Suvorexant, a Novel Dual Orexin Receptor Antagonist, for the Management of Insomnia by Andrew H. Han, Caroline R. Burroughs, Evan P. Falgoust, Jamal Hasoon, Grace Hunt, Juyeon Kakazu, Tim Lee, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…While there are existing treatments that target different receptors and pathways of normal sleep induction and maintenance, Suvorexant is a novel drug that targets dual orexin receptors. Its safety and efficacy, mechanism of action, pharmacokinetic parameters, and relative lack of rebound and withdrawal effects render suvorexant a reliable choice for the treatment of insomnia.…”
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Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility by Carmelo Scarpignato, Iva Pelosini

“…Among the motor- inhibiting drugs, gut selective muscarinic antagonists (such as zamifenacin and darifenacin), neurokinin2 antagonists (such as MEN-10627 and MEN-11420), beta3-adrenoreceptor agonists (eg, SR-58611A) and GI-selective calcium channel blockers (eg, pinaverium bromide and octylonium) are able to decrease painful contractile activity in the gut (antispasmodic effect), without significantly affecting other body functions. Novel mechanisms to stimulate GI motility and transit include blockade of cholecystokinin (CCK)A receptors and stimulation of motilin receptors. …”
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Investigation of the flow characteristics of slit check dams using novel models by Muhammet Emin Emiroglu, Erdinc Ikinciogullari, Eyyup Ensar Yalcin, Enes Gul

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A Novel Prescribed-Time Convergence Acceleration Algorithm with Time Rescaling by Xuehui Mei, Pengrui Zhang, Haijun Jiang, Zhiyong Yu

“…In order to ensure that the optimization problem converges to the optimal solution within the prescribed time, a novel prescribed-time convergence acceleration algorithm with time rescaling is presented in this paper. …”
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Novel insights into palatal shelf elevation dynamics in normal mouse embryos by Jeremy P. Goering, Michael Moedritzer, Marta Stetsiv, Dona Greta Isai, Brittany M. Hufft-Martinez, An J. Tran, Zaid Umar, Madison K. Rickabaugh, Paul Keselman, Munish Chauhan, Pamela V. Tran, William M. Brooks, William M. Brooks, Kenneth J. Fischer, Andras Czirok, Andras Czirok, Irfan Saadi, Irfan Saadi

“…Thus, our data reveal novel insights into rapid dynamic changes during PS elevation, and lay the foundation for future studies of normal and abnormal palatogenesis.…”
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Biocompatibility of variable thicknesses of a novel directly printed aligner in orthodontics by Maximilian Bleilöb, Claudia Welte-Jzyk, Vanessa Knode, Björn Ludwig, Christina Erbe

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Novel Algorithms for Solving a System of Absolute Value Variational Inequalities by Safeera Batool, Muhammad Aslam Noor, Riaz Ahmad, Ilyas Khan, Mulugeta Andualem

“…Absolute value variational inequalities present a rational, pragmatic, and novel framework for investigating a wide range of equilibrium problems that arise in a variety of disciplines. …”
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Novel Method for 5G Systems NLOS Channels Parameter Estimation by Vladeta Milenkovic, Stefan Panic, Dragan Denic, Dragan Radenkovic

“…For the development of new 5G systems to operate in mm bands, there is a need for accurate radio propagation modelling at these bands. In this paper novel approach for NLOS channels parameter estimation will be presented. …”
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A Novel Computer Virus Propagation Model under Security Classification by Qingyi Zhu, Chen Cen

“…Inspired by these facts, this paper presents a novel computer virus dynamics model considering the impact brought by security classification in full interconnection network. …”
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Analysis of the Fractional-Order Kaup–Kupershmidt Equation via Novel Transforms by Naveed Iqbal, Humaira Yasmin, Ali Rezaiguia, Jeevan Kafle, A. Othman Almatroud, Taher S. Hassan

“…This technique is a mixture of the novel integral transformation Elzaki transformation and the new iteration technique. …”
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Soy 11S Globulin Acid Subunits as the Novel Food Polymer Carrier by Lei Chen, Dahai Liu, Guohua Wu, Yuanyuan Ma

“…The results indicated that soy 11S globulin acid subunits were suitable novel carriers for aflatoxin antigen in immunization experiments and clone 4C5 could be used for simultaneous analysis of total aflatoxins.…”
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Endoscopic Measurement of Polyp Size Using a Novel Calibrated Hood by Keiichiro Kume, Tatsuyuki Watanabe, Ichiro Yoshikawa, Masaru Harada

“…We have therefore developed a novel calibrated hood that enables accurate measurement of polyp size during colonoscopy. …”
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A Novel BA Complex Network Model on Color Template Matching by Risheng Han, Shigen Shen, Guangxue Yue, Hui Ding

“…A novel BA complex network model of color space is proposed based on two fundamental rules of BA scale-free network model: growth and preferential attachment. …”
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Brucella-Induced Acute Psychosis: A Novel Cause of Acute Psychosis by Chi-Chi Obuaya, Gayathri Thivyaa Gangatharan, Efthimia Karra

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Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics by Jiangxue Qu, Hai Jiang, Huifeng Shi, Nana Huang, Jiawen Su, Yan Zhang, Lian Chen, Yangyu Zhao

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A Novel Optimization Method for Nonconvex Quadratically Constrained Quadratic Programs by Hongwei Jiao, Yong-Qiang Chen, Wei-Xin Cheng

“…This paper presents a novel optimization method for effectively solving nonconvex quadratically constrained quadratic programs (NQCQP) problem. …”
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A Novel Metamaterial MIMO Antenna with High Isolation for WLAN Applications by Nguyen Khac Kiem, Huynh Nguyen Bao Phuong, Quang Ngoc Hieu, Dao Ngoc Chien

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A Novel Study of Graphs Based on m-Polar Cubic Structures by G. Muhiuddin, A. M. Alanazi, A. Mahboob, A. H. Alkhaldi, Wejdan Alatwai

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A Novel Mutation in the Adult-Onset Alexander’s Disease GFAP Gene by Dhillon B. Zaver, Nathan T. Douthit

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Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation by Xu-Dong Lian, Yong Guan, Yue Jiang, Dong-Heui Kwak, Mi-Kyung Lee, Zhun Li

“…However, their utilization is frequently constrained by challenges such as high molecular weights and indistinct sugar chain structures. Recently, two novel bacterial strains, N6T and J3T, were isolated from the Nakdong River in Korea. …”
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