Suggested Topics within your search.
Showing 241 - 260 results of 425 for search '"nucleic acid"', query time: 0.06s Refine Results
  1. 241

    Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae by Annisa Nur Insani, Meiskha Bahar, Nunuk Nugrohowati, Retno Yulianti

    Published 2022-12-01
    “…Actinomycetes' inhibitory mechanism ranges from inhibition of cell wall synthesis to nucleic acid and protein synthesis. One Way ANOVA test showed significant differences between the inhibition zone produced by each fermentation group. …”
    Get full text
    Article
  2. 242

    De novo design of protein minibinder agonists of TLR3 by Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

    Published 2025-01-01
    “…Abstract Toll-like Receptor 3 (TLR3) is a pattern recognition receptor that initiates antiviral immune responses upon binding double-stranded RNA (dsRNA). Several nucleic acid-based TLR3 agonists have been explored clinically as vaccine adjuvants in cancer and infectious disease, but present substantial manufacturing and formulation challenges. …”
    Get full text
    Article
  3. 243

    Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis by Wan Fahmi Wan Mohamad Nazarie, Azliana Mohamad Yusof, Francis Yew Fu Tieng, Nur Fadhlina Mohamad Pakarulrazy, Rohaizak Muhammad, Shahrun Niza Abdullah Suhaimi, Nani Harlina Md Latar, Sazuita Saidin, Isa Mohamed Rose, Learn-Han Lee, Nurul-Syakima Ab Mutalib

    Published 2022-07-01
    “…The biological processes of genes expressed at higher levels in PTC LNM compared to PTC LNN were involved in cell communication, energy pathway, and metabolism, whereas ion transport, energy pathways, and regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolisms, were downregulated. Conclusion: These findings provide further evidence for the role of cellular transport regulatory processes in metastatic disease. …”
    Get full text
    Article
  4. 244

    Localisation of Abundant and Organ-Specific Genes Expressed in Rosa hybrida Leaves and Flower Buds by Direct In Situ RT-PCR by Agata Jedrzejuk, Heiko Mibus, Margrethe Serek

    Published 2012-01-01
    “…In situ PCR is a technique that allows specific nucleic acid sequences to be detected in individual cells and tissues. …”
    Get full text
    Article
  5. 245

    DNA MITOKONDRIA (mtDNA) SEBAGAI SALAH SATU PEMERIKSAAN ALTERNATIF UNTUK IDENTIFIKASI BAYI PADA KASUS INFANTISIDA by Taufik Hidayat

    Published 2017-07-01
    “…Penggunaan DNA (Deoxyribose Nucleic Acid) mitokondria atau mtDNA sebagai salah satu cara untuk mengetahui hubungan antara barang  bukti  medis  dengan  pelaku  berkembang  pesat  setelah  era  90an.  …”
    Get full text
    Article
  6. 246

    An anatomical aspect on masseteric muscles in cattle rabies by real-time pcr by Atilla Yoldaş, Ramazan İlgün, Nevin Tuzcu, Akın Yığın, Erdal Özmen

    “…<p> <b>Results:</b> The rabies virus specific nucleic acid was detected in masseter muscles motor nerves; N. mandibularis branch of N. trigeminus, N. masticatorius, motor leaf of N. mandibularis, N. massetericus and Nn. temporalis profunda which are two extra branches of N. masticatorius, unilaterally ganglion trigeminale, and pons by Real Time-PCR. …”
    Get full text
    Article
  7. 247

    Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification by Dohwan Lee, Tae Seok Seo

    Published 2025-01-01
    “…However, the complexity of the PCR process (including nucleic acid extraction/purification, amplification, and amplicon detection) hinders its widespread adoption in point-of-care testing, where simplicity and rapidity are essential for practical use. …”
    Get full text
    Article
  8. 248

    Supramolecular Biopolymers for Tissue Engineering by Rosario Pérez-Pedroza, Alan Ávila-Ramírez, Zainab Khan, Manola Moretti, Charlotte A. E. Hauser

    Published 2021-01-01
    “…In this review, we will analyse the 3 subtypes of SBPs: peptide-, nucleic acid-, and oligosaccharide-derived. Then, we will discuss the role that SBPs will be playing in TE as dynamic scaffolds, therapeutic scaffolds, and bioinks. …”
    Get full text
    Article
  9. 249

    Research on the Cross-Regional Traveling Welcome Short Messaging Service During the COVID-19 Pandemic: A Survey from Mobile Users’ Perspective by Zhiyuan Yu, Chi Zhang

    Published 2025-01-01
    “…Reminders about traveling registration and nucleic acid testing were assigned the highest importance, as they offer convenience in communicating the most up-to-date prevention and control information to mobile users during intercity travel. …”
    Get full text
    Article
  10. 250

    Transcytosis of T4 Bacteriophage Through Intestinal Cells Enhances Its Immune Activation by Amanda Carroll-Portillo, October Barnes, Cristina N. Coffman, Cody A. Braun, Sudha B. Singh, Henry C. Lin

