Investigation of Crinum solapurense leaves extract for antidiabetic activity and histopathological evaluation in an in-vivo experimental model by Sunayana Mali, Gaurav Jain, Jyotiram Sawale, Audumbar Mali

“…In the histopathological study, the higher dose of C. solapurense (400.00 mg/kg) showed very significant effects for the regeneration of cells for beta islets of Langerhans on hematoxylin and eosin-stained pancreas cells in dexamethasone-induced diabetic rats. …”
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Caracterización de pacientes con tumores esofágicos atendidos en el Hospital Celestino Hernández Robau (2016-2017) by Lis Soto Riquelme, Jorge Ernesto González García, Dianelys Molina Macías

“…<p><strong>Fundamento</strong>: el cáncer de esófago es una de las neoplasias más agresivas del tubo digestivo, y se asocia a alta morbilidad y mortalidad; similar al cáncer de pulmón, hígado, páncreas y estómago. Su incidencia presenta grandes variaciones geográficas. …”
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Efficacy and safety of neoadjuvant bevacizumab plus chemotherapy in locally advanced gastric cancer patients: a retrospective, comparative study by Bin Yin, Wei Luo

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Initial validation of the clinical significance of the NETest in Japanese gastroenteropancreatic neuroendocrine tumor patients by Hao Zhang, Takahiro Tsuchikawa, Satoshi Takeuchi, Kenji Hirata, Kimitaka Tanaka, Aya Matsui, Yoshitsugu Nakanishi, Toshimichi Asano, Takehiro Noji, Toru Nakamura, Shintaro Takeuchi, Masataka Wada, Satoshi Hirano

“…Among 35 patients (median age: 59 [49–66] years), 27 cases originated from the pancreas and eight from the gastrointestinal tract. …”
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Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa by Tandi E. Matsha, Carmen Pheiffer, Stephen E. Humphries, Junaid Gamieldien, Rajiv T. Erasmus, Andre P. Kengne

“…Our data shows that genes related to the immune system, signal transduction, glucose transport, and pancreas development have altered DNA methylation in subjects with prediabetes and diabetes. …”
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Diagnostic and Prognostic Impact of Progesterone Receptor Immunohistochemistry: A Study Evaluating More Than 16,000 Tumors by Florian Viehweger, Lisa-Marie Tinger, David Dum, Natalia Gorbokon, Anne Menz, Ria Uhlig, Franziska Büscheck, Andreas M. Luebke, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Christoph Fraune, Patrick Lebok, Sören Weidemann, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Rainer Krech, Till Krech, Andreas H. Marx, Ronald Simon, Eike Burandt, Stefan Steurer, Guido Sauter, Sarah Minner, Christian Bernreuther

“…Among the group of nongynecological and nonmammary tumors, particularly high rates of PR positivity were seen in neuroendocrine tumors (54.3%) and neuroendocrine carcinomas (35.7%) of the pancreas. A comparison with clinico-pathological parameters showed that reduced PR immunostaining was significantly associated with adverse histopathological and clinical features in breast carcinoma, endometrioid endometrial carcinoma, and pancreatic neuroendocrine tumors. …”
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An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor by Sanjivini V. Jacob, John D. Reith, Angerika Y. Kojima, William D. Williams, Chen Liu, Lizette Vila Duckworth

“…PET/CT scan revealed abnormal activity in the liver, adrenal gland, and pancreas. MRI of the abdomen demonstrated two 6-7 cm masses in the liver. …”
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Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis by Irena Plahuta, Žan Šarenac, Medeja Golob, Špela Turk, Bojan Ilijevec, Tomislav Magdalenić, Stojan Potrč, Arpad Ivanecz

“…Laparoscopic distal pancreatectomy is a minimally invasive approach for the surgical treatment of neoplasms in the distal pancreas. This study aimed to compare this approach to the open procedure. …”
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Peripartum Severe Acute Pancreatitis with Rare Complications: Case Report and Review of Literature by Syed Muhammad Ali, Nissar Ahmed Shaikh, Zia Aftab, Ejaz Latif, Muhammad Sameer, Muhammad Burhan Khan, Mohannad Al-Tarakji

“…Ultrasound (USG) showed bulky pancreas with gallstones. She was diagnosed as having acute biliary pancreatitis and started to be hydrated and was supplemented with analgesia. …”
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Evaluation of serum amylase and lipase in diagnosed Covid-19 survivors in a North Indian Hospital, Lucknow, India by Nabeela Usmani, Mukhtar Ahmad, Saba Khan, Mohammad Mustufa Khan, Haseeb Ahsan, Sadaf Parveen, Roshan Alam

