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241
Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae
Published 2022-12-01“…Actinomycetes' inhibitory mechanism ranges from inhibition of cell wall synthesis to nucleic acid and protein synthesis. One Way ANOVA test showed significant differences between the inhibition zone produced by each fermentation group. …”
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242
De novo design of protein minibinder agonists of TLR3
Published 2025-01-01“…Abstract Toll-like Receptor 3 (TLR3) is a pattern recognition receptor that initiates antiviral immune responses upon binding double-stranded RNA (dsRNA). Several nucleic acid-based TLR3 agonists have been explored clinically as vaccine adjuvants in cancer and infectious disease, but present substantial manufacturing and formulation challenges. …”
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243
Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis
Published 2022-07-01“…The biological processes of genes expressed at higher levels in PTC LNM compared to PTC LNN were involved in cell communication, energy pathway, and metabolism, whereas ion transport, energy pathways, and regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolisms, were downregulated. Conclusion: These findings provide further evidence for the role of cellular transport regulatory processes in metastatic disease. …”
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244
Localisation of Abundant and Organ-Specific Genes Expressed in Rosa hybrida Leaves and Flower Buds by Direct In Situ RT-PCR
Published 2012-01-01“…In situ PCR is a technique that allows specific nucleic acid sequences to be detected in individual cells and tissues. …”
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245
DNA MITOKONDRIA (mtDNA) SEBAGAI SALAH SATU PEMERIKSAAN ALTERNATIF UNTUK IDENTIFIKASI BAYI PADA KASUS INFANTISIDA
Published 2017-07-01“…Penggunaan DNA (Deoxyribose Nucleic Acid) mitokondria atau mtDNA sebagai salah satu cara untuk mengetahui hubungan antara barang bukti medis dengan pelaku berkembang pesat setelah era 90an. …”
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246
An anatomical aspect on masseteric muscles in cattle rabies by real-time pcr
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247
Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification
Published 2025-01-01“…However, the complexity of the PCR process (including nucleic acid extraction/purification, amplification, and amplicon detection) hinders its widespread adoption in point-of-care testing, where simplicity and rapidity are essential for practical use. …”
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248
Supramolecular Biopolymers for Tissue Engineering
Published 2021-01-01“…In this review, we will analyse the 3 subtypes of SBPs: peptide-, nucleic acid-, and oligosaccharide-derived. Then, we will discuss the role that SBPs will be playing in TE as dynamic scaffolds, therapeutic scaffolds, and bioinks. …”
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249
Research on the Cross-Regional Traveling Welcome Short Messaging Service During the COVID-19 Pandemic: A Survey from Mobile Users’ Perspective
Published 2025-01-01“…Reminders about traveling registration and nucleic acid testing were assigned the highest importance, as they offer convenience in communicating the most up-to-date prevention and control information to mobile users during intercity travel. …”
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250
Transcytosis of T4 Bacteriophage Through Intestinal Cells Enhances Its Immune Activation
Published 2025-01-01“…Interactions between bacteriophages with mammalian immune cells are of great interest and most phages possess at least one molecular pattern (nucleic acid, sugar residue, or protein structure) that is recognizable to the immune system through pathogen associated molecular pattern (PAMP) receptors (i.e., TLRs). …”
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251
A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the “Dynamic Zero” Period
Published 2023-01-01“…The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. …”
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252
Gene Editing in Pluripotent Stem Cells and Their Derived Organoids
Published 2021-01-01“…Gene-editing technologies, from large-scale nucleic acid endonucleases to CRISPR, have ignited a global research and development boom with significant implications in regenerative medicine. …”
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253
Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates
Published 2021-01-01“…Cell viability and low nucleic acid expression are the problems related to dendritic cells (DCs) and mesenchymal stem cells (MSCs), which are transfected with plasmid DNA. …”
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254
Role of ixodid ticks in tick-borne pathogen spread and circulation in the Belarusian Lakeland
Published 2024-03-01“….), Babesia spp. and Tick-borne encephalitis virus genetic materials with real-time polymerase chain reaction using the reagent kit for nucleic acid extraction from environmental samples in accordance with the manufacturer’s instructions. …”
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255
Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China
Published 2025-02-01“…Direct identification of infected tissues is currently the primary method of diagnosis; however, the low sensitivity and inconvenience of microscopic examination in detecting amastigotes, parasitic manifestations of Leishmania, leads to the possibility of misdiagnosis, delayed diagnosis, and underdiagnosis.MethodsWith the development of metagenomic nextgeneration sequencing (mNGS) technology for pathogen identification, it is possible to detect specific nucleic acid sequences characteristic of Leishmania parasites, which opens new avenues for the more accurate diagnosis of leishmaniasis. …”
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256
Prion meeting 2023: implications of a growing field
Published 2024-12-01“…John Stanley Griffith hypothesized that the agent causing these diseases was “probably a protein without nucleic acid” and, in 1982, Stanley Prusiner reported the identification of a proteinaceous infectious particle (coining the term prion) that was resistant to inactivation methods that were at the time standard for nucleic acids, and identified PrP as the major protein component of the infectious agent in scrapie and in Creutzfeldt-Jakob disease, classifying this also as a prion disease. …”
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257
The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic
Published 2023-01-01“…Daily surveillance inspection in laboratories can remind laboratories to strictly comply with standard procedures, focus on laboratory quality control, and reduce the occurrence of false-positive cases in SARS-CoV-2 nucleic acid tests to some extent. This study recommends that government decision-making departments establish policies and arrange experts to conduct daily surveillance inspections to improve laboratory quality control.…”
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258
Bacterial Diversity Associated with Terrestrial and Aquatic Snails
Published 2024-12-01“…The steadfast technological progress in nucleic acid-based approaches would cause one to expect that scientific works on the microbial symbionts of animals would be balanced at least for the farmed animals of human interest. …”
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259
Analysis of the Effect of Female Genital Tuberculosis on Ovarian Reserve Parameters
Published 2023-04-01“…Materials and Methods: A total of 133 infertile women who underwent diagnostic hysterolaparoscopy and cartridge-based nucleic acid amplification test testing of an endometrial biopsy were included in the study. …”
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260
Mycoplasma pneumoniae detections in children with acute respiratory infection, 2010–2023: a large sample study in China
Published 2025-01-01“…Methods Children with ARTIs admitted to the Children’s Hospital of Soochow University (SCH) from January 2010 to December 2023 and underwent MP nucleic acid PCR assay were included. Clinical data on age, sex, onset time and detection result were collected and analyzed. …”
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