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  1. 441
  2. 442

    Phages as potential life-saving therapeutic option in the treatment of multidrug-resistant urinary tract infections by Beata Zalewska-Piątek, Michalina Nagórka

    Published 2025-02-01
    “…Phage therapy (PT) has emerged as a promising alternative due to its specificity, safety and efficacy against multidrug-resistant (MDR) pathogens causing infectious diseases. PT demonstrates significant potential in treating chronic and recurrent UTIs, also including catheter-associated infection by reducing bacterial biofilms, delaying catheter blockage, and enhancing antibiotic efficacy when used in combination. …”
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  3. 443

    Application of phytosynthesized silver nanoparticles (SNPs) against Erwinia amylovora causing fire blight disease by Saeed Tarighi, Meysam Soltani Nejad

    Published 2025-02-01
    “…Numerous studies have demonstrated their ability to exhibit antibacterial properties against a wide range of human and animal pathogens. In this investigation, the dimensions of SNPs were ascertained by employing aqueous extracts derived from apple, pear, and quince leaves. …”
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  4. 444

    A biallelically active embryonic enhancer dictates GNAS imprinting through allele-specific conformations by Yorihiro Iwasaki, Monica Reyes, Harald Jüppner, Murat Bastepe

    Published 2025-02-01
    “…Therefore, a biallelically active embryonic enhancer dictates GNAS imprinting via different chromatin conformations, underlying the allele-specific pathogenicity of STX16-ICR microdeletions.…”
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  5. 445

    Micromechanical behavior of the apple fruit cuticle investigated by Brillouin light scattering microscopy by Timm Landes, Bishnu P. Khanal, Hans Lukas Bethge, Tina Lehrich, Maximilian Seydi Kilic, Franz Renz, Miroslav Zabic, Moritz Knoche, Dag Heinemann

    Published 2025-02-01
    “…It regulates water loss and defends against environmental stressors and pathogens. Despite its significance, understanding of the micro-mechanical properties of the cuticle (cuticular membrane; CM) remains limited. …”
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  6. 446

    Transcriptional regulation of suberin and its response to the environment by ZHOU Yue, AN Yongping, MA Rong, WANG Pei

    Published 2024-12-01
    “…Acting as a barrier between the plants and their environment, suberin controls the transport of water and solutes, protecting plants from environmental stresses and pathogenic invasion. This article reviews the key enzymes and transcription factors involved in suberin biosynthesis, and discusses the impact of environmental factors on suberin synthesis and deposition. …”
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  7. 447

    Investigation of new exopolysaccharides produced by strains of donkey milk by Arevik Israyelyan, Tsovinar Balabekyan, Lara Aleksanyan, Inesa Sahakyan, Anna Gasparyan, Flora Тkhruni

    Published 2025-02-01
    “…Results: The antimicrobial activity of the polysaccharide and antimicrobial protein-like fractions of the genus Enterococcus strains depends on its concentration, time of interaction with the test culture, and the species of the pathogenic bacteria. Conclusion: The obtained results were shown that strains isolated from fermented donkey milk that are capable of synthesizing two substances of different nature with high antimicrobial properties during the growth process are promising for further research and application for their use as probiotics and biopreparations in pharmaceuticals. …”
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  8. 448

    Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases by Néstor DelaPaz-Ruíz, Ellen-Wien Augustijn, Mahdi Farnaghi, Sheheen A. Abdulkareem, Raul Zurita Milla

    Published 2025-02-01
    “…To that end, we developed an integrated Agent-Based Model (ABM) that facilitates analysis in space and time at various temporal resolutions, including disease spread, population mobility and wastewater production, while also being sufficiently generic for different types of infectious diseases or pathogens. The integrated model replicates the epidemic curve for COVID-19 and can estimate the daily infections at the household level, enabling the monitoring of the spatial patterns of infection intensity. …”
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  9. 449

    Potency of the Consortium of Pseudomonad fluorescent pf-142 and Bacillus mycoides Isolates Against Bacterial Wilt Disease In-Vitro by Yosua Nathanael Itona Sagala, Endang Triwahyu Prasetyawati, Yenny Wuryandari

    Published 2024-12-01
    “…The variables observed were the symptoms of attack and pathogenicity of R. solanacearum, compatibility and inhibitory rate of the consortium of Pseudomonad fluorescens pf-142 and B. mycoides against R. solanacearum. …”
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  10. 450

    Identification of a comprehensive set of transcriptional regulators involved in the long-term survivability of Escherichia coli in soil by Soma Nakamoto, Ikki Kobayashi, Koichi Watanabe, Takeru Kikuta, Sousuke Imamura, Tomohiro Shimada