    Published 2025-01-01
    “…Interactions between bacteriophages with mammalian immune cells are of great interest and most phages possess at least one molecular pattern (nucleic acid, sugar residue, or protein structure) that is recognizable to the immune system through pathogen associated molecular pattern (PAMP) receptors (i.e., TLRs). …”
    Get full text
    Article
  11. 251

    A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the “Dynamic Zero” Period by Xiaona Li, Ruili Li, Qiguo Lian, Yang Wang, Wenkui Gu, Qinghe Meng

    Published 2023-01-01
    “…The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. …”
    Get full text
    Article
  12. 252

    Gene Editing in Pluripotent Stem Cells and Their Derived Organoids by Hang Zhou, Yun Wang, Li-Ping Liu, Yu-Mei Li, Yun-Wen Zheng

    Published 2021-01-01
    “…Gene-editing technologies, from large-scale nucleic acid endonucleases to CRISPR, have ignited a global research and development boom with significant implications in regenerative medicine. …”
    Get full text
    Article
  13. 253

    Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates by Amin Hadi, Abbas Rastgoo, Maryam Eskandarian, Nooshin Haghighipour, Azam Bolhassani

    Published 2021-01-01
    “…Cell viability and low nucleic acid expression are the problems related to dendritic cells (DCs) and mesenchymal stem cells (MSCs), which are transfected with plasmid DNA. …”
    Get full text
    Article
  14. 254

    Role of ixodid ticks in tick-borne pathogen spread and circulation in the Belarusian Lakeland by A. A. Osmolovsky, I. A. Subotsina

    Published 2024-03-01
    “….), Babesia spp. and Tick-borne encephalitis virus genetic materials with real-time polymerase chain reaction using the reagent kit for nucleic acid extraction from environmental samples in accordance with the manufacturer’s instruc­tions. …”
    Get full text
    Article
  15. 255

    Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China by Rui Zhao, Guilun He, Lin Xiang, Melinda Ji, Rongheng He, Xudong Wei

    Published 2025-02-01
    “…Direct identification of infected tissues is currently the primary method of diagnosis; however, the low sensitivity and inconvenience of microscopic examination in detecting amastigotes, parasitic manifestations of Leishmania, leads to the possibility of misdiagnosis, delayed diagnosis, and underdiagnosis.MethodsWith the development of metagenomic nextgeneration sequencing (mNGS) technology for pathogen identification, it is possible to detect specific nucleic acid sequences characteristic of Leishmania parasites, which opens new avenues for the more accurate diagnosis of leishmaniasis. …”
    Get full text
    Article
  16. 256

    Prion meeting 2023: implications of a growing field by Tiago F. Outeiro, Tuane C. R. G. Vieira

    Published 2024-12-01
    “…John Stanley Griffith hypothesized that the agent causing these diseases was “probably a protein without nucleic acid” and, in 1982, Stanley Prusiner reported the identification of a proteinaceous infectious particle (coining the term prion) that was resistant to inactivation methods that were at the time standard for nucleic acids, and identified PrP as the major protein component of the infectious agent in scrapie and in Creutzfeldt-Jakob disease, classifying this also as a prion disease. …”
    Get full text
    Article
  17. 257

    The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic by Li-Li Liu, Yu-Hong Zheng, You-Quan Zhang, Jin-Piao Lin, Zhi-Lin Luo, Liu-Min Yu, Shi-Hua Gao, Falin Chen

    Published 2023-01-01
    “…Daily surveillance inspection in laboratories can remind laboratories to strictly comply with standard procedures, focus on laboratory quality control, and reduce the occurrence of false-positive cases in SARS-CoV-2 nucleic acid tests to some extent. This study recommends that government decision-making departments establish policies and arrange experts to conduct daily surveillance inspections to improve laboratory quality control.…”
    Get full text
    Article
  18. 258

    Bacterial Diversity Associated with Terrestrial and Aquatic Snails by Konstantinos Apostolou, Canella Radea, Alexandra Meziti, Konstantinos Ar. Kormas

    Published 2024-12-01
    “…The steadfast technological progress in nucleic acid-based approaches would cause one to expect that scientific works on the microbial symbionts of animals would be balanced at least for the farmed animals of human interest. …”
    Get full text
    Article
  19. 259

    Analysis of the Effect of Female Genital Tuberculosis on Ovarian Reserve Parameters by Sharma Richa, Kanhere Anjali, Jain Sonal, Jain Akrati

    Published 2023-04-01
    “…Materials and Methods: A total of 133 infertile women who underwent diagnostic hysterolaparoscopy and cartridge-based nucleic acid amplification test testing of an endometrial biopsy were included in the study. …”
    Get full text
    Article
  20. 260

    Mycoplasma pneumoniae detections in children with acute respiratory infection, 2010–2023: a large sample study in China by Yuzhu Miao, Jungen Li, Linlin Huang, Ting Shi, Tingbo Jiang

    Published 2025-01-01
    “…Methods Children with ARTIs admitted to the Children’s Hospital of Soochow University (SCH) from January 2010 to December 2023 and underwent MP nucleic acid PCR assay were included. Clinical data on age, sex, onset time and detection result were collected and analyzed. …”
    Get full text
    Article