Showing 1 - 20 results of 430 for search '"oncogene"', query time: 0.08s Refine Results
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    Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors by Andrei L. Gartel

    Published 2014-01-01
    “…The oncogenic transcription factor FOXM1 is one of the key regulators of tumorigenesis. …”
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    Article
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    Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma by Abdul Basit Ahanger, Syed Wajid Aalam, Tariq Ahmad Masoodi, Asma Shah, Meraj Alam Khan, Ajaz A. Bhat, Assif Assad, Muzafar Ahmad Macha, Muzafar Rasool Bhat

    Published 2025-01-01
    “…Conclusion We present a novel approach for the non-invasive prediction of deregulation in oncogenic signaling pathways in glioblastoma (GBM) by integrating radiogenomic data with machine learning models. …”
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    The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer by Kimberly A. Placzkowski, Honey V. Reddi, Stefan K. G. Grebe, Norman L. Eberhardt, Bryan McIver

    Published 2008-01-01
    “…The PAX8/PPARγ fusion gene appears to be an oncogene. It is most often expressed in follicular carcinomas and exerts a dominant-negative effect on wild-type PPARγ, and stimulates transcription of PAX8-responsive promoters. …”
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    Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

    Published 2024-12-01
    “…Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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    The Leukemic Stem Cell Niche: Adaptation to “Hypoxia” versus Oncogene Addiction by Giulia Cheloni, Martina Poteti, Silvia Bono, Erico Masala, Nathalie M. Mazure, Elisabetta Rovida, Matteo Lulli, Persio Dello Sbarba

    Published 2017-01-01
    “…The loss of oncogene addiction in SCN-adapted LSC has a consequence of crucial practical relevance: the refractoriness to inhibitors of the biological activity of oncogenic protein due to the lack of their molecular target. …”
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    Viral mimicry evasion: a new role for oncogenic KRAS mutations by Raymond Chen, Aobo He, Daniel D. De Carvalho

    Published 2025-02-01
    “…In a recent study, Zhou and colleagues identify KRAS, a frequently mutated oncogene, as a negative regulator of dsRNA and viral mimicry in an ICI‐resistant colorectal cancer model. …”
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