“…Although it primarily affects the respiratory system, the virus may also target the pancreas. It was suggested that upregulation of angiotensin-converting enzyme II (ACE-II) cell receptors or inflammatory cytokines play a major role in predisposing pancreatic injury in SARS-CoV-2 patients. …”
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International Consensus Diagnostic Criteria for Autoimmune Pancreatitis and Its Japanese Amendment Have Improved Diagnostic Ability over Existing Criteria by Masahiro Maruyama, Takayuki Watanabe, Keita Kanai, Takaya Oguchi, Takashi Muraki, Hideaki Hamano, Norikazu Arakura, Shigeyuki Kawa

“…The recent International Consensus Diagnostic Criteria (ICDC) for autoimmune pancreatitis (AIP) and its Japanese amendment developed by the Japanese Pancreas Society (JPS 2011) may have overcome the drawbacks of earlier criteria and achieved a higher diagnostic ability for AIP. …”
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Intraductal Papillary Neoplasms of the Bile Duct by Masayuki Ohtsuka, Hiroaki Shimizu, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Toshio Tsuyuguchi, Yuji Sakai, Osamu Yokosuka, Masaru Miyazaki

“…Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas. IPNBs display a spectrum of premalignant lesion towards invasive cholangiocarcinoma. …”
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Dysbiosis and extraintestinal cancers by Ruishan He, Pingqian Qi, Linzhen Shu, Yidan Ding, Peng Zeng, Guosheng Wen, Ying Xiong, Huan Deng

“…This review aims to comprehensively summarize the existing evidence that points to the potential role of dysbiosis in the malignant transformation of extraintestinal organs such as the liver, breast, lung, and pancreas. Additionally, we delve into the limitations inherent in current methodologies, particularly the challenges associated with differentiating low loads gut-derived microbiome within tumors from potential sample contamination or symbiotic microorganisms. …”
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Cancer odds among Ohio firefighters: data from the Ohio Cancer Incidence Surveillance System (OCISS) 1996–2019 by Robert Hood, Olorunfemi Adetona, Susan Elizabeth Olivo-Marston, Shashank Singh

“…They had decreased odds of pancreas, lung and bronchus and bladder compared with both police and the general population. …”
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Effects of Splenectomy on Spontaneously Chronic Pancreatitis in aly/aly Mice by Heng-Xiao Wang, Shuang-Qin Yi, Jun Li, Hayato Terayama, Munekazu Naito, Shuichi Hirai, Ning Qu, Nozomi Yi, Masahiro Itoh

“…Histological and immunohistochemical analyses of the pancreas were performed at the ages of 20, 30, and 40 weeks old after operation, respectively. …”
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The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class? by Ricardo Godinho, Cristina Mega, Edite Teixeira-de-Lemos, Eugénia Carvalho, Frederico Teixeira, Rosa Fernandes, Flávio Reis

“…Recent studies have been focusing on the putative ability of DPP-4 inhibitors to preserve pancreas function, in particular due to the inhibition of apoptotic pathways and stimulation of β cell proliferation. …”
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Risk Factors and Medico-Economic Effect of Pancreatic Fistula after Pancreaticoduodenectomy by Renping Huang, Bing Liu, Hua Chen, Xuewei Bai, Rui Kong, Gang Wang, Yongwei Wang, Bei Sun, Yinghui Guan

“…The excessive drinking, soft remnant pancreas, preoperative albumin, and intraoperative blood transfusion are risk factors affecting both PF and CR-PF incidence. …”
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Continuous Quadrupole Magnetic Separation of Islets during Digestion Improves Purified Porcine Islet Viability by Bradley P. Weegman, Venkata Sunil Kumar Sajja, Thomas M. Suszynski, Michael D. Rizzari, William E. Scott III, Jennifer P. Kitzmann, Kate R. Mueller, Thomas R. Hanley, David J. Kennedy, Paul W. Todd, Appakalai N. Balamurugan, Bernhard J. Hering, Klearchos K. Papas

“…Islets in the SPL were preferentially labeled using magnetic microparticles (MMPs) that lodge within the islet microvasculature when infused into the pancreas and were continuously separated from the exocrine tissue by QMS during the collection phase of the digestion process. …”
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Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses by Patrick Nelson, Noah Smith, Stanca Ciupe, Weiping Zou, Gilbert S. Omenn, Massimo Pietropaolo

“…Our model is able to describe changes in the ratio of pathogenic T cells and regulatory T cells after the appearance of islet antibodies in the pancreas. Finally, we discuss the robustness of the model and its ability to assist experimentalists in designing studies to test complicated theories about the disease.…”
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miR-375 Promotes Pancreatic Differentiation In Vitro by Affecting Different Target Genes at Different Stages by Zhenyu Lu, Jing Wang, Xu Wang, Zhiying Li, Dan Niu, Min Wang, Jinzhu Xiang, Yongli Yue, Yajuan Xia, Xueling Li

“…Human embryonic stem cells (hESCs) possess the ability to differentiate into insulin-producing cells (IPCs), which can be used to treat type I diabetes. miR-375 is an essential transcriptional regulator in the development and maturation of the pancreas. In this study, we optimized a protocol to differentiate hESCs into IPCs and successfully obtained IPCs. …”
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