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    Advances in nucleic acid-based cancer vaccines by Hung-Chun Liao, Shih-Jen Liu

    Published 2025-01-01
    “…Abstract Nucleic acid vaccines have emerged as crucial advancements in vaccine technology, particularly highlighted by the global response to the COVID-19 pandemic. …”
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    Article
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    Recent Advances in Chemical Modification of Peptide Nucleic Acids by Eriks Rozners

    Published 2012-01-01
    “…Journal of Nucleic Acids…”
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    Article
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    Assessment for Melting Temperature Measurement of Nucleic Acid by HRM by Jing Wang, Xiaoming Pan, Xingguo Liang

    Published 2016-01-01
    “…High resolution melting (HRM), with a high sensitivity to distinguish the nucleic acid species with small variations, has been widely applied in the mutation scanning, methylation analysis, and genotyping. …”
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    Article
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    Nucleic Acid-Based Therapy Approaches for Huntington's Disease by Tatyana Vagner, Deborah Young, Alexandre Mouravlev

    Published 2012-01-01
    “…The aim of this paper is to outline the nucleic acid-based therapeutic strategies that have been tested to date.…”
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    Article
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    Cationic Cyclodextrin-Based Carriers for Drug and Nucleic Acid Delivery by Adila Nazli, Milo Malanga, Tamás Sohajda, Szabolcs Béni

    Published 2025-01-01
    “…The delivery systems for nucleic acids were also summarized while focusing on their condensation ability, transfection efficiency, and biocompatibility in comparison to commercially available vectors such as PEI 25 kDa and lipofectamine 2000. …”
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    Article
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    Dry Swab-Based Nucleic Acid Extraction vs. Spin Column-Based Nucleic Acid Extraction for COVID-19 RT-PCR Testing: A Comparative Study by Mohammed Faraaz Khan, C. Roopa

    Published 2023-01-01
    “…Conventional nucleic acid extraction involves usage of spin columns to isolate the RNA, but this is labor intensive. …”
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    Article
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    Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders by Md Jobair Jony, Ameya Joshi, Alekha Dash, Surabhi Shukla

    Published 2025-01-01
    “…Recent advancements in gene therapy, especially non-viral nucleic acid delivery systems like liposomes, solid lipid nanoparticles, dendrimers, and polymersomes, offer promising solutions. …”
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    Article
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    Rapid Diagnosis of Bacterial Infections Using Technologies Based on Nucleic Acid Detection by François J Picard, Michel G Bergeron

    Published 1999-01-01
    “…Novel diagnostic tests based on the detection of nucleic acids (DNA or RNA) offer a great potential for the rapid (approximately 1 h) diagnosis of bacterial infections. …”
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    Article
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    Assessment of Damage to Nucleic Acids and Repair Machinery in Salmonella typhimurium Exposed to Chlorine by M. H. Phe, M. Hajj Chehade, H. Guilloteau, C. Merlin, J. C. Block

    Published 2009-01-01
    “…In this paper, we hypothesized that a successful disinfection is achieved only when the applied chlorine leads to both intracellular nucleic acid damage and strong alterations of the DNA repair machinery. …”
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    Digital Melting Curve Analysis for Multiplex Quantification of Nucleic Acids on Droplet Digital PCR by Xiaoqing Dai, Meng Cao, Zunliang Wang

    Published 2025-01-01
    “…We present a cost-effective and simple multiplex nucleic acid quantification method using droplet digital PCR (ddPCR) with digital melting curve analysis (MCA). …”
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    Article
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    Application and Evaluation of [Tc]-Labeled Peptide Nucleic Acid Targeting in Breast Cancer Imaging by Yaqun Jiang MD, Yongkang Gai PhD, Yu Long MD, Qingyao Liu PhD, Chunbao Liu MD, PhD, Yongxue Zhang MD, Xiaoli Lan MD, PhD

    Published 2020-06-01
    “…It has been reported that dysregulation of microRNA-155 expression and function is associated with tumorigenesis, growth, tumor subtypes, invasion, and poor survival rates. Peptide nucleic acid (PNA), an artificially synthesized nucleic acid mimic, has been applied for molecular diagnosis. …”
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    NAPTUNE: nucleic acids and protein biomarkers testing via ultra-sensitive nucleases escalation by Tao Hu, Xinxin Ke, Yingying Yu, Hongmei Feng, Senfeng Zhang, Yinuo Cui, Boyang Zhang, Min He, Yinbing Tang, Lei Liu, Yu Lin, Quanquan Ji, Chuanxia Chen, Chunlong Xu, Chunyi Hu

    Published 2025-02-01
    “…Abstract In an era where swift and precise diagnostic capabilities are paramount, we introduce NAPTUNE (Nucleic acids and Protein Biomarkers Testing via Ultra-sensitive Nucleases Escalation), an innovative platform for the amplification-free detection of nucleic acids and protein biomarkers in less than 45 minutes. …”
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    Article