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Statistical analysis on avoidance of palindromic sequences in genomes of microorganisms
Published 2003-12-01Get full text
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Świat na wspak. „Przygoda człowieka poczciwego” Franciszki i Stefana Themersonów jako film-walizka
Published 2010-06-01Subjects: Get full text
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Genome-Wide Identification and Classification of MicroRNAs Derived from Repetitive Elements
Published 2014-12-01Subjects: Get full text
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Nam et expectat et attendit et meminit – Dimensionalität von Zeit und Zeiterfahrung in der Fuge cis-Moll BWV 849
Published 2008-01-01Subjects: Get full text
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Over/exposure in The Atlas by William T. Vollmann
Published 2013-12-01“…This paper examines the way Vollmann uses photography and text in a palindrome composition in The Atlas, among other figures of symmetry, to frame the other as oneself.…”
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A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9
Published 2025-02-01“…Here, a series of iteratively improved cytosine base editors (CBEs) are constructed using the FrCas9 nickase (FrCas9n) with the unique PAM palindromic structure (NNTA) to alleviate these challenges. …”
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A bacteriophage model based on CRISPR/Cas immune system in a chemostat
Published 2017-09-01“…Clustered regularly interspaced short palindromic repeats (CRISPRs) along with Cas proteins are a widespread immune system across bacteria and archaea. …”
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Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration
Published 2024-07-01“…Aim: Evaluate the selective cytotoxic effect of the palindromic sequence RWQWRWQWR and its analogues obtained by replacement of L-amino acids by D-amino acids or the functionalization by adding the RGD (integrin ligand motif) to the peptide. …”
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Genetic Improvement of rice Grain size Using the CRISPR/Cas9 System
Published 2025-01-01“…The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene editing system is a convenient tool for modifying genes. …”
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Targeting EBV Episome for Anti-Cancer Therapy: Emerging Strategies and Challenges
Published 2025-01-01“…We also highlight emerging technologies, such as clustered regularly interspersed short palindromic repeat (CRISPR)-based gene editing or activation, which offer promising avenues for selective targeting of the EBV episome for anti-cancer therapy. …”
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Exploiting CRISPR/Cas system in controlling antibiotic resistance of bacteria
Published 2024-07-01“…Clustered Regularly interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated proteins (Cas) protect archaebacteria and eubacteria from potentially harmful foreign DNA such as plasmids, transposable elements, and phages. …”
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CRISPR/Cas9-Based Protocol for Precise Genome Editing in Induced Pluripotent Stem Cells
Published 2024-12-01“…The advent of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based genome editing has marked a significant advancement in genetic engineering technology. …”
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Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy
Published 2018-01-01“…New advances in the field of genome editing using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas) have provided an accurate and efficient way to edit the human genome and represent an appealing alternative for treating IRDs. …”
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CRISPR/Cas Enzyme Catalysis in Liquid–Liquid Phase‐Separated Systems
Published 2025-01-01“…Abstract The clustered regularly interspaced palindromic repeats (CRISPR) /CRISPR‐associated proteins (Cas) system is the immune system in bacteria and archaea and has been extensively applied as a critical tool in bioengineering. …”
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Evolution of CpG-islands by means of tandem duplications
Published 2017-02-01“…The degenerate nature of CpG-island (elevated CG composition) implies an increase in the probability of tandem repeats and palindromes within CpG- island. This work is devoted to the identification of tandem duplications of complete CpG-islands, i. e. considering mega monomers of size 400–5 000 bp, in the human genome. …”
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The Proviral Reservoirs of Human Immunodeficiency Virus (HIV) Infection
Published 2024-12-01“…Uncovering the causes of this phenomenon will bring humanity closer to curing HIV infection, potential approaches to which include stem cell transplantation, clustered regularly interspaced short palindromic repeats (CRISPR)/cas9, “Shock and kill”, “Block and lock”, and the application of broad-spectrum neutralizing antibodies (bNAbs).…”
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Structural basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex
Published 2025-02-01“…Abstract Type I-E CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated proteins) system is one of the most extensively studied RNA-guided adaptive immune systems in prokaryotes, providing defense against foreign genetic elements. …”
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A combined recombinase polymerase amplification CRISPR/Cas12a assay for detection of Fusarium oxysporum f. sp. cubense tropical race 4
Published 2025-01-01“…In this study, a single-tube detection technique was developed by combining recombinase polymerase amplification (RPA) and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a technology (RPA-Cas12a) for detection of Foc TR4. …”
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Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes
Published 2015-01-01“…In this respect, the development of clinically applicable derivatives of the palindromic compound 1,6-bis(phosphocholine)-hexane (1,6-bis PC) should be a major focus of future CRP research.…”
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