Bernese Periacetabular Osteotomy in a Hip Extra-Articular Resection Followed by Reconstruction Using an Extracorporeal Irradiated Acetabulum Autograft with Megaprosthesis, for Proximal Femur Osteosarcoma in a Pediatric Patient by Victor Barro, Roberto Velez, Daniel Pacha, Jordi Giralt, Isabel Roca, Marius Aguirre

“…Osteosarcoma is the most common primary malignant tumour of bone. …”
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Malignant phyllodes tumors with sarcomatous components: A histopathologic and molecular study by Ting Lei, Yunjie Song, Zhiyi Shen, Yongqiang Shi, Cunyan Xia, Xu Deng, Wenyue Da, Yan Peng, Qing Li

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Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR by Pui Yeng Lam, Natacha Omer, Josh K. M. Wong, Cui Tu, Louisa Alim, Gustavo R. Rossi, Maria Victorova, Hannah Tompkins, Cheng‐Yu Lin, Ahmed M. Mehdi, Amos Choo, Melissa R. Elliott, Elaina Coleborn, Jane Sun, Timothy Mercer, Orazio Vittorio, Lachlan J. Dobson, Alexander D. McLellan, Andrew Brooks, Zewen Kelvin Tuong, Seth W. Cheetham, Wayne Nicholls, Fernando Souza‐Fonseca‐Guimaraes

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Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS by Chaoyi Yin, Kede Chi, Zhiqing Chen, Shabin Zhuang, Yongsheng Ye, Binshan Zhang, Cailiang Cai

Subjects: “…osteosarcoma…”
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Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex by Lu Ma, Hua Liu, Yichun Ju, Kai Chen, Yi Yang, Zhichao Zhou, Zhenqin Zhang, Zheng Cai

“…Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility. …”
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Targeting Glutathione-S Transferase Enzymes in Musculoskeletal Sarcomas: A Promising Therapeutic Strategy by Michela Pasello, Maria Cristina Manara, Francesca Michelacci, Marilù Fanelli, Claudia Maria Hattinger, Giordano Nicoletti, Lorena Landuzzi, Pier Luigi Lollini, Annamaria Caccuri, Piero Picci, Katia Scotlandi, Massimo Serra

“…Recent studies have indicated that targeting glutathione-S-transferase (GST) isoenzymes may be a promising novel strategy to improve the efficacy of conventional chemotherapy in the three most common musculoskeletal tumours: osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. …”
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Concurrent Cemento-Osseous Dysplasia and Osteogenic Sarcoma: Report of Two Cases by A. A. Olusanya, B. F. Adeyemi, A. O. Adisa

“…The two patients were diagnosed of mandible osteosarcoma occurring concurrently with bilateral mandibular focal cemento-osseous dysplasia. …”
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Multicentric Giant Cell Tumor of Bone: Synchronous and Metachronous Presentation by Reiner Wirbel, Frank Blümler, Dirk Lommel, Guido Syré, Veit Krenn

“…The patient has an eighteen-year history of a healed osteosarcoma of the right tibia that was treated with chemotherapy, resection, and allograft reconstruction. …”
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Diagnostic challenge in chondromyxoid fibroma clinically mimicking neuroma by Aleksandra Izabela Masłowska, Julia Sołek, Paulina Jagodzińska-Mucha, Marcin Braun, Hanna Romańska

“…Furthermore, this report illustrates an atypical diagnostic journey, from an initial neuroma through a low-grade osteosarcoma, to a final benign chondromyxoid fibroma.…”
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An In Vitro Study of the Effects of Methotrexate Loaded Biocomposite Beads on MG63 Osteoblast Cells by A. E. Malash, A. A. Al-esnawy, Khairy T. Ereiba, Ahmed M. Bakr, A. S. Abdraboh

“…A cytotoxicity study of the methotrexate was performed by a human osteosarcoma (MG-63) cell line. Results indicated that the formation of a hydroxyapatite layer on the bead’s surface confirmed its biological activity. …”
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Exploiting somatic oncogenic driver alterations in a patient with Li-Fraumeni syndrome– paving the path towards precision medicine: a case report by Carolin Seeling, Sonja Dahlum, Ralf Marienfeld, Vera Jan, Brigitte Rack, Uwe Gerstenmaier, Ambros J. Beer, Regine Mayer-Steinacker, Wolfgang Thaiss, Thomas F. E. Barth, Thomas Seufferlein, Nadine T. Gaisa, Stephan Stilgenbauer, Wolfgang Janni, Reiner Siebert, Hartmut Döhner, Verena I. Gaidzik

