In Vivo Bioluminescence Imaging Validation of a Human Biopsy–Derived Orthotopic Mouse Model of Glioblastoma Multiforme by Monika A. Jarzabek, Peter C. Huszthy, Kai O. Skaftnesmo, Emmet McCormack, Patrick Dicker, Jochen H.M. Prehn, Rolf Bjerkvig, Annette T. Byrne

“…The model may thus be routinely used for the assessment of novel anti-GBM therapeutic approaches implementing well-established and cost-effective optical imaging strategies.…”
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In Vivo Bioluminescence Imaging of Transplanted Mesenchymal Stem Cells as a Potential Source for Pancreatic Regeneration by Song Lee, Hyewon Youn, Taemoon Chung, Do Won Hwang, So Won Oh, Keon Wook Kang, June-Key Chung, Dong Soo Lee

“…Although insulin secretion was not observed in MSCs, transplanted MSCs facilitate the injured pancreas to recover its function. In vivo optical imaging of transplanted MSCs using a highly sensitive luciferase reporter enables the assessment of MSC transplantation efficiency in a PPx mouse model.…”
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Photoelectrochemical-Type Photodetectors Based on Ball Milling InSe for Underwater Optoelectronic Devices by Yi Xu, Junxin Zhou, Dongyue Tian, Zhendong Fu, Yuewu Huang, Wei Feng

“…Furthermore, the InSe PEC PDs successfully demonstrated prototype application in wireless underwater optical communication and optical imaging. These results demonstrate that M-InSe holds good application prospects in underwater optoelectronic devices.…”
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Three-Dimensional in Vivo Imaging of Green Fluorescent Protein-Expressing T Cells in Mice with Noncontact Fluorescence Molecular Tomography by Anikitos Garofalakis, Giannis Zacharakis, Heiko Meyer, Eleftherios N. Economou, Clio Mamalaki, Joseph Papamatheakis, Dimitris Kioussis, Vasilis Ntziachristos, Jorge Ripoll

“…Given that optical tomography is capable of quantitatively imaging the distribution of several important chromophores and fluorophores in vivo, there has been a great deal of interest in developing optical imaging systems with increased numbers of measurements under optimal experimental conditions. …”
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Gram-Negative Bacterial Infection in Thigh Abscess Can Migrate to Distant Burn Depending on Burn Depth by Victoria Hamrahi, Michael R. Hamblin, Walter Jung, John B. Benjamin, Kasie W. Paul, Alan J. Fischman, Ronald G. Tompkins, Edward A. Carter

“…We used Gram-negative bacteria (Pseudomonas aeruginosa and Proteus mirabilis) that were genetically engineered to be bioluminescent, which allowed for noninvasive, sequential optical imaging of the extent and severity of the infection. …”
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A Teacher-Learning-Based Optimization Approach for Blur Detection in Defocused Images by Sana Munir Khan, Muhammad Tariq Mahmood

“…Defocus blur is often encountered in images taken with optical imaging equipment. It might be unwanted, but it might also be a deliberate artistic effect, which means it might help how we see the scenario in an image. …”
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Effect of Localized Mechanical Indentation on Skin Water Content Evaluated Using OCT by Abhijit A. Gurjarpadhye, William C. Vogt, Yajing Liu, Christopher G. Rylander

“…The highly disordered refractive index distribution in skin causes multiple scattering of incident light and limits optical imaging and therapeutic depth. We hypothesize that localized mechanical compression reduces scattering by expulsing unbound water from the dermal collagen matrix, increasing protein concentration and decreasing the number of index mismatch interfaces between tissue constituents. …”
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Visualizing Head and Neck Tumors in Vivo Using Near-Infrared Fluorescent Transferrin Conjugate by Liang Shan, Yubin Hao, Songping Wang, Alexandru Korotcov, Renshu Zhang, Tongxin Wang, Joseph Califano, Xinbin Gu, Rajagopalan Sridhar, Zaver M. Bhujwalla, Paul C. Wang

“…Our results indicate that TfR is a promising target and that Tf NIR -based optical imaging is potentially useful for noninvasive detection of early HNSCC in the clinic.…”
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Nonlinear Optics in Two-Dimensional Magnetic Materials: Advancements and Opportunities by Ziqian Xin, Bingyuan Xue, Wenbo Chang, Xinping Zhang, Jia Shi

“…This paper outlines the principles of nonlinear optics and the magnetic structures of 2D materials, reviews recent progress in nonlinear optical studies, including magnetic structure detection and nonlinear optical imaging, and highlights their role in probing magnetic properties by combining second harmonic generation (SHG) and multispectral integration. …”
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High-Power, Computer-Controlled, Light-Emitting Diode–Based Light Sources for Fluorescence Imaging and Image-Guided Surgery by Sylvain Gioux, Vida Kianzad, Razvan Ciocan, Sunil Gupta, Rafiou Oketokoun, John V. Frangioni

“…Optical imaging requires appropriate light sources. For image-guided surgery, in particular fluorescence-guided surgery, a high fluence rate, a long working distance, computer control, and precise control of wavelength are required. …”
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Permeation Peptide Conjugates for In Vivo Molecular Imaging Applications by Kristin E. Bullok, Seth T. Gammon, Stefania Violini, Andrew M. Prantner, Victor M. Villalobos, Vijay Sharma, David Piwnica-Worms

