Qualitative Simulation of Photon Transport in Free Space Based on Monte Carlo Method and Its Parallel Implementation by Xueli Chen, Xinbo Gao, Xiaochao Qu, Duofang Chen, Bin Ma, Lin Wang, Kuan Peng, Jimin Liang, Jie Tian

“…During the past decade, Monte Carlo method has obtained wide applications in optical imaging to simulate photon transport process inside tissues. …”
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Annexin V Imaging Detects Diabetes-Accelerated Apoptosis and Monitors the Efficacy of Benfotiamine Treatment in Ischemic Limbs of Mice by Kyung-Ho Jung, Jin Hee Lee, Jin Won Park, Jin Young Paik, Cung Hoa Thien Quach, Eun Jeong Lee, Kyung-Han Lee

“…AnxV-conjugated fluorescent streptavidin probes were intravenously injected, and optical imaging was performed. Tissue apoptosis was quantified by histochemistry and Western blotting. …”
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Dynamic Analysis of the Blood-Brain Barrier Disruption in Experimental Stroke Using Time Domain in Vivo Fluorescence Imaging by Abedelnasser Abulrob, Eric Brunette, Jacqueline Slinn, Ewa Baumann, Danica Stanimirovic

“…The aim of this study was (a) to establish novel in vivo optical imaging methods for longitudinal assessment of the BBB disruption and (b) to assess size selectivity and temporal patterns of the BBB disruption after a transient focal ischemia. …”
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In Vivo Quantitative Measurement of Arthritis Activity Based on Hydrophobically Modified Glycol Chitosan in Inflammatory Arthritis: More Active than Passive Accumulation by Kyeong Soon Park, Jin Hee Kang, Keum Hee Sa, Hee Beom Koo, Hyun Jung Cho, Eon Jeong Nam, In Chan Youn, Kwang Meyung Kim, In San Kim, Ick Chan Kwon, Kui Won Choi, Young Mo Kang

“…These results suggest that optical imaging of arthritis using HGC-Cy5.5 can provide an objective measurement of disease activity and, at the same time, therapeutic responses in rheumatoid arthritis.…”
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In Vivo Bioluminescence Visualization of Antitumor Effects by Human MUC1 Vaccination by Yong Hyun Jeon, Yun Choi, Hyun Joo Kim, Joo Hyun Kang, Chul Woo Kim, Jae Min Jeong, Dong Soo Lee, June-Key Chung

“…After subcutaneously injecting CT26/hMUC1-F luc into mice immunized with pcDNA3-hMUC1, we monitored in vivo tumor growth inhibition using an optical imaging method. The concentration of IFN-γ protein in pcDNA3-hMUC1 was higher than that of the pcDNA3.1 group (2.7 ⩽ 0.08 ng/mL and 1.6 ± 0.07 ng/mL, respectively, p < .001. …”
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High Spatiotemporal Near‐Infrared II Fluorescence Lifetime Imaging for Quantitative Detection of Clinical Tumor Margins by Zhen Chen, Linjian Huang, Duyang Gao, Zhouzhou Bao, Dehong Hu, Wei Zheng, Jing Chen, Jiuling Liao, Hairong Zheng, Zonghai Sheng

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Fluorescent, Plasmonic, and Radiotherapeutic Properties of the Lu–Dendrimer-AuNP–Folate–Bombesin Nanoprobe Located Inside Cancer Cells by Héctor Mendoza-Nava PhD, Guillermina Ferro-Flores PhD, Flor de María Ramírez PhD, Blanca Ocampo-García PhD, Clara Santos-Cuevas PhD, Erika Azorín-Vega PhD, Nallely Jiménez-Mancilla PhD, Myrna Luna-Gutiérrez PhD, Keila Isaac-Olivé PhD

“…The 177 Lu–DenAuNP–folate–bombesin nanoprobe internalized in cancer cells exhibited properties suitable for optical imaging, plasmonic–photothermal therapy, and targeted radiotherapy.…”
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Investigation of an Autofocusing Method for Visible Aerial Cameras Based on Image Processing Techniques by Zhichao Chen, Tao Zhang

“…The system designed in this paper can find the optical imaging focal plane in real-time; as such, this novel design has great potential in practical engineering, especially aerospace applications.…”
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Real-Time Multichannel Imaging Framework for Endoscopy, Catheters, and Fixed Geometry Intraoperative Systems by Rahul A. Sheth, Rabi Upadhyay, Ralph Weissleder, Umar Mahmood

