C-Reactive Protein Knockout Attenuates Temporomandibular Joint Inflammation in Rats by Yao He, Mengjiao Zhou, Zixiang Jian, Lingli Fang, Lan Huang, Jinlin Song

“…C-reactive protein (CRP), a biomarker of inflammation, is highly expressed in osteoarthritis- (OA-) related diseases, but its exact role remains unknown. …”
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Prevalence of major depression in elder people attending a national hospital in Lima by Magnolia Matutti Rosas, Orlando Tipismana Neyra

“…Uninsured comorbid with depression show DM, hypertension, osteoarthritis, and women age 60-75 It is more frequent than in Group 76 more assured, presents qualitative spectrum same trend groups have depression and comorbidity (Figure 1, 2, 3.4) Conclusion: Both groups have depression and comorbidity, even though it is depth analysis needed to confirm data with others.…”
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The Potential of Curcumin in Treatment of Spinal Cord Injury by Raghavendra Sanivarapu, Vijayalakshmi Vallabhaneni, Vivek Verma

“…Because curcumin has shown improvements from current standards of care in other diseases with few true treatment options (e.g., osteoarthritis), there is immense potential for this compound in treating SCI. …”
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Articular Cartilage Gene Expression after Coxofemoral Joint Luxation in the Dog by Korakot Nganvongpanit, Waranee Pradit, Siriwadee Chomdej

“…In conclusion, a delay in joint reduction may increase the chances of development of osteoarthritis.…”
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Neck of Femur Fracture in a Patient with a Chronic Osteomyelitis of the Ipsilateral Foot by Anne-Carolin Döring, Anne J. H. Vochteloo, Kees van Doorn, Rianne M. H. A. Huis in ’t Veld, Anil Peters

“…Only a few cases of total hip arthroplasty in amputees have been published, but the indication for surgery was mainly traumatic or advanced osteoarthritis. Treating patients with this type of comorbidities is challenging; therapeutic dilemmas can be major. …”
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Moving from an “anti-aging” paradigm toward the concept of “disease-free aging”: the role of senolytics in modern medicine by Ivan Aprahamian, Andréia Pain, Virgílio Garcia Moreira

“…These cells are closely related to the biological aging process and, most importantly, to age-associated diseases, such as osteoporosis and osteoarthritis. Senolytics are a new drug class that kills senescent cells by targeting senescent cell anti-apoptotic pathways (SCAPs), which are biological systems that avoid cellulardestruction and host innate defenses. …”
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An Unusual Presentation of Insert Dislocation and MCL Rupture in Unicompartmental Knee Replacement with 2 Years Postoperative Results: Does It Functional? by Ali Asma, Mehmet Erduran, Musa Eymir

“…Firstly, 63-year-old woman was treated with UKR due to anteromedial knee osteoarthritis of the right knee joint. 1 year after UKR surgery, she suffered from MCL rupture and mobile-bearing dislocation because of falls while getting on a public bus, and therefore, secondly, she was operated with MCL primary repair and mobile-bearing change and followed up for 2 years. …”
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Propionibacterium acnes: A Treatable Cause of Constrictive Pericarditis by Daniel Cruz, Haitham Ahmed, Yousuf Gandapur, M. Roselle Abraham

“…The patient was a 61-year-old male with history of osteoarthritis of the knee. He received an intra-articular steroid injection in July 2013. …”
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Promoting Articular Cartilage Regeneration through Microenvironmental Regulation by Kai Liu, Bingjun Zhang, Xiaoling Zhang

“…In recent years, as the aging population continues to grow, osteoarthritis (OA) has emerged as a leading cause of disability, with its incidence rising annually. …”
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Prevalence of Temporomandibular Joint Osteoarthritic Changes Using Cone-beam Computed Tomography in South Indian Population by S. Pattugayathri, B. G. Harshavardhan, V. Poongodi, K. Saraswathi Gopal

“…Introduction: Osteoarthritis of temporomandibular joint (TMJ) is a chronic degenerative joint disease characterized by synovitis, cartilage destruction, and subchondral bone remodeling and it is an age-related disorder. …”
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Research progress of circRNAs in bone-related diseases by Xianming Hua, Lingfeng Yu, Hao Zhu, Yan Zhu, Gentao Fan, Guangxin Zhou, Guangxin Zhou, Guangxin Zhou