“…Case presentation We present the case of a woman with breast cancer and subsequent osteosarcoma, both treated with surgery and chemotherapy. …”
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Biphasic Malignant Pleural Mesothelioma Masquerading as a Primary Skeletal Tumor by James Benjamin Gleason, Basheer Tashtoush, Maria Julia Diacovo

“…We herein report a case of a 41-year-old man who presented with chest pain and had a chest computed tomography (CT) scan suggestive of a primary skeletal tumor originating from the ribs (chondrosarcoma or osteosarcoma), with no history of asbestos exposure. …”
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Intramedullary Chondrosarcoma of Proximal Humerus by Pratiksha Yadav, Dolly Thakkar, S. S. Thind

“…Primary chondrosarcoma is the third most frequent primary malignancy of bone after myeloma and osteosarcoma. It is ranging from slow growing nonmetastasising lesions to highly aggressive lesions. …”
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Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers by Mei Zhang, Veronique Roche, Victor Sandoval, Claire Wolford, Zachary Senders, Julian Anthony Kim, Susan Pereira Ribeiro, Alex Yicheng Huang, Rafick-Pierre Sekaly, Joshua Lyons

“…This engagement significantly impacts the biological function of tumor-associated inflammatory monocytes (TAIMs) in osteosarcoma, advanced melanoma, and PDAC backgrounds. …”
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Involvement of HMGB1 in Resistance to Tumor Vessel-Targeted, Monoclonal Antibody-Based Immunotherapy by Vito Pistoia, Annalisa Pezzolo

“…HMGB1-induced autophagy promotes tumor resistance to chemotherapy, as shown in different models of malignancy, for example, osteosarcoma, leukemia, and gastric cancer. To the best of our knowledge, there is virtually no information on the relationships between HMGB1 and resistance to immunotherapy. …”
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Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals by Gerardo Claudio Glikin, Liliana María Elena Finocchiaro

“…A variety of tumors such as canine melanoma, soft tissue sarcomas, osteosarcoma and lymphoma, feline fibrosarcoma, and equine melanoma were subjected to different treatment approaches. …”
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Research progress of circRNAs in bone-related diseases by Xianming Hua, Lingfeng Yu, Hao Zhu, Yan Zhu, Gentao Fan, Guangxin Zhou, Guangxin Zhou, Guangxin Zhou

“…Studies have shown that circRNAs play an irreplaceable role in the pathogenesis, disease progression, diagnosis, and targeted therapy of motor system tumors (osteosarcoma), metabolic diseases (osteoporosis), and degenerative diseases (osteonecrosis of the femoral head, osteoarthritis, intervertebral disc degeneration). …”
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Maternal Mortality: 10 Year Experience of a Tertiary Center in Turkey by Erdem Fadiloglu, Canan Unal, Atakan Tanacan, Serpil Ocal, Banu Kilicaslan, Seda Banu Akinci, Arzu Topeli, M. Sinan Beksac

“…Maternal mortality causes were cardiopulmonary failure secondary to veno-occlusive disease, septic shock secondary to osteosarcoma, pulmonary thromboembolism secondary to metastatic breast cancer, septic shock secondary to cholecystitis, and postpartum hemorrhage secondary to Niemann–Pick disease. …”
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Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab by Cory Julian Broehm, Erika L. Garbrecht, Jeff Wood, Therese Bocklage

“…We report two cases of sarcomatous transformation of GCT to osteosarcoma in patients receiving denosumab. One was a 59-year-old male with a 12-year history of GCT and multiple recurrences taking denosumab for 2.5 years. …”
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Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma by Mario Carbone, Francesco Della Ferrera, Lucio Carbone, Gaia Gatti, Marco Carrozzo

“…Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, and mandibular metastasis of primary carcinoma of breast, lung, thyroid, kidney, prostate, and nasopharynx. …”
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