute burned patients was evaluated in a retrospective case-control protocol. …”
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Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action by Aurangzeb Sana, Aurongzeb Muhammad, Shamim Shahbaz, Rashid Yasmeen, Khan Khalid Mohammed, Aziz Tariq, Alharbi Metab, Alasmari Abdullah F.

“…The objective of this research was to identify certain promising drug candidates that could excessively stimulate the HslV protease, leading to uncontrolled protein breakdown in the pathogens. Four dihydropyrimidone derivatives have been identified as potential activators of HslV protease exhibiting high docking scores, favorable binding patterns, and significant in vitro activation capabilities. …”
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Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn by Helena Miriam Lorenzo Juanes, Amparo López-Bernus, Belen Vicente, Montserrat Alonso-Sardón, Beatriz Rodríguez Alonso, Josue Pendones Ulerio, Pedro Fernandez Soto, Juan Luis Muñoz Bellido, Antonio Muro, Moncef Belhassen-García

“…Although the risk is considered very low in these collectives, clinicians should be alert to the possibility of new CCHF cases, given the high pathogenicity of CCHFV and the risk of transmission.…”
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Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey by Emil Vilstrup Moen, Thomas Skovhus Prior, Michael Kreuter, Wim A. Wuyts, Maria Molina-Molina, Marlies Wijsenbeek, Antonió Morais, Argyrios Tzouvelekis, Christopher J. Ryerson, Fabian Caro, Ivette Buendia-Roldan, Jesper M. Magnusson, Joyce S. Lee, Julie Morisett, Justin M. Oldham, Lauren K. Troy, Manuela Funke-Chambour, Maria Laura Alberti, Raphael Borie, Simon L. F. Walsh, Sujeet Rajan, Yasuhiro Kondoh, Yet H Khor, Elisabeth Bendstrup

“…Many respondents were unaware of specific genetic testing methods. Pathogenic genetic variants were seen as a potential contraindication for lung transplantation in 6–8% of respondents. …”
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Bioactive phytochemical compounds characterization, anti-oxidant and anti-microbial activity of the methanol and acetonitrile leaf extracts of Pithecellobium dulce by M. Kiranmayee, K. Riazunnisa

“…Purpose: The aim of this investigation is to demonstrate the phytochemical profiling of methanol and acetonitrile leaf extracts of P. dulce and evaluate their antioxidant activity and antibacterial potential against pathogenic bacteria. Materials and methods: The methanol and acetonitrile extracts of P. dulce leaf were extracted and characterized by using GCMS– and FTIR. …”
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Antimicrobial and antiproliferative activity of biosynthesized manganese nanocomposite with amide derivative originated by endophytic Aspergillus terreus by Nashwa El-Gazzar, Reem Farouk, Nervana S. Diab, Gamal Rabie, Basel Sitohy

“…Conclusion The use of HDOCOX, either alone or in combination with MnNPs, is a potential candidate for inhibiting pathogenic microbes and the development of an anticancer drug pipeline.…”
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Interaction of the gastroenterologist and psychiatrist at management of patient with functional disorder of gastro-intestinal tract by V. T. Ivashkin, Ye. A. Poluektova, A. G. Beniashvili

“…More and more doctors recognize pathogenic relation between psychological disorders and physical symptoms without obvious organic substrate and, therefore — necessity of creation of interdisciplinary alliances to provide qualified aid to considerable number of such patients.…”
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