Increased Mortality After Lower Extremity Amputation in a Danish Nationwide Cohort: The Mediating Role of Postoperative Complications by Brix ATH, Petersen TG, Nymark T, Schmal H, Lindberg-Larsen M, Rubin KH

“…Anna Trier Heiberg Brix,1,2 Tanja Gram Petersen,3 Tine Nymark,1,2 Hagen Schmal,1,4 Martin Lindberg-Larsen,1,2 Katrine Hass Rubin2,3 1Department of Orthopedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark; 2Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 3Research Unit OPEN, Odense University Hospital and University of Southern Denmark, Odense, Denmark; 4Department of Orthopedics and Traumatology, University Medical Center Freiburg, Freiburg, GermanyCorrespondence: Anna Trier Heiberg Brix, Department of Orthopedic Surgery and Traumatology, Odense University Hospital, J. …”
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Prepatellar Bursal Infection Caused by Mycobacterium tuberculosis with an In Situ Total Knee Arthroplasty: A Case Report and Comprehensive Literature Review by Abdulrahman D. Algarni

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Sharing reliable information worldwide: healthcare strategies based on artificial intelligence need external validation. Position paper by F. Pennestrì, F. Cabitza, N. Picerno, G. Banfi

“…Abstract Training machine learning models using data from severe COVID-19 patients admitted to a central hospital, where entire wards are specifically dedicated to COVID-19, may yield predictions that differ significantly from those generated using data collected from patients admitted to a high-volume specialized hospital for orthopedic surgery, where COVID-19 is only a secondary diagnosis. …”
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Editorial: New insights into the relationship between endocrine disorders and dental diseases by Chaofan Zhang, Chaofan Zhang, Chaofan Zhang, Chaofan Zhang, Shan Jiang, Nianye Zheng, Yunzhi Lin, Yunzhi Lin

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Bladder Cancer Invading the Prostate and Penis and Multiple Bone Metastases Showing Significant Improvement after a Short-Term Pembrolizumab Therapy following Radiation and Gemcita... by Kyohei Ishida, Akira Ogose, Gen Kawaguchi, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama

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Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

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Healthcare Utilization, Costs of Care, and Mortality Among Patients With Spinal Muscular Atrophy by Hiangkiat Tan, Tao Gu, Er Chen, Rajeshwari Punekar, Perry B. Shieh

“…Uses of orthotics/orthoses and orthopedic surgery were frequent: 54.5% and 22.7% childhood group; 27.0% and 38.5% late-onset group. …”
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KL-6 Mucin as Serum Tumor Marker of Metastatic Renal Cancer: A Case Report by Kyohei Ishida, Go Hasegawa, Toshinori Takada, Akira Ogose, Gen Kawaguchi, Yohei Ikeda, Hiroki Nishiyama, Noboru Hara, Tsutomu Nishiyama

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A Case Report of a Subdural Hematoma following Spinal Epidural prior to a Total Knee Arthroplasty by Brian J. Carlson, David G. Deckey, Henry D. Clarke, Joshua S. Bingham

“…This case report adds to current literature on management of a subdural hematoma following total knee arthroplasty and is particularly important as joint replacement moves into outpatient surgery centers where the orthopedic surgery team becomes the sole patient contact point. …”
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First Description of a Primitive Neuroectodermal Tumor Arising in the Nose by Habib Rizk, Aline Khazzaka, Amer Sebaaly, Maguy Cherfan, Roland Tomb, Riad Sarkis

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Metatarsal Transfer for Atypical Phenotype of Foot Polydactyly: A Case Report by Yasufumi Makiuchi, Izumi Ban, Yuji Kuroyanagi, Kiyonori Harii

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Optimal suturing techniques in patch-bridging reconstruction for massive rotator cuff tears: A finite element analysis by Yuting Zhong, Chengxuan Yu, Sijia Feng, Han Gao, Luyi Sun, Yunxia Li, Shiyi Chen, Jun Chen

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B7-H3 CAR-T cell therapy combined with irradiation is effective in targeting bulk and radiation-resistant chordoma cancer cells by Kun Wang, Gianpietro Dotti, Soldano Ferrone, Yufeng Wang, Yin P Hung, Tao Ma, Giulia Cattaneo, Xinhui Wang, David O Osei-Hwedieh, Tara A Walhart, Joseph H Schwab

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Effect of providing at-home opioid disposal kits at discharge after an orthopaedic surgery by Daniel Lee, M Kit Delgado, Zarina Ali, Anish Agarwal, Eric Shan, Ruiying Xiong, Michael Katzman

“…In this study, we assess the impact of opioid disposal kits on disposal rates after orthopedic surgery. In a difference-in-differences study of 1,321 eligible patients, disposal kits were associated with a 10.6 percentage point increase (95% CI: -3.5% to 24.7%) in disposal rates as well as a 10.5 percentage point increase (95% CI: 0.2% to 20.9%) in the fraction of opioids disposed. …”
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Hedgehog signaling directs cell differentiation and plays a critical role in tendon enthesis healing by Fei Fang, Matthew Casserly, Julia Robbins, Stavros Thomopoulos

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Evaluating Hand Function in Clients with Trigger Finger by Danit Langer, Adina Maeir, Michael Michailevich, Shai Luria

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Case Study: Chronic Recurrent Multifocal Osteomyelitis in the Femoral Diaphysis of a Young Female by Jeffrey S. Quon, Anne K. Dzus, David A. Leswick

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Modulation of the Wound Healing through Noncoding RNA Interplay and GSK-3β/NF-κB Signaling Interaction by Xianyi Wang, Wanqiu Li, Shengdi Lu, Zhongliang Ma

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Treatment of Digital Ischemia with Liposomal Bupivacaine by José Raul Soberón, Scott F. Duncan, W. Charles Sternbergh

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Progress in Clinical Diagnosis and Management of Short Stature in Ehlers-Danlos Syndromes by XU Kexin, LI Guozhuang, WU Zhihong, ZHANG Jianguo, DISCO(Deciphering Disorders Involving Scoliosis & Comorbidities) Study Group, WU Nan

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