    Published 2025-02-01
    “…These transcription factors are often global regulators and conserved among other pathogenic bacterial species. Taken together, we successfully identified a comprehensive set of transcription factors involved in the long-term survival of E. coli in soil. …”
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  11. 451

    Substantiation of application and estimation of efficacy of probiotics at inflammatory bowel diseases by Ye. A. Poluektova, Yu. O. Sidorina, S. Yu. Kuchumova, A. V. Korolev, O. S. Shifrin

    Published 2015-05-01
    “…At patients with IBD the intestinal microbiome have quantitative and qualitative differences from microbiome of healthy patients aside of increase in contents of opportunistic and pathogenic microorganisms. Microbiome changes result in initiation of cascade of pathological immune reactions of the host in related to presence of genetical defects, that, in turn, promotes development of clinical symptoms and morphological changes in intestinal wall. …”
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  12. 452

    Differential Diagnosis of MutYH-Associated Polyposis from Sporadic Colon Polyps by A. S. Tsukanov, V. P. Shubin, A. M. Kuzminov, M. Kh. Toboeva, T. A. Savelyeva, V. N. Kashnikov, Yu. A. Shelygin

    Published 2019-01-01
    “…Mutations in the MutYH gene were not detected in patients with 4–19 polyps (p <0.05). The pathogenic significance of the disease development was established not only for biallelic, but also for monoallelic mutations.Conclusion. …”
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  13. 453

    A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

    Published 2025-01-01
    “…Crustin, a widely-studied antimicrobial peptides (AMPs), has been proven to be involved in mediating innate immune responses against intruding pathogens. In this study, a novel crustin-like gene, Cqcarc1, was characterized from the redclaw crayfish Cherax quadricarinatus. …”
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  14. 454

    Test for Bacterial Content in Soy Sauce and Tomato Sauce at Masomba Market, Palu City by Hasrina

    Published 2022-07-01
    “…For further researchers, it is hoped that they will be able to examine other pathogenic bacteria and check the content of other food additives contained in soy sauce such as preservatives, thickeners.…”
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  15. 455

    Principles of portal hypertension treatment at patients with liver cirrhosis by Ye. A. Fedosina, M. V. Mayevskaya, V. T. Ivashkin

    Published 2012-09-01
    “…As the major part of these states peripheral vasodilation, prescription of vasoconstrictors (first of all — terlipressin) is pathogenically justified and results in arrest of acute bleedings from esophageal VV, and in functional recovery of kidneys at renal failure.…”
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  16. 456

    Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024) by Pengpeng Ji, Meng Ma, Xiaoyue Geng, Jian Zhang

    Published 2025-02-01
    “…In 2024, WHO added multiple multidrug-resistant (MDR) Gram-negative bacteria to the bacteria priority pathogens list, and the continued increase in MDR Gram-negative bacteria poses a serious threat to public health. …”
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  17. 457

    Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury by Zhu Y, Xu G

    Published 2025-02-01
    “…Recent research has therefore focused on the development of targeted therapies aimed at disrupting specific pathogenic signaling cascades within podocytes, resulting in noteworthy advancements. …”
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  18. 458

    Treatment of extrasphincter rectal fistulas with bioplastic substance application by A. M. Kuzminov, Sh. T. Minbayev, V. Yu. Korolik, L. P. Orlova, O. Yu. Fomenko, N. A. Polyakova, A. A. Safoyan, S. M. Khermez

    Published 2012-09-01
    “…Surgical treatment of extrasphincter fistulas of rectum by formation of internal fistulous ostium by bioplastic substance «Collost» is pathogenicly proven. Its application allows to achieve permanent clinical effect, to decrease rate of postoperative morbidity, to reduce terms of rehabilitation of the operated patients.…”
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  19. 459

    Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

    Published 2024-09-01
    “… Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline and behavioral disturbances. The pathogenic characteristics encompass the existence of amyloid plaques outside the cells, neurofibrillary tangles inside the cells, neuroinflammation, oxidative stress, and the loss of synapses. …”
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  20. 460

    Comparison of chemical constituents in Lysimachia species and their antimicrobial activity for extending the shelf life of foods by Li-Li Chen, Shuang Long Yang, Ji-Cun Bao, Wei-You Xie, Zhao-Chan Wang, Nian Shi, Zhao-Jie Wang

    Published 2025-01-01
    “…The KBZZC-05, 21, and 23 inhibited both spoilage organisms and foodborne pathogens (MICs = 2–256 μg/mL) better than potassium sorbate (MIC >256 μg/mL). …”
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