Analysis of central retinal microcirculation in glaucoma after neuroretinoprotective treatment by N.G. Glazko, A.E. Egorov

“…Conventional treatment for glaucomatous optic neuropathy (antioxidants, vasodilators, nootropic drugs, and retinoprotectors) was performed in the control group.…”
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Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report by Hemlata Bhaskar, Rekha Chaudhary

“…Deficiency of vitamin B12 clinically manifests as excessive daytime fatigue, memory difficulties, encephalopathy, myelopathy, peripheral neuropathy, and optic neuropathy. In occupational medicine, vitamin B12 deficiency has been reported with exposure to nitrous oxide in health care workers. …”
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A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model. by Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene

“…Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells (RGC). …”
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Pharmacotherapy, adverse drug reactions, and factors associated with clinical outcome in primary open-angle glaucoma by Anushree Dayanand, Sushma Muraraiah, S. Karthik Raja, Nishat Sultana Khayoom

“…Background: Glaucoma is a chronic, progressive optic neuropathy caused by a group of ocular conditions which lead to damage of the optic nerve with progressive diminution of vision. …”
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EFFICACY OF PHACOEMULSIFICATION AND PHACOEMULSIFICATION COMBINED WITH GONIOSYNECHIALYSIS IN SURGICAL TREATMENT OF CHRONIC ANGLE-CLOSURE GLAUCOMA: 2-YEARS STUDY by Igor Novytskyy, Rostyslav Lopadchak

“…Phaco was indicated in cases with IOP above 22 mmHg, appositional anterior chamber angle closure, and optic neuropathy; Phaco with GSL was indicated in cases of synechial angle closure and IOP above 22 mmHg Results. …”
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Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: A Prospective Study by Benjamin Wolff, Georges Azar, Vivien Vasseur, José-Alain Sahel, Catherine Vignal, Martine Mauget-Faÿsse

“…Those findings were found in 75% of eyes presenting hereditary OA, 50% of eyes presenting ischemic optic neuritis, 50% of eyes with drusen of the optic nerve (ON), 44.4% of eyes presenting a compressive OA, 32% of eyes presenting inflammatory optic neuropathy from multiple sclerosis, 18.5% of eyes presenting OA from undetermined origin, and 17.6% of eyes having primary open-angle glaucoma. …”
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Novel pathogenically oriented surgical technique for advanced glaucoma by A.Yu. Kazantzeva

“…Adequate intraocular pressure (IOP) lowering slows the progression of glaucomatous optic neuropathy and preserves vision. IOP-lowering agents and laser treatment for glaucoma are widely adopted, however, they provide short-term IOP-lowering effect. …”
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Graves’ Ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and Management by Jesús Barrio-Barrio, Alfonso L. Sabater, Elvira Bonet-Farriol, Álvaro Velázquez-Villoria, Juan C. Galofré

“…Although the majority of GO patients have a mild, self-limiting, and nonprogressive ocular involvement, about 3–7% of GO patients exhibit a severe sight-threatening form of the disease due to corneal exposure or compressive optic neuropathy. An appropriate assessment of both severity and activity of the disease warrants an adequate treatment. …”
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Clinical manifestations and outcomes of patients with intravascular large B-cell lymphoma with neurological involvement: highlighting longitudinally extensive myelopathy as a disti... by Jiraporn Jitprapaikulsan, Ekdanai Uawithya, Palakorn Lertsakworakul, Weerapat Owatthanapanich

“…Categorical variables were compared using the χ² or Fisher’s exact test, while continuous variables were analysed with the Mann-Whitney U test, as appropriate.Results Of the 30 patients with IVLBCL, 10 had neurological involvement and 20 without neurological symptoms, including myelopathy (5 patients, 50%); cognitive impairment (3 patients, 30%); seizures (2 patients, 20%); optic neuropathy, hemiparesis, homonymous hemianopia, vertigo and global aphasia (each affecting 1 patient, 10%). 60% of IVLBCL with neurological involvement had systemic symptoms, including prolonged fever, anaemia, anorexia and weight loss. …”
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Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study by Junqing Wang, Huanfen Zhou, Limin Qin, Chunxia Peng, Jie Zhao, Da Teng, Dahe Lin, Nanping Ai, Quangang Xu, Shihui Wei

“…At last follow-up, 14.5% were diagnosed with neuromyelitis optica spectrum disorder (NMOSD), 1.3% were diagnosed with multiple sclerosis (MS), 5.2% with chronic relapsing inflammatory optic neuropathy, 1.3% with infectious ON, and 19.7% with autoimmune ON. …”
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Peripapillary Microvascularization Analysis Using Swept-Source Optical Coherence Tomography Angiography in Optic Chiasmal Compression by Inès Ben Ghezala, Déa Haddad, Julie Blanc, Cyril Meillon, Rachid Madkouri, François Borsotti, Alain M. Bron, Catherine Creuzot-Garcher