“…Membrane permeant peptides based on the HIV-1 Tat basic domain sequence, GRKKRRQRRR, labeled with fluorophores and fluorescent proteins for optical imaging or with appropriate peptide-based motifs or macrocycles to chelate metals, such as technetium for nuclear scintigraphy and gadolinium for magnetic resonance imaging, have been synthesized. …”
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In Vivo Method to Monitor Changes in HER2 Expression Using Near-Infrared Fluorescence Imaging by Moinuddin Hassan, Victor Chernomordik, Rafal Zielinski, Yasaman Ardeshirpour, Jacek Capala, Amir Gandjbakhche

“…We used albumin binding domain–fused HER2-specific Affibody molecules, labeled with Alexa Fluor750 dye, to characterize HER2 expression in vivo. Near-infrared optical imaging studies were carried out using mice with subcutaneous HER2-positive tumors. …”
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Monitoring of Biodistribution and Persistence of Conditionally Replicative Adenovirus in a Murine Model of Ovarian Cancer Using Capsid-Incorporated mCherry and Expression of Human... by Igor P. Dmitriev, Elena A. Kashentseva, Kenneth H. Kim, Qiana L. Matthews, Stephanie S. Krieger, Jesse J. Parry, Kim N. Nguyen, Walter J. Akers, Samuel Achilefu, Buck E. Rogers, Ronald D. Alvarez, David T. Curiel

“…Analysis of 64 Cu-CB-TE2A-Y3-TATE biodistribution in mice revealed reduced uptake in tumors injected with the imaging CRAd relative to the replication-incompetent, Ad-expressing SSTR2 but significantly greater uptake compared to the negative CRAd control. Optical imaging demonstrated relative correlation of fluorescent signal with virus replication as determined by viral genome quantification in tumors. …”
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Lipoprotein Nanoplatform for Targeted Delivery of Diagnostic and Therapeutic Agents by Jerry D. Glickson, Sissel Lund-Katz, Rong Zhou, Hoon Choi, I-Wei Chen, Hui Li, Ian Corbin, Anatoliy V. Popov, Weiguo Cao, Liping Song, Chenze Qi, Diane Marotta, David S. Nelson, Juan Chen, Britton Chance, Gang Zheng

“…Core and surface loading of LDL have been used for delivery of optical imaging agents to tumor cells in vivo and in culture. …”
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Dual-Modality Monitoring of Tumor Response to Cyclophosphamide Therapy in Mice with Bioluminescence Imaging and Small-Animal Positron Emission Tomography by Xibo Ma, Zhaofei Liu, Xin Yang, Qiujuan Gao, Shouping Zhu, Chenghu Qin, Kai Liu, Bo Zhang, Dong Han, Fan Wang, Jie Tian

“…A good linear correlation was found between the tumor sizes measured by caliper and the BLI signals determined by optical imaging ( R 2 = .9216). 18 F-FDG imaging revealed a significant uptake reduction in the tumors of the CTX-treated group compared to that in the saline control group (5.30 ± 1.97 vs 3.00 ± 2.11% ID/g) on day 16 after CTX treatment. …”
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Creation of a stable vector vortex beam with dual fractional orbital angular momentum by Lingyu Wang, Guanxue Wang, Xiangmei Dong, Xiumin Gao, Songlin Zhuang

“…This work not only enriches the types of vortex beams but also provides a novel optical tool, potentially transformative for applications in optical communications, optical manipulation, and optical imaging.…”
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Enhancement of Signal‐to‐Background Ratio in Molecular Vibrational Signal Extraction by Stimulated Emission Depletion Mechanism by Ge Wang, Lizhen Chen, Qiuqiang Zhan, Guangyou Fang, Yisen Wang

“…STED is the mechanism commonly employed in optical imaging; however, its application should not be confined solely to this field. …”
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Microimaging Characterization of a B16-F10 Melanoma Metastasis Mouse Model by Christopher T. Winkelmann, Said Daibes Figueroa, Tammy L. Rold, Wynn A. Volkert, Timothy J. Hoffman

“…Metastatic mouse models of melanoma have been characterized by gross necropsy examination, histopathology, and optical imaging. To determine if the time progression, extent, and metabolism of melanoma metastases could be monitored noninvasively, serial micro-CT and small-animal PET imaging studies were performed by using a mouse model of melanoma. …”
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Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo by Yasaman Ardeshirpour, Amir H. Gandjbakhche, Laleh Najafizadeh

“…In vivo optical imaging is being conducted in a variety of medical applications, including optical breast cancer imaging, functional brain imaging, endoscopy, exercise medicine, and monitoring the photodynamic therapy and progress of neoadjuvant chemotherapy. …”
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Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography by Michael Ghijsen, Yuting Lin, Mitchell Hsing, Orhan Nalcioglu, Gultekin Gulsen

“…Diffuse Optical Tomography (DOT) is an optical imaging modality that has various clinical applications. …”
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