“…To address the need for a clinically applicable intravital optical imaging system, we developed a new hardware and software framework. …”
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Normalized Transillumination of Fluorescent Proteins in Small Animals by Giannis Zacharakis, Helen Shih, Jorge Ripoll, Ralph Weissleder, Vasilis Ntziachristos

“…Although normalized transillumination does not match the accuracy and quantification capacity of tomographic imaging, it nevertheless attains key advantages over other planar optical imaging methods while preserving implementation simplicity. …”
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Integrated Confocal and Scanning Probe Microscopy for Biomedical Research by B.J. Haupt, A.E. Pelling, M.A. Horton

“…More frequently, it is being used in combination with other optical imaging methods, such as confocal laser scanning microscopy (CLSM) and fluorescent imaging, to provide a more comprehensive understanding of biological systems. …”
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Computer simulation of diffractive imaging lenses using hyperspectral images by S.I. Kharitonov, V.A. Fursov

“…We offer a computer technology for modeling a process of optical imaging with a diffractive imaging lens. The central idea of the technology is to evaluate the quality of the optical system by matching the input and output images against criteria adopted in image processing. …”
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Multifunctional Synthetic Poly(-Glutamic Acid)–Based Cancer Therapeutic and Imaging Agents by Marites P. Melancon, Chun Li

“…This review summarizes and updates our recent research on the use of PG as a platform for drug delivery and molecular imaging, including recent clinical findings with respect to PG-paclitaxel (PG-TXL), the combination of PG-TXL with radiotherapy, mechanisms of action of PG-TXL, and noninvasive visualization of in vivo delivery of polymeric conjugates with contrast-enhanced magnetic resonance imaging, optical imaging, and multimodality imaging.…”
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Viral Transgene Expression Delivered by Repeat Intraocular Adenoviral Vector Injection: in Vivo Live Imaging Study by Peter L. Gehlbach, Roy S. Chuck, Chung-Gyu Park, Choul Yong Park

“…Using this information, we were able to determine the optimal time point for readministration of Ad into the eyes and to dynamically study the time course of expression of a second Ad administration. Optical imaging demonstrated the limited period of transgene expression in eyes. …”
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Breast Cancer Imaging Using the Near-Infrared Fluorescent Agent, CLR1502 by Melissa L. Korb, Jason M. Warram, Joseph Grudzinski, Jamey Weichert, Justin Jeffery, Eben L. Rosenthal

“…Human breast cancer tumors can be imaged in vivo with multiple optical imaging platforms using CLR1502. This pilot study supports further investigations of this fluorescent agent for improving surgical resection of malignancies, with the goal of eventual clinical translation.…”
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Toxicity of Organic Fluorophores Used in Molecular Imaging: Literature Review by Raphael Alford, Haley M. Simpson, Josh Duberman, G. Craig Hill, Mikako Ogawa, Celeste Regino, Hisataka Kobayashi, Peter L. Choyke

“…Using relatively inexpensive and portable equipment, optical imaging with fluorophores permits real-time detection of cancer. …”
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Measuring Response to Therapy by Near-Infrared Imaging of Tumors Using a Phosphatidylserine-Targeting Antibody Fragment by Jian Gong, Richard Archer, Michael Brown, Seth Fisher, Connie Chang, Matthew Peacock, Christopher Hughes, Bruce Freimark

“…Tumor uptake of PGN650 was measured by near-infrared optical imaging in human tumor xenografts in immunodeficient mice. …”
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Super-resolution microscopy: Shedding new light on blood cell imaging by Huan Deng, Yan Ma, Yu-Hui Zhang

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Ultrasound-guided photoacoustic image annotation toolkit in MATLAB (PHANTOM) for preclinical applications by Allison Sweeney, Aayush Arora, Skye A. Edwards, Srivalleesha Mallidi

“…The PHANTOM toolkit provides scripts and auxiliary functions to enable biomedical researchers not specialized in optical imaging to apply fluence correction to PA images, enhancing accessibility of quantitative PAI for researchers in various fields.…”
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Molecular–Genetic Imaging: A Nuclear Medicine–Based Perspective by Ronald G. Blasberg, Juri Gelovani Tjuvajev

“…Noninvasive in vivo molecular–genetic imaging developed more recently and is based on nuclear (positron emission tomography [PET], gamma camera, autoradiography) imaging as well as magnetic resonance (MR) and in vivo optical imaging. Molecular–genetic imaging has its roots in both molecular biology and cell biology, as well as in new imaging technologies. …”
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