“…Studies have shown that circRNAs play an irreplaceable role in the pathogenesis, disease progression, diagnosis, and targeted therapy of motor system tumors (osteosarcoma), metabolic diseases (osteoporosis), and degenerative diseases (osteonecrosis of the femoral head, osteoarthritis, intervertebral disc degeneration). This review summarizes the advancements in circRNA detection techniques and the research progress of circRNAs in orthopedic diseases.…”
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Glutathione: A Key Regulator of Extracellular Matrix and Cell Death in Intervertebral Disc Degeneration by Fudong Li, Shaofei Li, Yangyang Shi, Feng Lin, Lining Rui, Jiangang Shi, Kaiqiang Sun

“…In addition, it was reported that the level of GSH widely participates in apoptosis, autophagy, ferroptosis, and oxidative stress in many diseases including osteoarthritis and IVDD. Therefore, we summarized the effects of GSH on ECM metabolism and cells’ functions during IVDD. …”
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Pseudoaneurysm of the Perforating Peroneal Artery following Ankle Arthroscopy by Ichiro Tonogai, Eiki Fujimoto, Koichi Sairyo

“…The patient presented with a pseudoaneurysm of the perforating peroneal artery following ankle arthroscopy for traumatic osteoarthritis associated with nonunion of the medial malleolus. …”
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DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone by Lei Ding, Joseph A. Buckwalter, James A. Martin

“…To investigate whether endogenous damage-associated molecular patterns (DAMPs) or alarmins originated from mitochondria or nucleus stimulates inflammatory response in articular chondrocytes to cause chondrolysis which leads to cartilage degradation featured in posttraumatic osteoarthritis (PTOA). Materials. Primary cultures of bovine or human chondrocytes isolated from cartilage of weight-bearing joints. …”
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Herbal remedies as a potential alternative therapy for arthritis by Disha Trivedi, Riya Jayapal Roja, Eva Künnemann

“…In this review, we show the pathology of osteoarthritis and rheumatoid arthritis, a disease condition affecting millions of people worldwide and we describe herbal materials that are used for arthritis treatment. …”
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Fracture of the Femoral Component Caused by Insufficient Crimping after Modern Unicompartmental Knee Arthroplasty by Yoichi Ishibashi, Tasuku Mashiba, Masaki Mori, Tetsuji Yamamoto

“…A 69-year-old man underwent medial unicompartmental knee arthroplasty for right medial knee osteoarthritis. His early postoperative course was good; however, the 1-year postoperative radiograph showed an apparent radiolucent line around the femoral component, and he occasionally had right knee pain. …”
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Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors by Gun Woo Lee, Tae-Hun Kim, Jung-Hwan Son

“…This paper presents a case of 72-year-old man with primary C. guilliermondii infection of knee joint without predisposing factors and previous traumatic procedures, who was misdiagnosed with advanced degenerative osteoarthritis. Our case is the second case of primary C. guilliermondii arthritis of knee to be reported in the English-language literature and the first to be successfully treated with total knee arthroplasty following IV amphotericin B and oral fluconazole. …”
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Lipoma Arborescens of the Knee: Report of Three Cases and Review of the Literature by Ioannis Tsifountoudis, Dimitrios Kapoutsis, Anastasios-Nektarios Tzavellas, Ioannis Kalaitzoglou, Apostolos Tsikes, George Gkouvas

“…We report three cases of lipoma arborescens affecting the knee, the first in a young male without previous history of arthritis or trauma, the second in a 58-year-old male associated with osteoarthritis, and the final in a 44-year-old male diagnosed with psoriatic arthritis, which cover the entire pathologic spectrum of this unusual entity. …”
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Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics by John Burke, Ravindra Kolhe, Monte Hunter, Carlos Isales, Mark Hamrick, Sadanand Fulzele

“…If exosomes could be extracted from stem cells in an efficient manner and packaged with particular regenerative products, then diseases such as rheumatoid arthritis, osteoarthritis, bone fractures, and other maladies could be treated with cell-free regenerative medicine via exosomes. …”
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Is End-Stage Ankle Arthrosis Best Managed with Total Ankle Replacement or Arthrodesis? A Systematic Review by Robert W. Jordan, Gurdip S. Chahal, Anna Chapman

“…Introduction. End-stage ankle osteoarthritis is a debilitating condition. Traditionally, ankle arthrodesis (AA) has been the surgical intervention of choice but the emergence of total ankle replacement (TAR) has challenged this concept. …”
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