The Long-Term Outcome Comparison of Different Time-Delayed Kallikrein Treatments in a Mouse Cerebral Ischemic Model by Yaohui Ni, Kefu Cai, Yujie Hu, Chuan-hui Wang, Yuanyuan Zhang, Hua Huang, Xing Su, Jin-hua Gu

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Effect of frailty on the short-term functional outcome of elderly patients with traumatic brain injury by Yujing Gu, Huiqin Cui, Yang Gu, Xiaojiang Liu

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Development of a Novel Sensor System Based on Magnetic Microspheres to Detect Cardiac Troponin T by Junrong Zhang, Hongxiang Liu, Baofeng Xu, Sijun Huang, Rui Liu, Jinming Zhu, Yi Guo, Li Xu

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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

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The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells by Po-An Tai MD, PhD, Yen-Lin Liu MD, PhD, Ya-Ting Wen MD, Chien-Min Lin MD, PhD, Thanh-Tuan Huynh MD, PhD, Michael Hsiao DVM, PhD, Alexander T. H. Wu PhD, Li Wei MD, PhD

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From registration, protocol to report: are COVID-19-related RCTs in mainland China consistent? A systematic review of clinical trial registry and literature by Yu Chen, Ruiqing Yan

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Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study by Songfeng Zhao, Yangbin Cao, Hongyi Liu, Aihua Liu

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History of Pain Research and Management in Canada by Harold Merskey

“…Partly because of this early start with prominent figures and partly because of its social system in the organization of medicine, Canada became a centre for a number of aspects of pain research and management, ranging from pain clinics in Halifax, Kingston and Saskatoon - which were among the earliest to advance treatment of pain - to studying the effects of implanted electrodes for neurosurgery. Work in Toronto by Moldofsky and Smythe was probably responsible for turning ideas about fibromyalgia from the quaint concept of 'psychogenic rheumatism' into the more fruitful avenue of empirical exploration of brain function, muscle tender points and clinical definition of disease. …”
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Correlation Between the Grade of Hydronephrosis with Surgical Outcomes After Ultrasound-guided Supine Percutaneous Nephrolithotomy: A Retrospective Observational Study by Tiopan NAPITUPULU, Yosua HARDJA, Martin SUSANTO, Grace Dumamawarni HUTAHAEAN, Ika RIANTRI, Hendra SUTAPA, Yusuf RACHMAN, Andre Marolop Pangihutan SIAHAAN

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Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel by Seungkyu Choi, Jai Hyang Go, Eun Kyung Kim, Hojung Lee, Won Mi Lee, Chun-Sung Cho, Kyudong Han

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Gastrostomy uptake in motor neurone disease: a mixed-methods study of patients’ decision making by Natalie James, Emma Power, Anne Hogden, Julie Labra, Victoria M Flood

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Cuproptosis Cell Death Molecular Events and Pathways to Liver Disease by Mao Y, Chen H, Zhu W, Ni S, Luo S, Tang S, Chen Z, Wang Q, Xu J, Tu Q, Chen H, Zhu L

“…Yun Mao,1,* Huilan Chen,1,* Weihan Zhu,2 Shunlan Ni,3 Shengnan Luo,3 Shiyue Tang,3 Zhiyi Chen,4 Qin Wang,3 Jinxian Xu,3 Qi Tu,5 Haijun Chen,3,* Lujian Zhu3,* 1Department of Gerontology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China; 2The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 3Department of Infectious Disease, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China; 4Department of Gastroenterology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China; 5Department of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lujian Zhu; Haijun Chen, Department of Infectious Disease, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, People’s Republic of China, Email zhulj_brave@163.com; 19564367335@163.comAbstract: Chronic liver disease ranks as the 11th leading cause of death worldwide, while hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality, representing a substantial risk to public health. …”
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Predicting the risk of hematoma expansion in acute intracerebral hemorrhage: the GIVE score by Tian-Nan Yang, Xin-Ni Lv, Zi-Jie Wang, Xiao Hu, Li-Bo Zhao, Jing Cheng, Qi Li

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Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation by Shuxiao Chen, Xiaotian Liu, Xincheng Zhou, Weixiao Lin, Minting Liu, Haoran Ma, Keli Zhong, Qiming Ma, Chengjian Qin, Chengjian Qin

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Respiratory dysfunction in whiplash associated disorders (WAD) with cervical plexus syndrome – A case report by NA Nystrom, SR Daulat, A Zakaria, M Petersen, VM Moodley, LP. Champagne

“…In 2019, his condition deteriorated, with significantly increased pain and dyspnea leading to further evaluations that included laboratory studies and consultations with specialists in neurosurgery, neurology, pulmonology, neurophysiology, ENT, general internal medicine, cardiology, radiology, speech pathology, physical medicine, orthopedic surgery, and hand surgery at three separate academic centers in Norway.Eventually, the patient was diagnosed with a condition that is regularly observed among patients referred to our office for evaluation and surgical treatment of chronic, whiplash related pain, and that we propose to label Cervical Plexus Syndrome.One year following exploration and neurolysis of sensory nerves to the right and left superficial cervical plexus, the patient remains pain free, with unimpeded speech and breathing as demonstrated by postoperative spirometry and video recordings.Although the underlying pathophysiology remains unclear, we report what we believe to be the first successful surgical treatment of serious respiratory dysfunction from pain generators in tissue that historically is considered anatomically and functionally separate from the mechanics of breathing. …”
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Intermittent hypoxia training improves cerebral blood flow without cognitive impairment by Qihan Zhang, Qing Wang, Feiyang Jin, Dan Huang, Xunming Ji, Yuan Wang

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Antimicrobial use regulations are associated with increased susceptibility among bovine Salmonella isolates from a U.S. surveillance system by Claudia Cobo-Angel, Maya Craig, Marwan Osman, Kevin J. Cummings, Casey L. Cazer

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Comparison of Effectiveness and Safety between Intraoperative 3D-CT-Guided and C-Arm-Guided Percutaneous Balloon Compression for Idiopathic Trigeminal Neuralgia:  A  Multi-Center R... by Xiong Xiao, Zhengjun Wei, Hao Ren, Hongtao Sun, Fang Luo

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Nurses’ Knowledge in the Prevention and Management of Nasointestinal Tube Obstruction: A Cross Sectional Study by Wang L, Hou W, Liu Z, Chen L, Lin R, Huang Y

“…Lun Wang,1,2 Wanling Hou,1 Zhong Liu,2 Li Chen,2 Ruidua Lin,2 Yinying Huang1 1Department of Nursing, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, Fujian Province, People’s Republic of China; 2Neurosurgery Department, Zhong Shan Hospital, Xiamen University, Xiamen, Fujian Province, People’s Republic of ChinaCorrespondence: Wanling Hou, Department of Nursing, Women and Children’s Hospital, School of Medicine, Xiamen University, 10 Zhen Hai Road, Si Ming District, Xiamen, Fujian Province, People’s Republic of China, Tel +8613705033186, Email hwldyx2007@126.comBackground: The nasointestinal tube is a route of nutritional support for patients and maintaining patency is essential. …”
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Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

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