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41
Rethinking Communication in Interactions with a Child with Autism: Ela, Her Father, and the Jellyfish in the Pool
Published 2025-01-01“…Taking a relational ontology stance, we use the concept of languaging as a continuous coordination of actions alongside the notion of assemblages of semiotic repertoires configured within multimodal and multisensory ecologies to analyze the communication between a child, Ela and her father, Gus, during a social activity at the pool. …”
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42
Identifying the Prophetic Legal Ethos in the Death Penalty Provisions of the Indonesian Criminal Code
Published 2024-11-01“…The concepts of humanization, liberation, and transcendence serve as foundational elements of the philosophical framework of prophetic law, which coherently and sequentially aligns with the structures of ontology, epistemology, and axiology. These concepts are employed as benchmarks to identify the prophetic legal ethos embedded within the death penalty provisions of the Indonesian Criminal Code. …”
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43
Rethinking contending themes in indigenous and Christian religions in contemporary Africa
Published 2024-06-01“…In the vast majority of deficit-prone literature, such themes as symbolism, liturgy, sacrifice, saints, sinners, and ontology, among others, are far from balanced. The extant gap has further increased the befuddling perception of African traditional religion by indigenous Christians as belonging to the “Kingdom of Satan” that needs salvation through the instrumentality of Christianity. …”
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44
The problem of the knowledge of the thinking substance in the Meditations and in the Objections and Replies of Rene Descartes
Published 2025-02-01“…It is concluded that in the Meditations, Descartes confronts an insurmountable gap between the ontology of substance and its knowledge, which prompts him to further develop and clarify his theory in later writings. …”
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45
EpigenomeViewer: A Shiny Web Application for Visualizing Methylation Patterns Across Biological Samples
Published 2025-02-01“…Future developments include expanded support for multi-omics data and additional gene ontology features. …”
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46
The transcriptomic footprint of Mytella strigata: de novo transcriptome assembly of a major invasive species
Published 2025-02-01“…A number of databases were used for functional annotation, including UniProt, KEGG, Reactome, InterPro, and eggNOG. Gene Ontology and pathway analyses identified transcripts associated with key biological processes, including those associated with cell signalling, metabolism, stress responses, cancer pathways, and immune regulation. …”
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47
Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer’s disease
Published 2025-02-01“…Further, cell-type distributions were more predictive of end-time-point tau pathology than AD-risk-gene expression. Using gene ontology analysis, we found that the genes that are directly correlated to tau pathology are functionally distinct from those that constitutively embody the vulnerable cells. …”
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48
Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases
Published 2023-09-01“…Among intervention types that can be mimicked by MR, only trials of pharmaceutical interventions could be automatically matched to MR results due to insufficient annotation with Medical Subject Headings ontology. A manual survey of the literature highlighted the potential for triangulation across a number of exposure/outcome pairs if these challenges can be addressed.Conclusions We conclude that careful triangulation of MR with RCT evidence should involve consideration of similarity of phenotypes across study designs, intervention intensity and duration, study population demography and health status, comparator group, intervention goal and quality of evidence.…”
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49
Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization
Published 2025-01-01“…Results: This study identified 14 core components and 105 stroke-related targets for ZBP. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that these targets are involved mainly in oxidative stress processes, lipid metabolism, and the PI3K–Akt signaling pathway. …”
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50
The Motives behind the Skepticism of Conventional Medicine Advocates towards Traditional Persian Medicine: An Expert Opinion
Published 2024-12-01“…Some critiques are because of a knowledge gap between ontology and epistemology of complementary medical approaches and conventional medicine. …”
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51
Lesbianism: Deconstructing the Christian church and social hierarchies in South Africa
Published 2023-11-01“…By highlighting how colonial impressions resulted in a homophobic reception of the bible, I argue for a positive reimagining between churches and the LGBTQI community and provide evidence that the Christian church and social hierarchies impact lesbian identity negatively through the implementation of the Biblical text and patriarchal ontology. [1] The term lesbian will be used to describe lesbian individuals with or without partners and children. …”
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52
Effect of genomic regions harboring putative lethal haplotypes on reproductive performance in closed experimental selection lines of Nellore cattle
Published 2025-02-01“…Forty-five genomic regions harboring putative lethal haplotypes were identified, which overlap with 360 genes. Gene ontology analyses of these genes revealed biological processes associated with the development of sexual traits in males and females, key functions of the immune system, energy homeostasis, and embryonic development. …”
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53
Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression
Published 2025-02-01“…We used cleavage under targets and tagmentation (CUT&Tag), gene set enrichment analysis, and behavioral tests after GRID1 (glutamate receptor delta-1 subunit) knockdown. Gene ontology and pathway enrichment analysis via CUT&Tag suggested the following mechanism for the antidepressant action of T2943: T2943 inhibits HDAC5 activity to promote H3K14 acetylation. …”
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54
Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis
Published 2025-02-01“…Molecular differences were assessed using Gene Ontology and KEGG analysis. Hypoxia, ferroptosis, pyroptosis, and parthanatos indices were calculated, and transcription factors were predicted using SENIC. …”
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55
The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD
Published 2025-02-01“…Microplastic exposure induced inflammatory cytokine secretion only for IL-8 production in controls (epithelial/ moMφs co-culture) and asthmatic (monoculture) epithelial cells in contrast to PM2.5, which was a strong inflammatory inducer. Gene Ontology analysis revealed that microplastic exposure affected sterol and cholesterol biosynthesis, secondary alcohol metabolism, and acetyl-CoA metabolism in asthma, and cell motility, chemokine signaling, leukocyte migration, and chemotaxis in COPD. …”
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56
The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer
Published 2024-11-01“…NOTCH1 expression was significantly up-regulated in cold tumors but down-regulated in hot tumors. The Gene ontology (GO) enrichment analysis of NOTCH1 with the two categories placed stress on angiogenesis and protein dealkylation, respectively. …”
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57
WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway
Published 2025-02-01“…Pathway enrichment exploration was conducted utilizing gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Set Enrichment Analysis (GSEA), and Metascape tools. …”
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58
Deciphering the multifaceted mechanism of Shuang Huang Lian in treating upper respiratory tract infections: A metabolomics-based network pharmacology approach
Published 2025-02-01“…A protein-protein interaction (PPI) network was constructed, and gene ontology (GO), KEGG, and Reactome enrichment analyses were conducted to elucidate the biological functions relevant to URTIs. …”
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59
Identification and functional analysis of energy metabolism and pyroptosis-related genes in diabetic nephropathy
Published 2025-02-01“…Subsequent analyses included Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, Gene Set Enrichment Analysis (GSEA), and Protein-Protein Interaction (PPI) network analysis. …”
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60
New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease
Published 2025-02-01“…Additionally, the study explored the targets of action for TPHP and DPHP using network toxicity analysis, conducted protein interaction analysis, and explored the functional aspects of action through Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. …”
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