“…Based on this neuro-ophthalmological examination, the presence of an optic neuropathy (ON) was evaluated. Peripapillary VD was obtained in four sectors on a 6 × 6 mm SS-OCTA image using the Cirrus Plex Elite 9000. …”
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Long-Term Followup Comparing Two Treatment Dosing Strategies of 125I Plaque Radiotherapy in the Management of Small/Medium Posterior Uveal Melanoma by Timothy G. Murray, Arnold M. Markoe, Aaron S. Gold, Fiona Ehlies, Ernesto Bermudez, Andrea Wildner, Azeema Latiff

“…Comparative analysis of the incidence rates of specific complications between the two groups demonstrates that group 2 had a significantly higher incidence of radiation retinopathy, radiation optic neuropathy, and/or visually significant cataract formation than group 1 (). …”
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Ophthalmic risk factors for primary open angle glaucoma by V.P. Erichev, A.V. Kuroyedov, S.Yu. Petrov, A.Yu. Brezhnev, A.A. Antonov, A.A. Vitkov, Yu.K. Murakhovskaya

“…<p> <i>Primary open angle glaucoma (POAG) is a chronic progressive optic neuropathy, characterized by morphological changes in the optic nerve head and retinal nerve fiber layer. …”
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Efficacy and safety of proton radiotherapy in treating choroidal melanoma: a systematic review and meta-analysis by Yuxin Miao, Tingwei Zheng, Qiuning Zhang, Meixuan Li, Qihang Lei, Qin Liu, Hongtao Luo, Huiling Bai

“…The most common adverse reactions after PBT were glaucoma, optic neuropathy, and cataracts, with incidence rates ranging from 17.9 to 27%, 12.8–64%, and 29.6–39.8%, respectively. …”
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Influence of Methylprednisolone Pulse Therapy on Liver Function in Patients with Graves’ Orbitopathy by Piotr Miśkiewicz, Anna Jankowska, Kinga Brodzińska, Justyna Milczarek-Banach, Urszula Ambroziak

“…Intravenous methylprednisolone (IVMP) pulse therapy is the first-line treatment in active moderate-to-severe Graves’ orbitopathy (GO) and dysthyroid optic neuropathy (DON). One of the adverse effects of this therapy is liver dysfunction that can be mild (ALT < 100 U/L), moderate (ALT: 100–300 U/L), and severe defined as acute liver injury (ALI) (ALT > 300 U/L). …”
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Evaluation of the structures of the optic nerve and chiasm in patients with skull base tumors using high-resolution MRI by Ekaterina S. Egorova, Valeriia V. Musulevska, Mykola O. Guk, Oksana Y. Skobska

“… Objective: To investigate the effectiveness of radiological methods for diagnosing optic nerve and chiasm atrophy in compressive optic neuropathy caused by tumors of the chiasmal-sellar region (CSR). …”
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Data mining and safety analysis of voriconazole in patients with a hematological malignant tumor based on the FAERS database: differences between children and adults by Hao Li, Hao Li, Manxue Jiang, Manxue Jiang, Xiaona Pan, Lingti Kong, Lingti Kong, Lingti Kong

“…The highest ROR signal intensities were found for “hallucinations, mixed” in children and “toxic optic neuropathy” in adults. The median time of onset of the ADE in children and adults was 11 and 8.5 days, respectively.ConclusionWe used four algorithms (ROR, PRR, BCPNN, MGPS) to mine the signals of voriconazole in patients with a hematological malignant tumor, and compared the differences between children and adults. …”
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Ocular Findings in COVID-19 Patients: A Review of Direct Manifestations and Indirect Effects on the Eye by Federica Bertoli, Daniele Veritti, Carla Danese, Francesco Samassa, Valentina Sarao, Nicolò Rassu, Tommaso Gambato, Paolo Lanzetta

“…Intensive care unit patients, due to risk factors like invasive mechanical ventilation, prone position, and multiresistant bacterial exposure, may develop ocular complications like ocular surface disorders, secondary infections, and less frequently acute ischemic optic neuropathy and intraocular pressure elevation. Among the array of drugs that have shown positive results, the use of hydroxychloroquine and chloroquine has raised a concern due to their well-known retinal toxic effects. …”
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Retinoprotective therapy of glaucoma by A.S. Makarova

“…Makarova </p> <p> Krasnov Research Institute of Eye Diseases, Moscow, Russian Federation </p> <p> <b>Background</b>: a fluctuating blood pressure (BP) and particularly an overnight hypotension is the key adverse factor leading to the progression of glaucomatous optic neuropathy. </p> <p> <b>Aim</b>: to study the effectiveness of a neuroprotective drug (a complex of water-soluble polypeptide fractions) in patients with unstable primary open-angle glaucoma and normalized ophthalmotonus by monitoring the morphological and functional parameters of the retina and optic nerve. …”
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Derivation and Characterization of Isogenic <i>OPA1</i> Mutant and Control Human Pluripotent Stem Cell Lines by Katherine A. Pohl, Xiangmei Zhang, Johnny Jeonghyun Ji, Linsey Stiles, Alfredo A. Sadun, Xian-Jie Yang

“…Dominant optic atrophy (DOA) is the most commonly inherited optic neuropathy. The majority of DOA is caused by mutations in the <i>OPA1</i> gene, which encodes a dynamin-related GTPase located to the mitochondrion. …”
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