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321
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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322
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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323
Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice
Published 2025-01-01“…HAP-NPs, CDDP, and HAP-NPs + CDDP resulted in significant (P < 0.05) nucleic acid destruction, and significant (P < 0.05) overexpression of apoptotic-related genes (P53, Bax, and Bcl2) and proteins (Ki-67 and P53), causing the tumor bulk to be greatly reduced in HAP-NPs, CDDP, and HAP-NPs + CDDP (1100, 570, and 450 mm3), respectively, compared to ESC group was 2240 mm3. …”
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324
Glycine rich proteins of ticks: more than a cement component
Published 2024-08-01“…GRPs have been identified in a diverse array of organisms and have been shown to possess a number of distinctive biological characteristics, including nucleic acid binding, adhesive glue-like properties, antimicrobial activity, involvement in the stress response and in the formation of cuticle components. …”
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325
A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression
Published 2025-01-01“…In this study, matrix metalloproteinase-13 siRNA (siMMP-13) was incorporated onto polyethylenimine (PEI)-polyethylene glycol (PEG) modified Fe3O4 nanoparticles, forming a nucleic acid nanocarrier termed si-Fe NPs. Subsequently, a poly(vinyl alcohol) (PVA) crosslinked phenylboronic acid (PBA)-modified hyaluronic acid (HA) hydrogel (HPP) was used to encapsulate the si-Fe NPs, resulting in a bifunctional hydrogel (si-Fe-HPP) with reactive oxygen species (ROS)-responsive and RNAi therapeutic properties. …”
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326
Efficiency enhancement in main path extraction in mRNA vaccine field: A novel approach leveraging intermediate patents, with shielding origin and terminus patent edges
Published 2025-12-01“…The patents on the main paths predominantly focus on nucleic acid modifications and delivery systems. The local backward main paths identify a greater number of patents, especially those related to litigation, offering a richer and more diverse set of technological insights. …”
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327
Bacteriophage Treatment Induces Phenotype Switching and Alters Antibiotic Resistance of ESBL <i>Escherichia coli</i>
Published 2025-01-01“…The downregulated proteins were involved in various metabolic pathways, including nucleic acid, protein and lipid metabolism, and iron acquisition. …”
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328
Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics
Published 2018-01-01“…Targeted needle biopsies are increasingly performed for the genetic characterization of cancer. While the nucleic acid content of core needle biopsies after standard pathology processing (i.e., formalin fixation and paraffin embedding (FFPE)) has been previously reported, little is known about the potential yield for molecular analysis at the time of biopsy sample acquisition. …”
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329
Biological Characteristics and Whole-Genome Analysis of a Porcine <i>E. coli</i> Phage
Published 2025-01-01“…Psq-1 exhibited a significant inhibitory effect on <i>E. coli</i> in liquid culture medium. The nucleic acid type of phage Psq-1 was dsDNA, with a total genome length of 44,183 bp and a GC content of 52.16%. …”
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330
Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection
Published 2020-01-01“…Although the prognosis is good, isolation is critical for asymptomatic patients, and it is important not to end isolation early before a nucleic acid test turns negative.…”
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331
Two-dimensional semantic morphological feature extraction and atlas construction of maize ear leaves
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332
The protein structurome of Orthornavirae and its dark matter
Published 2025-02-01“…Nevertheless, a variety of lineage-specific globular domains that were new either to orthornaviruses in general or to particular virus families were identified within the proteomic dark matter of orthornaviruses, including several predicted nucleic acid-binding domains and nucleases. In addition, we identified a case of exaptation of a cellular nucleoside monophosphate kinase as an RNA-binding protein in several virus families. …”
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333
A Spike-Based mRNA Vaccine Encapsulated in Phospholipid 1,2-Dioleoyl-sn-Glycero-3-PhosphoEthanolamine Containing Lipid Nanoparticles Induced Potent B- and T-Cell Responses Associat...
Published 2025-01-01“…Studies on using the mRNA/LNP platform for vaccines have largely focused on the nucleic acid cargo with less attention paid to the LNP vehicle. …”
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334
Rap1 and mTOR signaling pathways drive opposing immunotoxic effects of structurally similar aryl-OPFRs, TPHP and TOCP
Published 2025-01-01“…These results revealed comparable disturbances induced by both compounds, including disruptions in nucleic acid synthesis and energy metabolism, blocking ADP to ATP conversion by reducing TCA cycle intermediates, consequently leading to ATP depletion. …”
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335
Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting Neisseria gonorrhoeae in urine specimens
Published 2025-01-01“…ABSTRACT Nucleic acid amplification testing (NAAT) for N. gonorrhoeae is unavailable in resource-limited settings. …”
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336
First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan
Published 2025-04-01“…Children under 5 years of age exhibited a higher nucleic acid detection rate compared to older age groups, suggesting the importance of molecular testing in younger patients particularly in the early detection of Parvovirus B19 during the acute phase of infection, before the body has developed detectable antibodies and also in immunocompromised children, who may not mount an antibody response detectable by serological methods. …”
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337
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338
African army ants at the forefront of virome surveillance in a remote tropical forest
Published 2023-03-01“…Using 209 army ant samples collected from 29 colonies and the virion-associated nucleic acid-based metagenomics approach, we showed that a broad diversity of bacterial, plant, invertebrate and vertebrate viral sequences were accumulated by army ants: including sequences from 157 different viral genera in 56 viral families. …”
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339
Jet Injection of Naked mRNA Encoding the RBD of the SARS-CoV-2 Spike Protein Induces a High Level of a Specific Immune Response in Mice
Published 2025-01-01“…The development of naked mRNA vaccines could improve vaccine tolerability. Naked nucleic acid delivery using the jet injection method may be a solution. …”
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340
Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles
Published 2024-12-01“…The development of effective preparations capable of acting on target nucleic acids in cells is an urgent task. The aim of the study is to create nanocomplexes consisting of aminopropylsilanol nanoparticles and short interfering RNA (siRNA) to study their effect on target nucleic acids by the example of inhibition of influenza A virus replication in vitro. …”
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